Patents by Inventor Doris Dea

Doris Dea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-Hydroxymethylglutaryl coenzyme a reductase and diagnosis and prognostication of dementia
    Publication number: 20050069881
    Abstract: The invention relates to methods and commercial packages for the diagnosis and/or prognostication of a dementia. The methods are based upon the assessment of a feature or features relating to 3-hydroxymethylglutaryl coenzyme A reductase (HMGR) gene, a polymorphism associated with the gene, the nature of mRNA transcripts produced, and/or HMGR protein activity. Applicants have determined that a decrease in HMGR activity correlates with Alzheimer disease. Applicants have further determined that the presence of a polymorphism in the HMGR gene correlates with Alzheimer disease. Applicants have identified two abnormal HMGR mRNA transcripts and have shown that their presence correlates with Alzheimer disease.
    Type: Application
    Filed: August 29, 2002
    Publication date: March 31, 2005
    Inventors: Judes Poirier, Louise Theroux-Lamarre, Doris Dea, Nicole Aumont