Patents by Inventor Dora Lis

Dora Lis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COPOLYMER 1 RELATED POLYPEPTIDES FOR USE AS MOLECULAR WEIGHT MARKERS AND FOR THERAPEUTIC USE
    Publication number: 20140194593
    Abstract: The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases. In addition, the subject invention provides pharmaceutical compositions for the treatment of immune diseases comprising a polypeptide having an identified molecular weight and an amino acid composition corresponding to glatiramer acetate or a terpolymer.
    Type: Application
    Filed: January 31, 2013
    Publication date: July 10, 2014
    Applicant: Yeda Research and Development Co., Ltd.
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Patent number: 8399211
    Abstract: The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolypmers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases. In addition, the subject invention provides pharmaceutical compositions for the treatment of immune diseases comprising a polypeptide having an identified molecular weight and an amino acid composition corresponding to glatiramer acetate or a terpolymer.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: March 19, 2013
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Publication number: 20100210817
    Abstract: The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases.
    Type: Application
    Filed: September 22, 2009
    Publication date: August 19, 2010
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Patent number: 7615359
    Abstract: The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases. In addition, the subject invention provides pharmaceutical compositions for the treatment of immune diseases comprising a polypeptide having an identified molecular weight and an amino acid composition corresponding to glatiramer acetate or a terpolymer.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: November 10, 2009
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Publication number: 20070048794
    Abstract: The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases. In addition, the subject invention provides pharmaceutical compositions for the treatment of immune diseases comprising a polypeptide having an identified molecular weight and an amino acid composition corresponding to glatiramer acetate or a terpolymer.
    Type: Application
    Filed: August 10, 2006
    Publication date: March 1, 2007
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Patent number: 7163802
    Abstract: The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolypmers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases. In addition, the subject invention provides pharmaceutical compositions for the treatment of immune diseases comprising a polypeptide having an identified molecular weight and an amino acid composition corresponding to glatiramer acetate or a terpolymer.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: January 16, 2007
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Patent number: 7074580
    Abstract: The present invention provides processes for determining the molecular weight of glatiramer acetate and other copolymers using molecular weight markers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: July 11, 2006
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Publication number: 20050256046
    Abstract: The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases.
    Type: Application
    Filed: March 25, 2005
    Publication date: November 17, 2005
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Publication number: 20050038233
    Abstract: The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate orcorresponding copolymers and can be used for treating or preventing various immune diseases.
    Type: Application
    Filed: March 2, 2004
    Publication date: February 17, 2005
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Patent number: 6800287
    Abstract: The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: October 5, 2004
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Patent number: 6514938
    Abstract: The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight. The molecular weight markers also optimally demonstrate biological activity similar to glatiramer acetate or corresponding copolymers and can be used for treating or preventing various immune diseases. In addition, the subject invention provides pharmaceutical compositions for the treatment of immune diseases comprising a polypeptide having an identified molecular weight and an amino acid composition corresponding to glatiramer acetate or a terpolymer.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: February 4, 2003
    Assignee: Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
    Inventors: Alexander Gad, Dora Lis
  • Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
    Publication number: 20020115103
    Abstract: The present invention provides molecular weight markers for accurate determination of the molecular weight of glatiramer acetate and other copolymers. The present invention further provides a plurality of molecular weight markers for determining the molecular weight of glatiramer acetate and other copolymers which display linear relationships between molar ellipticity and molecular weight, and between retention time and the log of the molecular weight.
    Type: Application
    Filed: March 23, 2001
    Publication date: August 22, 2002
    Inventors: Alexander Gad, Dora Lis