Patents by Inventor Dongye Wang

Dongye Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bipartite inhibitors of bacterial RNA polymerase
    Patent number: 8372839
    Abstract: The invention provides a compound having a structural formula (I): X-?-Y, wherein X is an moiety that binds to the Rif pocket of a bacterial RNA polymerase, Y is a moiety that binds to the secondary channel of a bacterial RNA polymerase, and ? is a linker. The compound can act as an inhibitor of bacterial RNA polymerase. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.
    Type: Grant
    Filed: November 4, 2006
    Date of Patent: February 12, 2013
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Richard H. Ebright, Dongye Wang
  • Bipartite Inhibitors of Bacterial RNA Polymerase
    Publication number: 20090137467
    Abstract: The invention provides a compound having a structural formula (I): X-?-Y, wherein X is an moiety that binds to the Rif pocket of a bacterial RNA polymerase, Y is a moiety that binds to the secondary channel of a bacterial RNA polymerase, and ? is a linker. The compound can act as an inhibitor of bacterial RNA polymerase. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.
    Type: Application
    Filed: November 4, 2006
    Publication date: May 28, 2009
    Inventors: Richard H. Ebright, Dongye Wang