Patents by Inventor Dongtak Jeong

Dongtak Jeong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR IMPROVING CARDIAC CONTRACTILITY
    Publication number: 20140243387
    Abstract: The present invention relates to regulation of cardiac contractile function. The present invention is based on the discovery that microRNAs contribute to the loss of cardiac contractility. Specifically, miR-25 binds to SERCA2a which results in a loss of function and interferes with Ca2+ handling. Accordingly, the present invention relates to methods of increasing cardiac contractile function by inhibiting miR-25. The invention further provides methods to identify agents that can modulate miR-25 activity, including high throughput screening methods, and provides a means to identify agents that are useful for treating patients having cardiac contractile function associated disorders.
    Type: Application
    Filed: December 17, 2013
    Publication date: August 28, 2014
    Applicants: Icahn School of Medicine at Mount Sinai, Sanford-Burnham Medical Research Institute
    Inventors: Mark Mercola, Agustin Rojas-Munoz, Christine Wahlquist, Alexandre Colas, Roger J. Hajjar, Dongtak Jeong