Patents by Inventor Doris M. Benbrook

Doris M. Benbrook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF ENDOPLASMIC RETICULUM STRESS-RELATED DISEASES AND CONDITIONS
    Publication number: 20130184323
    Abstract: A method of treating a disease or condition associated with at least one of a cellular accumulation of unfolded and/or misfolded proteins, an abnormal unfolded protein response (UPR), an endoplasmic reticulum (ER) stress, and an abnormal autophagy response, is disclosed.
    Type: Application
    Filed: February 27, 2013
    Publication date: July 18, 2013
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA
    Inventors: Doris M. Benbrook, Franklin A. Hays
  • TREATMENT AND INHIBITION OF DISEASE CONDITIONS USING FLEXIBLE HETEROAROTINOIDS
    Publication number: 20100105757
    Abstract: The present invention contemplates methods of treating, reducing, inhibiting or preventing several diseases by the administration of flexible heteroarotinoids. Among the diseases or conditions which can benefit from treatment with flexible heteroarotinoids as described herein are, (1) cancers and other diseases that involve abnormal differentiation, (2) diabetes, (3) hemophelia, (4) liver disease, (5) diseases involving human aldehyde dehydrogenase 2, (6) polycystic kidney disease, (7) lysosomal storage diseases, (8) high cholesterol, (9) obesity, (10) high triglycerides, (11) glycoprotein metabolism diseases, and (12) diseases involving abnormal angiogenesis.
    Type: Application
    Filed: October 29, 2009
    Publication date: April 29, 2010
    Inventors: Doris M. Benbrook, Martin Turman, Suresh Guruswamy
  • Treatment and inhibition of disease conditions using flexible heteroarotinoids
    Patent number: 7612107
    Abstract: The present invention contemplates methods of treating, reducing, inhibiting or preventing several diseases by the administration of flexible heteroarotinoids. Among the diseases or conditions which can benefit from treatment with flexible heteroarotinoids as described herein are, (1) cancers and other diseases that involve abnormal differentiation, (2) diabetes, (3) hemophilia, (4) liver disease, (5) diseases involving human aldehyde dehydrogenase 2, (6) polycystic kidney disease, (7) lysosomal storage diseases, (8) high cholesterol, (9) obesity, (10) high triglycerides, (11) glycoprotein metabolism diseases, and (12) diseases involving abnormal angiogenesis.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: November 3, 2009
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Doris M. Benbrook, Martin Turman, Suresh Guruswamy
  • Heteroarotinoids containing urea or thiourea linker
    Patent number: 6586460
    Abstract: Compounds, known as heteroarotinoids, having varying abilities to inhibit growth of certain cancerous cells, induce normal cell differentiation, and induce apoptosis or death of cancerous cells, of the general formula: in which: Ar and Ar′ denote aryl substituents, and wherein at least one of said aryl substituents comprises an aromatic ring having at least one heteroatom in a fused, partially saturated ring; W denotes O or S; and Q denotes H or i-C3H7.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: July 1, 2003
    Assignees: The Board of Regents for Oklahoma State University, The Board of Regents for University of Oklahoma
    Inventors: Kenneth Darrell Berlin, Doris M. Benbrook, Eldon C. Nelson