Patents by Inventor Dorin Panescu

Dorin Panescu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11583204
    Abstract: A minimally invasive system comprises an elongate medical instrument including a flexible body. The flexible body includes a wall including a channel, and the channel includes a groove. The flexible body further includes a lumen defined by an interior surface of the wall and a curved distal tip portion. The elongate medical instrument further includes a shape sensor coupled to the flexible body. The shape sensor is at least partially positioned within the groove, and the shape sensor is configured to detect shape characteristics of at least a portion of the flexible body. The system further includes an actuator for manipulating the elongate medical instrument.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: February 21, 2023
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Vincent Duindam, Simon P. DiMaio, David Q. Larkin, Dorin Panescu, Giuseppe Maria Prisco
  • Patent number: 11576714
    Abstract: According to some embodiments, a medical instrument comprises an elongate body having a proximal end and a distal end and a pair of electrodes or electrode portions (for example, a split-tip electrode assembly). Systems and methods are described herein that perform contact sensing and/or ablation confirmation based on electrical measurements obtained while energy of different frequencies are applied to the pair of electrodes or electrode portions. The contact sensing systems and methods may calibrate network parameter measurements to compensate for a hardware unit in a network parameter measurement circuit or to account for differences in cables, instrumentation or hardware used.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: February 14, 2023
    Assignee: Epix Therapeutics, Inc.
    Inventors: Dorin Panescu, Jessi E Johnson
  • Patent number: 11534227
    Abstract: According to some embodiments, a method of confirming successful ablation of targeted cardiac tissue of a subject using a high-resolution mapping electrode comprises pacing said cardiac tissue at a predetermined pacing level to increase the heart rate of the subject from a baseline level to an elevated level, the predetermined pacing level being greater than a pre-ablation pacing threshold level but lower than a post-ablation pacing threshold level, delivering ablative energy to the ablation electrode, detecting the heart rate of the subject, wherein the heart rate detected by the high-resolution mapping electrode is at the elevated level before the post-ablation pacing threshold level is achieved, and wherein the heart rate detected by the high-resolution mapping electrode drops below the elevated level once ablation achieves its therapeutic goal or target, and terminating the delivery of ablative energy to the ablation electrode after the heart rate drops below the elevated level.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: December 27, 2022
    Assignee: EPiX Therapeutics, Inc.
    Inventor: Dorin Panescu
  • Publication number: 20220346751
    Abstract: A method of planning a procedure to deploy an interventional instrument comprises receiving a model of an anatomic structure. The anatomic structure includes a plurality of passageways. The method further includes identifying a target structure in the model and receiving information about an operational capability of the interventional instrument within the plurality of passageways. The method further comprises identifying a planned deployment location for positioning a distal tip of the interventional instrument to perform the procedure on the target structure based upon the operational capability of the interventional instrument.
    Type: Application
    Filed: July 18, 2022
    Publication date: November 3, 2022
    Inventors: Caitlin Q. Donhowe, Prashant Chopra, Dorin Panescu, Carol Reiley, Tao Zhao
  • Publication number: 20220323146
    Abstract: Radiometric systems may comprise a radiometer, an antenna and a processor communicatively coupled together. The processor may provide a contact-focused output based on filtering or other processing of a raw radiometric output signal. The contact-focused output may facilitate determination of whether contact has been achieved and/or assessment of contact. A miniaturized reflectometer may be configured to determine an amount of reflected power from the antenna. The processor may be configured to determine a reflection coefficient of the reflected power determined by the reflectometer and to identify tissue type based on the reflection coefficient. Systems and methods for facilitating deeper temperature measurements of a radiometer are described.
    Type: Application
    Filed: June 13, 2022
    Publication date: October 13, 2022
    Inventors: Dorin Panescu, Jessi E. Johnson, Josef Vincent Koblish, John F. McCarthy
  • Patent number: 11426141
    Abstract: A system for performing an interventional procedure comprises an interventional instrument and a control system.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: August 30, 2022
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Caitlin Q. Donhowe, Prashant Chopra, Dorin Panescu, Carol Reiley, Tao Zhao
  • Patent number: 11419538
    Abstract: Methods and apparatuses, including devices and systems, for remote and detection and/or diagnosis of acute myocardial infarction (AMI). In particular, described herein are handheld and adhesive devices having an electrode configuration capable of recording three orthogonal ECG lead signals in an orientation-specific manner, and transmitting these signals to a processor. The processor may be remote or local, and it may automatically or semi-automatically detect AMI, atrial fibrillation or other heart disorders based on the analyses of the deviation of the recorded 3 cardiac signals with respect to previously stored baseline recordings.
    Type: Grant
    Filed: January 6, 2022
    Date of Patent: August 23, 2022
    Assignee: HeartBeam, Inc.
