Patents by Inventor Donna Kaye Wilson

Donna Kaye Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stereoselective method for synthesizing dolaphenine
    Patent number: 6020495
    Abstract: The present invention relates to a method for the stereospecific synthesis of an enantiomer of a chiral amine, wherein the chiral amine has the formula R.sup.1 CH(NH.sub.2)R.sup.2. R.sup.1 and R.sup.2 are each independently selected from the group consisting of alkyl, aryl and heterocyclic and radicals. This method is particularly useful for stereospecifically synthesizing S-dolaphenine. The method involves contacting a chiral enantiomer of norephedrine with borane, within an aprotic solvent to form a complex for stereospecifically reducing oximes. The complex is then contacted with an oxime, thereby stereospecifically reducing said oxime to form an enantiomer of a chiral amine.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: February 1, 2000
    Assignee: Pharm-Eco Laboratories, Inc.
    Inventors: Xiaoyong Sun, Yesh P. Sachdeva, Donna Kaye Wilson, Richard L. Gabriel, Siya Ram
  • Stereoselective method for synthesizing dolaphenine
    Patent number: 5750713
    Abstract: The present invention relates to a method for the stereospecific synthesis of an enantiomer of a chiral amine, wherein the chiral amine has the formula R.sup.1 CH(NH.sub.2)R.sup.2. R.sup.1 and R.sup.2 are each independently selected from the group consisting of alkyl, aryl and heterocyclic and radicals. This method is particularly useful for stereospecifically synthesizing S-dolaphenine. The method involves contacting a chiral enantiomer of norephedrine with borane, within an aprotic solvent to form a complex for stereospecifically reducing oximes. The complex is then contacted with an oxime, thereby stereospecifically reducing said oxime to form an enantiomer of a chiral amine.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: May 12, 1998
    Assignee: Pharm-Eco Laboratories, Inc.
    Inventors: Xiaoyong Sun, Yesh P. Sachdeva, Donna Kaye Wilson, Richard L. Gabriel, Siya Ram