Abstract: The present invention relates to a methods and composition in which a D-form or retro-inverso Pseudomonas pilin peptide, optionally having a polyethylene glycol moiety covalently attached to the peptide, is bound to a substrate. The disclosed methods and composition are useful for reducing the frictional coefficient, inhibiting biofilm formation by non-Pseudomonas bacteria, for reducing the inflammatory response to a material, for reducing corrosion of metals, and in biosensor applications.

Abstract: An approach for fingerprinting large data objects at the wire speed has been disclosed. The techniques include Fresh/Shift pipelining, split Fresh, optimization, online channel sampling, and pipelined selection. The architecture can also be replicated to work in parallel for higher system throughput. Fingerprinting may provide an efficient mechanism for identifying duplication in a data stream, and deduplication based on the identified fingerprints may provide reduced storage costs, reduced network bandwidth consumption, reduced processing time and other benefits. In some embodiments, fingerprinting may be used to ensure or verify data integrity and may facilitate detection of corruption or tampering. An efficient manner of generating fingerprints (either via hardware, software, or a combination) may reduce a computation load and/or time required to generate fingerprints.

Abstract: An approach for fingerprinting large data objects at the wire speed has been disclosed. The techniques include Fresh/Shift pipelining, split Fresh, optimization, online channel sampling, and pipelined selection. The architecture can also be replicated to work in parallel for higher system throughput. Fingerprinting may provide an efficient mechanism for identifying duplication in a data stream, and deduplication based on the identified fingerprints may provide reduced storage costs, reduced network bandwidth consumption, reduced processing time and other benefits. In some embodiments, fingerprinting may be used to ensure or verify data integrity and may facilitate detection of corruption or tampering. An efficient manner of generating fingerprints (either via hardware, software, or a combination) may reduce a computation load and/or time required to generate fingerprints.

Abstract: The present invention relates to a methods and composition in which a D-form or retro-inverso Pseudomonas pilin peptide is bound to a substrate. The disclosed methods and composition are useful for inhibiting biofilm formation by non-Pseudomonas bacteria, for reducing the inflammatory response to a material, for reducing corrosion of metals, and in biosensor applications.

Abstract: The present invention relates to a method for covalently attaching a compound to a stainless steel, tin, iron, or titanium substrate, by contacting exposed surface(s) of the substrate with a synthetic pilin peptide containing a disulfide loop derived from the C-terminal receptor binding protein of Type IV P. aeruginosa (T4P) pilin, to bind the pilin peptide to the exposed surface(s), and covalently attaching the compound to the pilin peptide. Also disclosed are a substrate formed by the method and a biosensor device that uses the uses. Also disclosed are methods for improving the corrosion resistance, adhesive force, hardness and electron work function of certain metals.

Abstract: The present invention relates to a methods and composition in which a D-form or retro-inverso Pseudomonas pilin peptide is bound to a substrate. The disclosed methods and composition are useful for inhibiting biofilm formation by non-Pseudomonas bacteria, for reducing the inflammatory response to a material, for reducing corrosion of metals, and in biosensor applications.

Abstract: The present invention relates to a method for covalently attaching a compound to a stainless steel, tin, iron, or titanium substrate, by contacting exposed surface(s) of the substrate with a synthetic pilin peptide containing a disulfide loop derived from the C-terminal receptor binding protein of Type IV P. aeruginosa (T4P) pilin, to bind the pilin peptide to the exposed surface(s), and covalently attaching the compound to the pilin peptide. Also disclosed are a substrate formed by the method and a biosensor device that uses the uses. Also disclosed are methods for improving the corrosion resistance, adhesive force, hardness and electron work function of certain metals.