Abstract: Provided are dermal barrier compositions that create a barrier between external irritants or coverings and the skin of a subject upon which the composition is applied. A dermal barrier composition as provided herein includes hydrophilic polymer or copolymer and a fatty acid-amino acid conjugate. Also provided are methods of producing a dermal barrier composition. Also provided are methods of using a dermal barrier composition to maintain makeup on the skin of a subject.

Abstract: The present invention relates to methods and compositions for treating various side effects associated with the administration of one or more therapeutic compounds. In particular embodiments, the present invention relates to methods of reducing one or more adverse side effects associated with one or more therapeutic compounds by administering a neurotoxin, such as botulinum toxin, in combination with the one or more therapeutic compounds.