Patents by Inventor Dori Thomas-Karyat

Dori Thomas-Karyat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALK5 inhibitors and their uses
    Patent number: 11987558
    Abstract: The present disclosure relates to ALK5 inhibitors and their uses.
    Type: Grant
    Filed: March 24, 2023
    Date of Patent: May 21, 2024
    Assignee: Synthis Therapeutics, Inc.
    Inventor: Dori A. Thomas-Karyat
  • ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES
    Publication number: 20230132568
    Abstract: The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.
    Type: Application
    Filed: December 23, 2022
    Publication date: May 4, 2023
    Applicant: Synthis Therapeutics, Inc.
    Inventor: Dori A. Thomas-Karyat
  • ALK5 INHIBITOR CONJUGATES AND USES THEREOF
    Publication number: 20230090552
    Abstract: The present disclosure relates to targeted drug conjugates comprising ALK5 inhibitors and targeting moieties that direct the ALK5 inhibitors to cells involved in fibrosis and cancer, for example myofibroblasts, activated fibroblasts and transitioning fibroblasts, and their uses, in particular wherein the ALK5 inhibitor is N-methyl-2-(4-(4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)phenoxy)ethan-1-amine.
    Type: Application
    Filed: January 7, 2021
    Publication date: March 23, 2023
    Applicant: Synthis Therapeutics, Inc.
    Inventor: Dori Thomas-Karyat
  • Antibody-ALK5 inhibitor conjugates and their uses
    Patent number: 11583593
    Abstract: The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: February 21, 2023
    Assignee: Synthis Therapeutics, Inc.
    Inventor: Dori A. Thomas-Karyat
  • ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES
    Publication number: 20220249680
    Abstract: The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.
    Type: Application
    Filed: July 9, 2019
    Publication date: August 11, 2022
    Applicant: Synthis Therapeutics, Inc.
    Inventor: Dori Thomas-Karyat
  • ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES
    Publication number: 20210299268
    Abstract: The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.
    Type: Application
    Filed: July 9, 2018
    Publication date: September 30, 2021
    Applicant: Synthis Therapeutics, Inc.
    Inventor: Dori Thomas-Karyat
  • ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES
    Publication number: 20200147234
    Abstract: The present disclosure relates to antibody-drug conjugates comprising ALK5 inhibitors and their uses.
    Type: Application
    Filed: October 16, 2019
    Publication date: May 14, 2020
    Applicant: Synthis, LLC
    Inventor: Dori A. Thomas-Karyat