    Inventors: Branislav Vajdic, Dorin Panescu, Bosko Bojovic, Ljupco Hadzievski, Vladan Vukcevic, Uros Mitrovic, Marjan Miletic
  • Publication number: 20220257315
    Abstract: Apparatuses and methods for treating a heart failure patient by ablating a nerve of the thoracic splanchnic sympathetic nervous system to increase venous capacitance and reduce pulmonary blood pressure. A method comprising: inserting a catheter into a vein adjacent the nerve, applying stimulation energy and observing hemodynamic effects, applying ablation energy and observing hemodynamic effects, applying simulation energy after the ablation and observing hemodynamic effects and monitoring for presence of the lung in the ablation zone. An alternative method comprising: inserting a catheter into a vein adjacent the nerve, detecting that lung tissue is a safe distance from an ablation zone, and delivering ablation energy to the target nerve when lung tissue is a safe distance from the ablation zone.
    Type: Application
    Filed: October 26, 2021
    Publication date: August 18, 2022
    Inventors: Howard LEVIN, Mark GELFAND, Zoar Jacob ENGELMAN, Dorin PANESCU, Mark S. LEUNG
  • Publication number: 20220241013
    Abstract: A system is provided that includes a Q3D endoscope disposed to image a field of view and a processor that produces a Q3D model of a scene and identifies target instruments and structures. The processor is configured to display the scene from a virtual field of view of an instrument, to determine a no fly zone around targets, to determine a predicted path for said instruments or to provide 3D tracking of said instruments.
    Type: Application
    Filed: February 14, 2022
    Publication date: August 4, 2022
    Inventors: Dorin Panescu, Daniel H. Jones, Christopher B. Allenby
  • Publication number: 20220233235
    Abstract: A system for treatment of patient tissue by delivery of high-voltage pulses comprising an ablation catheter, a measurement unit and an electronic control unit (ECU). The measurement unit is configured to perform measurements using an energy source, whereby the impedance and/or current measurement values are determined as response to an alternating voltage and/or at least one voltage pulse. The ECU is configured to receive and analyze said measurement values provided by the measurement unit and determine arcing risk (AR) indexes for said electrode pairs and/or a contact uniformity (CU) value based on said impedance measurement values and/or impedances for said electrodes and/or an impedance uniformity (IU) value based on said current measurement values.
    Type: Application
    Filed: December 28, 2021
    Publication date: July 28, 2022
    Applicant: CRC EP, Inc.
    Inventors: Henning Ebert, Steffen Holzinger, Dorin Panescu
  • Publication number: 20220233236
    Abstract: The invention relates to an ablation catheter for treatment of a patient's tissue by delivery of high-voltage pulses comprising a catheter shaft and an ablation portion being arranged at a distal end of the catheter shaft with a plurality of electrodes accommodated along the ablation portion, wherein the ablation portion forms a spiral and comprises a first loop section and a neighboring second loop section, wherein an inner diameter of the first loop section increases towards an inner diameter of the second loop section starting from a first end of the first loop section located opposite the second loop section, wherein the first loop section has a greater stiffness than the second loop section.
    Type: Application
    Filed: January 20, 2022
    Publication date: July 28, 2022
    Applicant: CRC EP, Inc.
    Inventors: Cary Hata, Alan de la Rama, Dorin Panescu
  • Publication number: 20220233234
    Abstract: The invention relates to an ablation catheter for treatment of a patient's tissue, for example for a PVI procedure on a patient's heart, comprising an elongated catheter shaft and an ablation portion being arranged at a distal end of the catheter shaft with a plurality of electrodes accommodated along the ablation portion, wherein the ablation portion comprises at least two loop sections forming a three-dimensional spiral. In order to increase safety of ablation treatment, spare adjacent tissue (e.g. nerves, vessels, esophagus) and shorten ablation time, a pitch, or clearance of two neighboring loop sections is greater than an ionization threshold of the medium around the distal section, for example blood or gases resulted from electrolysis. The invention further relates to an operation method of such ablation catheter.
    Type: Application
    Filed: December 28, 2021
    Publication date: July 28, 2022
    Applicant: CRC EP, Inc.
    Inventors: Dorin Panescu, Cary Hata, Alan de la Rama, Henning Ebert, Steffen Holzinger
  • Patent number: 11389230
    Abstract: Systems, devices and methods of determining orientation of a distal end of a medical instrument (e.g., electrode-tissue orientation of an RF ablation catheter) are described herein. One or more processors may be configured to receive temperature measurements from each of a plurality of temperature-measurement devices distributed along a length of the distal end of the medical instrument and determine the orientation from a group of two or more possible orientation options based on whether temperature measurement values or characteristics of temperature response determined from the temperature measurement values satisfy one or more orientation criteria.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: July 19, 2022
    Assignee: Epix Therapeutics, Inc.
