Patents by Inventor Doreen Krumbiegel

Doreen Krumbiegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteins that bind PI16 and uses thereof
    Patent number: 9605079
    Abstract: The present disclosure provides an isolated protein comprising at least one antibody variable region that is capable of binding to peptidase inhibitor 16 (PI16), wherein the protein is also capable of competitively inhibiting binding of an antibody produced by a hybridoma designated CRCBT-02-001 deposited with the ATCC under Accession Number PTA-10685 to PI16. The present invention also provides use of the protein, e.g., in diagnosis, therapy or to isolate cells, preferably Treg cells.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: March 28, 2017
    Assignee: MEDVET SCIENCE PTY LTD.
    Inventors: Simon Barry, Doreen Krumbiegel, Nicola Ga-Ling Eastaff-Leung, Ian Cameron Nicholson, Heddy Zola
  • BIOMARKERS AND USES THEREOF
    Publication number: 20160320388
    Abstract: The present invention provides markers of regulatory T (Treg) cells, preferably, cell surface markers of Treg cells and uses of those markers or compounds that bind thereto to identify or isolate Treg cells or to diagnose/prognose/treat/prevent Treg-mediated conditions. The present invention also provides methods for identification and/or isolation of Treg cell subpopulations and such isolated subpopulations of Treg cells.
    Type: Application
    Filed: June 13, 2016
    Publication date: November 3, 2016
    Inventors: Simon Barry, Timothy John Sadlon, Stephen Martin Pederson, Bridget Gabrielle Wilkinson, Doreen Krumbiegel, Ian Cameron Nicholson, Heddy Zola
  • PROTEINS THAT BIND PI16 AND USES THEREOF
    Publication number: 20130171153
    Abstract: The present disclosure provides an isolated protein comprising at least one antibody variable region that is capable of binding to peptidase inhibitor 16 (PI16), wherein the protein is also capable of competitively inhibiting binding of an antibody produced by a hybridoma designated CRCBT-02-001 deposited with the ATCC under Accession Number PTA-10685 to PI16. The present invention also provides use of the protein, e.g., in diagnosis, therapy or to isolate cells, preferably Treg cells.
    Type: Application
    Filed: April 18, 2011
    Publication date: July 4, 2013
    Applicant: TransBio Ltd.
    Inventors: Simon Barry, Doreen Krumbiegel, Nicola Ga-Ling Eastaff-Leung, Ian Cameron Nicholson, Heddy Zola
  • BIOMARKERS AND USES THEREOF
    Publication number: 20120064100
    Abstract: The present invention provides markers of regulatory T (Treg) cells, preferably, cell surface markers of Treg cells and uses of those markers or compounds that bind thereto to identify or isolate Treg cells or to diagnose/prognose/treat/prevent Treg-mediated conditions. The present invention also provides methods for identification and/or isolation of Treg cell subpopulations and such isolated subpopulations of Treg cells.
    Type: Application
    Filed: March 18, 2010
    Publication date: March 15, 2012
    Inventors: Simon Barry, Timothy John Sadlon, Stephen Martin Pederson, Bridget Gabrielle Wilkinson, Doreen Krumbiegel, Ian Cameron Nicholson, Heddy Zola