Patents by Inventor Donna M. Peehl

Donna M. Peehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER WITH ANDROGEN DEPRIVATION THERAPY IN COMBINATION WITH AN INHIBITOR OF THE SP1 TRANSCRIPTION FACTOR
    Publication number: 20210046106
    Abstract: Methods for treating cancer using combination therapy with an inhibitor of the Sp1 transcription factor and radiation therapy are disclosed.
    Type: Application
    Filed: May 26, 2020
    Publication date: February 18, 2021
    Inventors: Susan J. Knox, Donna M. Peehl, Junqiang Tian
  • Prostate cancer glycan markers and autoantibody signatures
    Patent number: 7981625
    Abstract: Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate cancers of various Gleason grades. The glyco-epitopes exist on the surfaces of prostate cells. The methods also comprise the detection of autoantibodies in prostate cancer subjects. The antibodies bound to a glyco-motif of N-glycans that is normally “cryptic.” This target is highly expressed in prostate cancers. Lectins and antibodies that detect these glyco-epitopes that expressed in prostate cancer tissues include Euonymus europaeus lectin (EEL); Psophocarpus Tetragonolobus Lectin-I (PTL-I); Griffonia Simplicifolia Lectin-I-A4 (GSL-I-A4); Griffonia Simplicifolia Lectin-I-B4 (GSL-I-B4); Sambucus nigra I agglutinin (SNA-I; Phaseolus vulgaris-L (PHA-L; Galanthus nivalis agglutinin (GNA); Narcissus pseudonarcissus agglutinin (NPA); Artocarpus integrifolia agglutinin (Jacalin); and mAb TM10 (IgM).
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: July 19, 2011
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Denong Wang, Leonore A. Herzenberg, Donna M. Peehl, Leonard A. Herzenberg
  • Prostate Cancer Glycan Markers and Autoantibody Signatures
    Publication number: 20090258792
    Abstract: Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate cancers of various Gleason grades. The glyco-epitopes exist on the surfaces of prostate cells. The methods also comprise the detection of autoantibodies in prostate cancer subjects. The antibodies bound to a glyco-motif of N-glycans that is normally “cryptic.” This target is highly expressed in prostate cancers. Lectins and antibodies that detect these glyco-epitopes that expressed in prostate cancer tissues include Euonymus europaeus lectin (EEL); Psophocarpus Tetragonolobus Lectin-I (PTL-I); Griffonia Simplicifolia Lectin-I-A4 (GSL-I-A4); Griffonia Simplicifolia Lectin-I-B4 (GSL-I-B4); Sambucus nigra I agglutinin (SNA-I; Phaseolus vulgaris-L (PHA-L; Galanthus nivalis agglutinin (GNA); Narcissus pseudonarcissus agglutinin (NPA); Artocarpus integrifolia agglutinin (Jacalin); and mAb TM10 (IgM).
    Type: Application
    Filed: April 10, 2009
    Publication date: October 15, 2009
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Denong Wang, Leonore A. Herzenberg, Donna M. Peehl, Leonard A. Herzenberg