Abstract: A device for uniform ablation of the endometrium comprises a transparent inflatable coolable balloon, flexible cryoprobes operable to be advanced into the uterine cornuae, an applicator operable to deliver balloon and cryoprobes to and from the uterine cavity, and optional channels for a hysteroscope and a light source, enabling observation of the uterine cavity during device insertion and observation of the endometrium during various stages of the ablation process.

Abstract: An apparatus and method for protecting the neurovascular bundle during cryoablation of tissues of the prostate by heating the vicinity of the neurovascular bundle while cooling pathological tissues of a prostate to cryoablation temperatures, thereby cryoablating pathological tissues while protecting the neurovascular bundle from damage. A cryoprobe operable to cool a distal operating tip while heating a proximal shaft is presented.

Abstract: An apparatus and method for protecting the neurovascular bundle during cryoablation of tissues of the prostate by heating the vicinity of the neurovascular bundle while cooling pathological tissues of a prostate to cryoablation temperatures, thereby cryoablating pathological tissues while protecting the neurovascular bundle from damage. A cryoprobe operable to cool a distal operating tip while heating a proximal shaft is presented.

Abstract: The present invention relates to apparatus, systems, and methods utilizing cryogenic cooling in an angioplasty balloon catheter for treatment of arterial stenosis and prevention of restenosis. More particularly, the present invention relates to an angioplasty balloon catheter utilizing expansion of compressed gas to effect Joule-Thomson cooling of an angioplasty balloon, and optionally further incorporating external temperature sensors utilizable to identify a locus for treatment of arterial stenosis. The present invention further relates to angioplasty treatment systems incorporating such a catheter, and to cryogenic angioplasty methods for treating arterial stenosis and discouraging restenosis.

Abstract: The present invention relates to use of an introducer for delivering multiple thermal ablation probes to an organic target in a compact configuration, which probes are operable to be deployed in a dispersed configuration characterized by known and accurately maintained distances of one treatment head from another, which distances are substantially maintained during insertion of treatment heads into target tissues. In preferred embodiments, distal portions of deployed probe treatment heads are substantially parallel one to another.

Abstract: A device for uniform ablation of the endometrium comprises a transparent inflatable coolable balloon, flexible cryoprobes operable to be advanced into the uterine cornuae, an applicator operable to deliver balloon and cryoprobes to and from the uterine cavity, and optional channels for a hysteroscope and a light source, enabling observation of the uterine cavity during device insertion and observation of the endometrium during various stages of the ablation process.

Abstract: The present invention relates to apparatus, systems, and methods utilizing cryogenic cooling in an angioplasty balloon catheter for treatment of arterial stenosis and prevention of restenosis. More particularly, the present invention relates to an angioplasty balloon catheter utilizing expansion of compressed gas to effect Joule-Thomson cooling of an angioplasty balloon, and optionally further incorporating external temperature sensors utilizable to identify a locus for treatment of arterial stenosis. The present invention further relates to angioplasty treatment systems incorporating such a catheter, and to cryogenic angioplasty methods for treating arterial stenosis and discouraging restenosis.

Abstract: The present invention relates to apparatus, systems, and methods utilizing cryogenic cooling in an angioplasty balloon catheter for treatment of arterial stenosis and prevention of restenosis. More particularly, the present invention relates to an angioplasty balloon catheter utilizing expansion of compressed gas to effect Joule-Thomson cooling of an angioplasty balloon, and optionally further incorporating external temperature sensors utilizable to identify a locus for treatment of arterial stenosis. The present invention further relates to angioplasty treatment systems incorporating such a catheter, and to cryogenic angioplasty methods for treating arterial stenosis and discouraging restenosis.

Abstract: The present invention relates to apparatus, systems, and methods utilizing cryogenic cooling in an angioplasty balloon catheter for treatment of arterial stenosis and prevention of restenosis. More particularly, the present invention relates to an angioplasty balloon catheter utilizing expansion of compressed gas to effect Joule-Thomson cooling of an angioplasty balloon, and optionally further incorporating external temperature sensors utilizable to identify a locus for treatment of arterial stenosis. The present invention further relates to angioplasty treatment systems incorporating such a catheter, and to cryogenic angioplasty methods for treating arterial stenosis and discouraging restenosis.

Abstract: The present invention relates to apparatus, systems, and methods utilizing cryogenic cooling in an angioplasty balloon catheter for treatment of arterial stenosis and prevention of restenosis. More particularly, the present invention relates to an angioplasty balloon catheter utilizing expansion of compressed gas to effect Joule-Thomson cooling of an angioplasty balloon, and optionally further incorporating external temperature sensors utilizable to identify a locus for treatment of arterial stenosis. The present invention further relates to angioplasty treatment systems incorporating such a catheter, and to cryogenic angioplasty methods for treating arterial stenosis and discouraging restenosis.

Abstract: An apparatus and method for protecting the neurovascular bundle during cryoablation of tissues of the prostate by heating the vicinity of the neurovascular bundle while cooling pathological tissues of a prostate to cryoablation temperatures, thereby cryoablating pathological tissues while protecting the neurovascular bundle from damage. A cryoprobe operable to cool a distal operating tip while heating a proximal shaft is presented.

Abstract: The present invention relates to system, device, and method utilizing cryosurgery to treat a tumor of the breast. More particularly, the present invention relates to treating a breast tumor by inserting into a breast, at a selected site known to be a locus of a tumor, an introducer having at least one access port, operating a biopsy needle through an access port to perform a biopsy of tissues at the selected site, and operating a cryoprobe through an access port to cool body tissues to cryoablation temperatures, thereby ablating or downsizing the tumor. The present invention further relates to use of cryoablation to downsize a large malignant tumor as pre-operative preparation for conventional excision surgery.

Abstract: The present invention relates to apparatus, systems, and methods utilizing cryogenic cooling in an angioplasty balloon catheter for treatment of arterial stenosis and prevention of restenosis. More particularly, the present invention relates to an angioplasty balloon catheter utilizing expansion of compressed gas to effect Joule-Thomson cooling of an angioplasty balloon, and optionally further incorporating external temperature sensors utilizable to identify a locus for treatment of arterial stenosis. The present invention further relates to angioplasty treatment systems incorporating such a catheter, and to cryogenic angioplasty methods for treating arterial stenosis and discouraging restenosis.