Patents by Inventor Dorminik Escher

Dorminik Escher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoglobulin frameworks which demonstrate enhanced statbility in the intracellular envioronment and methods of identifying same
    Publication number: 20060035320
    Abstract: Compositions are provided, which can be used as frameworks for the creation of very stable and soluble single-chain Fv antibody fragments. These frameworks have been selected for intracellular performance and are thus ideally suited for the creation of scFv antibody fragments or scFv antibody libraries for applications where stability and solubility are limiting factors for the performance of antibody fragments, such as in the reducing environment of a cell. Such frameworks can also be used to identify highly conserved residues and consensus sequences which demonstrate enhanced solubility and stability.
    Type: Application
    Filed: May 21, 2004
    Publication date: February 16, 2006
    Inventors: Kathrin Tissot, Stefan Ewert, Adrian Maur, Alcide Barberis, Dorminik Escher