Patents by Inventor Dontcho V. Jelev

Dontcho V. Jelev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYPICAN 2 AS A CANCER MARKER AND THERAPEUTIC TARGET
    Publication number: 20240084034
    Abstract: The present disclosure is directed to antibodies binding to Glypican 2 and methods of using such antibodies to treat cancers that express or overexpress the Glypican 2 antigen.
    Type: Application
    Filed: October 31, 2023
    Publication date: March 14, 2024
    Applicants: THE CHILDREN'S HOSPITAL OF PHILADELPHIA, THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY
    Inventors: John M. MARIS, Kristopher R. BOSSE, Dimiter DIMITROV, Zhongyu ZHU, Dontcho V. JELEV
  • Glypican 2 as a cancer marker and therapeutic target
    Patent number: 11814440
    Abstract: The present disclosure is directed to antibodies binding to Glypican 2 and methods of using such antibodies to treat cancers that express or overexpress the Glypican 2 antigen.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: November 14, 2023
    Assignees: The Children's Hospital of Philadelphia, The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: John M. Maris, Kristopher R. Bosse, Dimiter Dimitrov, Zhongyu Zhu, Dontcho V. Jelev
  • CHIMERIC ANTIGEN RECEPTORS CONTAINING GLYPICAN 2 BINDING DOMAINS
    Publication number: 20220257653
    Abstract: The present disclosure is directed to chimeric antigen receptors binding to Glypican 2, nucleic acids encoding the same, and cells expressing the same, and methods of using such cells to treat cancers that express or overexpress the Glypican 2 antigen.
    Type: Application
    Filed: July 17, 2020
    Publication date: August 18, 2022
    Applicants: The Children's Hospital of Philadelphia, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Kristopher BOSSE, John MARIS, David BARRETT, Jessica FOSTER, Dimiter DIMITROV, Crystal MACKALL, Robbie MAJZNER, ZHONGYU ZHU, Sabine HEITZENEDER, Dontcho V. JELEV
  • Molecules that bind to SARS-CoV-2
    Patent number: 10822379
    Abstract: This document provides methods and materials involved in binding a binder (e.g., an antibody, antigen binding fragment, and/or antibody domain) to a SARS-CoV-2 antigen. For example, binders (e.g., antibodies, antigen binding fragments, and antibody domains) that bind to a SARS-CoV-2 polypeptide and methods and materials for using one or more such binding molecules to treat a mammal (e.g., a human) having COVID-19 (or a viral infection caused by SARS-CoV-2) are provided.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: November 3, 2020
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Dimiter Stanchev Dimitrov, Chuan Chen, Dontcho V. Jelev, John W. Mellors, Wei Li, Zehua Sun
  • PHENOTYPE-NEUTRAL BARCODES FOR DIGITAL ANALYSIS
    Publication number: 20150225770
    Abstract: Processes of specifically and effectively labeling an organism are provided. Processes involve the incorporation of a plurality of phenotype neutral tags that are differentially detected where the presence or absence of the tag is represented by a digital readout. The incorporation of stealth tags or insertion tags provides a rapid and population maintaining labeling of an organism that can be readily identified by digital PCR techniques.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 13, 2015
    Applicant: U.S. Army Research Laboratory ATTN: RDRL-LOC-I
    Inventors: Dontcho V. Jelev, Henry S. Gibbons, Tsvetanka S. Zheleva