Abstract: The disclosure relates, in certain aspects, to compounds that can be used to inhibit ?-lactamases, such as but not limited to OXA enzymes, such as but not limited to OXA-24, OXA-48, and/or OXA-58. In certain embodiments, these compounds can be used to inhibit activity of ?-lactamases in vitro and in vivo.

Abstract: Described herein are methods of recellularizing an organ or tissue matrix.

Abstract: Described herein are methods of recellularizing an organ or tissue matrix.

Abstract: The disclosure relates, in certain aspects, to compounds that can be used to inhibit ?-lactamases, such as but not limited to OXA enzymes, such as but not limited to OXA-24, OXA-48, and/or OXA-58. In certain embodiments, these compounds can be used to inhibit activity of ?-lactamases in vitro and in vivo.

Abstract: Described herein are methods of recellularizing an organ or tissue matrix.

Abstract: The invention provides for methods and materials to decellularize an organ or portion thereof and to recellularize such a decellularized organ or portion thereof to thereby generate an organ or portion thereof.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: Described herein are methods of recellularizing an organ or tissue matrix.

Abstract: Described herein are methods of recellularizing an organ or tissue matrix.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: Described herein are methods of recellularizing an organ or tissue matrix.

Abstract: The invention provides for methods and materials to decellularize an organ or portion thereof and to recellularize such a decellularized organ or portion thereof to thereby generate an organ or portion thereof.

Abstract: The invention provides for methods and materials to decellularize a solid organ and to recellularize such a decellularized organ to thereby generate a solid organ.

Abstract: The invention provides for adult cardiac uncommitted progenitor cells (UPCs), methods of making such cells, and methods of using such cells in the treatment, repair and/or regeneration of damaged cardiac tissue.

Abstract: Devices and methods whereby therapeutic agents may be injected into distinct organ locations in a minimally invasive manner. Most preferably the devices and methods employ a video-assisted thorascopic system (VATS) to enable a physician in real time to visually identify a distinct organ location into which therapeutic agent is to be injected. In particularly preferred forms, devices are provided for injecting a therapeutic agent into a tissue site which include a proximal handle, and a tubular barrel distally extending from the handle. The barrel has an injection needle at a distal end thereof which is most preferably angled relative to the barrel's elongate axis. The internal space of the barrel is sized and configured to receive a cartridge containing a therapeutic agent to be injected into the tissue site.