Patents by Inventor Donn Wishka

Donn Wishka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080234303
    Abstract: The present invention relates to a compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formula and R1, R2, R13, A, K, M, L1, L2, X, Y1, Y2, Q, salt thereof, wherein R1, R2, R13, A, K, L1, L2, W, X, Z1, Z2, Y1, Y2, Z1, Z2, M, Q, W, X, m, p and q are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: December 20, 2006
    Publication date: September 25, 2008
    Inventors: Samit Bhattacharya, Michael Luzzio, Donn Wishka, Gonghua Pan, Arthur Brosius, Joel Arcari, James Southers, Kendra Nelson, Jun Xiao
  • Publication number: 20060173063
    Abstract: The present invention relates to exo-(t-butyl 2R(+))-2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate (formula 1) a novel compound, and the process for the preparation thereof, and novel intermediates therein.
    Type: Application
    Filed: February 19, 2004
    Publication date: August 3, 2006
    Inventors: Thomas Fevig, Tizah Anjeh, Jon Lawson, Daniel Walker, Donn Wishka
  • Publication number: 20060116395
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is W is where the variables have the definitions discussed herein. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat a disease or condition in which ?7 is known to be involved.
    Type: Application
    Filed: January 11, 2006
    Publication date: June 1, 2006
    Inventors: David Piotrowski, Eric Jacobsen, Brad Acker, Daniel Walker, Donn Wishka, Vincent Groppi
  • Publication number: 20050234092
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Application
    Filed: May 26, 2005
    Publication date: October 20, 2005
    Inventors: Daniel Walker, David Piotrowski, Eric Jacobsen, Brad Acker, Donn Wishka, Steven Reitz, Vincent Groppi
  • Publication number: 20050222196
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Application
    Filed: May 26, 2005
    Publication date: October 6, 2005
    Inventors: Daniel Walker, David Piotrowski, Eric Jacobsen, Brad Acker, Donn Wishka, Steven Reitz
  • Publication number: 20050215584
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat conditions or diseases in which ?7 is known to be involved.
    Type: Application
    Filed: December 3, 2004
    Publication date: September 29, 2005
    Inventors: Bruce Rogers, David Piotrowski, Daniel Walker, Eric Jacobsen, Brad Acker, Donn Wishka, Vincent Groppi
  • Publication number: 20050165047
    Abstract: The invention provides fumarate salts of N-[1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, compositions, racemic mixtures, or pure enantiomers thereof, and preparation thereof. The fumarate salts are useful to treat diseases or conditions in which ?7 nAChR is known to be involved.
    Type: Application
    Filed: October 8, 2004
    Publication date: July 28, 2005
    Inventors: Jon Selbo, Donn Wishka, Bradley Hewitt, David Rappath, Ahmad Sheikh
  • Publication number: 20050107425
    Abstract: The present invention relates to compositions and methods to treat ADHD with an ?7 nAChR full agonist and psychostimulants and/or monoamine reuptake inhibitors.
    Type: Application
    Filed: October 12, 2004
    Publication date: May 19, 2005
    Inventors: Bruce Rogers, David Piotrowski, Vicent Groppi, Eric Jacobsen, Jason Myers, Daniel Walker, Donn Wishka