Patents by Inventor Dongsheng Duan

Dongsheng Duan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adeno-associated viruses and uses thereof
    Publication number: 20080226600
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Application
    Filed: August 7, 2007
    Publication date: September 18, 2008
    Inventors: John F. Engelhardt, Dongsheng Duan, Ziying Yan
  • Compounds and methods to enhance rAAV transduction
    Publication number: 20080213221
    Abstract: Agents and methods to alter rAAV transduction are provided.
    Type: Application
    Filed: August 7, 2007
    Publication date: September 4, 2008
    Inventors: John F. Engelhardt, Dongsheng Duan
  • Adeno-associated viruses and uses thereof
    Publication number: 20080166758
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Application
    Filed: June 21, 2007
    Publication date: July 10, 2008
    Inventors: John F. Engelhardt, Dongsheng Duan, Ziying Yan
  • Adeno-associated virus vectors and uses thereof
    Patent number: 7241447
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: July 10, 2007
    Assignee: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan, Ziying Yan
  • Compounds and methods to enhance rAAV transduction
    Patent number: 7122335
    Abstract: Agents and methods to alter rAAV transduction, including agents and methods to enhance rAAV transduction, are provided. For instance, the invention provides methods to identify agents that enhance AAV transduction after viral binding to the cell membrane and before second strand synthesis.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: October 17, 2006
    Assignee: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan
  • Compounds and methods to enhance rAAV transduction
    Publication number: 20060093585
    Abstract: Agents and methods to alter rAAV transduction are provided.
    Type: Application
    Filed: December 13, 2005
    Publication date: May 4, 2006
    Inventors: John Engelhardt, Dongsheng Duan
  • Adeno-associated virus vectors
    Publication number: 20050255087
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Application
    Filed: February 15, 2005
    Publication date: November 17, 2005
    Inventors: John Engelhardt, Dongsheng Duan
  • Adeno-associated virus vectors
    Patent number: 6897045
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: May 24, 2005
    Assignee: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan
  • Adeno-associated virus vectors
    Publication number: 20020197237
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Application
    Filed: January 22, 2002
    Publication date: December 26, 2002
    Applicant: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan
  • Adeno-associated virus vectors
    Patent number: 6436392
    Abstract: The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: August 20, 2002
    Assignee: University of Iowa Research Foundation
    Inventors: John F. Engelhardt, Dongsheng Duan