Abstract: A multi-level hybrid algorithm filtering-type branch prediction method and prediction system includes: S1, arranging a first-stage branch target prediction table and a second-stage branch target prediction table; S2, any branch instruction accessing the first-stage branch target prediction table, determining whether the first-stage branch target prediction table hits, and if the first-stage branch target prediction table hits, then entering S3, and if the first-stage branch target prediction table does not hit, then entering S4; S3, determining whether a branch instruction of a current prediction is filtered out by the first-stage branch target prediction table, and if the branch instruction is filtered out, then entering S4, otherwise, then taking a prediction result provided by the first-stage branch target prediction table as a prediction address of the corresponding branch instruction; S4, accessing the second-stage branch target prediction table, and taking a prediction result provided by the second-stag

Abstract: Chimeric antigen receptors having a chlorotoxin domain and an IL-13 are described. These dual targeted chimeric antigen receptors are useful for treating glioblastoma and other cancers of neuroectodermal origin.

Abstract: Disclosed herein, inter alia, are methods of making and using engineered T cells useful for expressing a chimeric antigen receptor (CAR) targeted to a cell surface protein (e.g., a CAR targeted to IL13R?2, which is highly expressed on glioblastoma cells).

Abstract: This disclosure provides a method for preparing a current collector. The method includes: (1) anchoring vinyl groups onto the surface of textiles through the silanization between hydroxyl groups and coupling agents; (2) synthesizing polyelectrolyte brushes through in-situ radical polymerization; and (3) obtaining catalyst ions on the polyelectrolyte brushes through ion-exchange and obtaining metal-coated layers through subsequent electroless deposition). The current collector according to the present disclosure has high electrical conductivity and excellent mechanical flexibility, and thus the lithium ion battery including the same is suitable for portable and wearable electronic devices.

Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.

Abstract: A method for manufacturing T cell populations enriched for cells expressing CD27 and useful in T cell therapy is described. The T cell populations are also useful for a variety of purposes requiring a highly active, long-lived T cell population. Such cells elicit a superior antitumor immune response in vitro and in vivo.

Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.

Abstract: An electrode for a battery, comprising an active material and a metallic fabric is disclosed. The metallic fabric comprises fibers being at least partially covered by a coating of nickel or copper, which comprises a layer and a plurality of protrusions protruding from the layer. The active material is attached on the protrusions. The metallic fabric provides a high electrical conductivity and a high mechanical stability, and demonstrates outstanding performance for the use as a current collector of battery.

Abstract: This disclosure provides a method for preparing a current collector. The method includes: (1) anchoring vinyl groups onto the surface of textiles through the silanization between hydroxyl groups and coupling agents; (2) synthesizing polyelectrolyte brushes through in-situ radical polymerization; and (3) obtaining catalyst ions on the polyelectrolyte brushes through ion-exchange and obtaining metal-coated layers through subsequent electroless deposition). The current collector according to the present disclosure has high electrical conductivity and excellent mechanical flexibility, and thus the lithium ion battery including the same is suitable for portable and wearable electronic devices.

Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.

Abstract: An electrode for a battery, comprising an active material and a metallic fabric is disclosed. The metallic fabric comprises fibers being at least partially covered by a coating of nickel or copper, which comprises a layer and a plurality of protrusions protruding from the layer. The active material is attached on the protrusions. The metallic fabric provides a high electrical conductivity and a high mechanical stability, and demonstrates outstanding performance for the use as a current collector of battery.