Patents by Inventor DONGXIAO SUN

DONGXIAO SUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods relating to aromatase inhibitor pharmacogenetics
    Patent number: 8476023
    Abstract: Methods for aiding in determining therapeutic efficacy of an aromatase inhibitor in a subject are provided according to embodiments of the present invention which include detecting expression and/or function of at least one UDP-glucuronosyltransferase having activity to modify at least one aromatase inhibitor and/or metabolite of the aromatase inhibitor by glucuronidation, wherein detection of expression and/or function of the UDP-glucuronosyltransferase is correlated with therapeutic efficacy of the aromatase inhibitor in the subject. Detection of UDP-glucuronosyltransferase expression and/or function includes detection of a UDP-glucuronosyltransferase gene deletion polymorphism in the subject.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: July 2, 2013
    Assignee: The Penn State Research Foundation
    Inventors: Philip Lazarus, Dongxiao Sun
  • METHODS RELATING TO AROMATASE INHIBITOR PHARMACOGENETICS
    Publication number: 20110033856
    Abstract: Methods for aiding in determining therapeutic efficacy of an aromatase inhibitor in a subject are provided according to embodiments of the present invention which include detecting expression and/or function of at least one UDP-glucuronosyltransferase having activity to modify at least one aromatase inhibitor and/or metabolite of the aromatase inhibitor by glucuronidation, wherein detection of expression and/or function of the UDP-glucuronosyltransferase is correlated with therapeutic efficacy of the aromatase inhibitor in the subject.
    Type: Application
    Filed: August 9, 2010
    Publication date: February 10, 2011
    Applicant: THE PENN STATE RESEARCH FOUNDATION
    Inventors: PHILIP LAZARUS, DONGXIAO SUN