    Inventors: Dorin Panescu, Josef Vincent Koblish, Donghoon Chun, Jessi E. Johnson, Eric Andrew Schultheis
  • Patent number: 11357568
    Abstract: Radiometric systems may comprise a radiometer, an antenna and a processor communicatively coupled together. The processor may provide a contact-focused output based on filtering or other processing of a raw radiometric output signal. The contact-focused output may facilitate determination of whether contact has been achieved and/or assessment of contact. A miniaturized reflectometer may be configured to determine an amount of reflected power from the antenna. The processor may be configured to determine a reflection coefficient of the reflected power determined by the reflectometer and to identify tissue type based on the reflection coefficient. Systems and methods for facilitating deeper temperature measurements of a radiometer are described.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: June 14, 2022
    Assignee: Epix Therapeutics, Inc.
    Inventors: Dorin Panescu, Jessi E. Johnson, Josef Vincent Koblish, John F. McCarthy
  • Publication number: 20220125363
    Abstract: Methods and apparatuses, including devices and systems, for remote and detection and/or diagnosis of acute myocardial infarction (AMI). In particular, described herein are handheld and adhesive devices having an electrode configuration capable of recording three orthogonal ECG lead signals in an orientation-specific manner, and transmitting these signals to a processor. The processor may be remote or local, and it may automatically or semi-automatically detect AMI, atrial fibrillation or other heart disorders based on the analyses of the deviation of the recorded 3 cardiac signals with respect to previously stored baseline recordings.
    Type: Application
    Filed: January 6, 2022
    Publication date: April 28, 2022
    Inventors: Branislav VAJDIC, Dorin PANESCU, Bosko BOJOVIC, Ljupco HADZIEVSKI, Vladan VUKCEVIC, Uros MITROVIC, Marjan MILETIC
  • Patent number: 11304771
    Abstract: A system is provided to provide haptic feedback during a medical procedure comprising: a quantitative three-dimensional (Q3D); a surgical instrument disposed to deform a tissue structure; a haptic user interface device configured to provide an indication of tissue structure deformation in response to information indicative of the measure of tissue structure deformation; and a processor configured to produce a Q3D model that includes information indicative of a measure of tissue structure deformation and to provide the information indicative of the measure of tissue structure deformation to the haptic user interface device.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: April 19, 2022
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Dorin Panescu, Daniel H. Jones, Christopher B. Allenby
  • Publication number: 20220079669
    Abstract: Systems, devices and methods of determining orientation of a distal end of a medical instrument (e.g., electrode-tissue orientation of an RF ablation catheter) are described herein. One or more processors may be configured to receive temperature measurements from each of a plurality of temperature-measurement devices distributed along a length of the distal end of the medical instrument and determine the orientation from a group of two or more possible orientation options based on whether temperature measurement values or characteristics of temperature response determined from the temperature measurement values satisfy one or more orientation criteria.
    Type: Application
    Filed: November 22, 2021
    Publication date: March 17, 2022
    Inventors: Dorin Panescu, Josef Vincent Koblish, Donghoon Chun, Jessi E. Johnson, Eric Andrew Schultheis
  • Patent number: 11266465
    Abstract: A system is provided that includes a Q3D endoscope disposed to image a field of view and a processor that produces a Q3D model of a scene and identifies target instruments and structures. The processor is configured to display the scene from a virtual field of view of an instrument, to determine a no fly zone around targets, to determine a predicted path for said instruments or to provide 3D tracking of said instruments.
    Type: Grant
    Filed: March 28, 2015
    Date of Patent: March 8, 2022
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Dorin Panescu, Daniel H Jones, Christopher Allenby
  • Publication number: 20220015680
    Abstract: Methods and apparatuses, including devices and systems, for remote and detection and/or diagnosis of acute myocardial infarction (AMI). In particular, described herein are handheld and adhesive devices having an electrode configuration capable of recording three orthogonal ECG lead signals in an orientation-specific manner, and transmitting these signals to a processor. The processor may be remote or local, and it may automatically or semi-automatically detect AMI, atrial fibrillation or other heart disorders based on the analyses of the deviation of the recorded 3 cardiac signals with respect to previously stored baseline recordings.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 20, 2022
    Inventors: Branislav VAJDIC, Dorin PANESCU, Bosko BOJOVIC, Ljupco HADZIEVSKI, Vladan VUKCEVIC, Uros MITROVIC, Marjan MILETIC
  • Patent number: 11179197
    Abstract: Systems, devices and methods of determining orientation of a distal end of a medical instrument (e.g., electrode-tissue orientation of an RF ablation catheter) are described herein. One or more processors may be configured to receive temperature measurements from each of a plurality of temperature-measurement devices distributed along a length of the distal end of the medical instrument and determine the orientation from a group of two or more possible orientation options based on whether temperature measurement values or characteristics of temperature response determined from the temperature measurement values satisfy one or more orientation criteria.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: November 23, 2021
    Assignee: Epix Therapeutics, Inc.
    Inventors: Dorin Panescu, Josef Vincent Koblish, Donghoon Chun, Jessi E. Johnson, Eric Andrew Schultheis