Patents by Inventor Dora M. Kovacs

Dora M. Kovacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for modulating transcription from the amyloid .beta.-protein precursor (APP) promoter
    Patent number: 5643726
    Abstract: The application concerns methods for modulating transcription from the amyloid .beta.-protein precursor (APP) promoter. The upstream stimulatory factor (USF) is described as being capable of activating transcription from the APP promoter. Also described are USF binding compounds which are capable of down-regulating expression from the APP promoter. Preferred USF binding compounds are the amyloid precursor-like proteins APLP1 and APLP2. The application further concerns a screening assay for determining which candidate USF binding compounds are capable of causing down-regulation of transcription from the APP promoter.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: July 1, 1997
    Assignee: The General Hospital Corporation
    Inventors: Rudolph E. Tanzi, Dora M. Kovacs