Patents by Inventor Doron Markovits

Doron Markovits has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnosis and treatment of insulin dependent diabetes mellitus using heat shock protein determinents
    Patent number: 5780034
    Abstract: A 65 KD heat shock protein, proteins cross-reactive therewith, antibodies thereto or T cells specific thereto can be used for detecting in humans the existence of, a tendency to develop, or the initiation of a process leading to insulin dependent diabetes mellitus. Antibodies to hsp65 can be used to detect the hsp65 molecule in blood or urine. The hsp65 molecule of any species, or any other substance immunologically cross-reactive therewith, when administered with a tolerogenic carrier, can be used for the prevention or treatment of IDDM prior to development of clinical symptoms thereof. T cells, active fragments thereof or the receptor peptide thereof can also be used for prevention or treatment of IDDM.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: July 14, 1998
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irun R. Cohen, Dana Elias, Doron Markovits
  • Kit for the diagnosis of insulin dependent diabetes mellitus
    Patent number: 5671848
    Abstract: A 65 KD heat shock protein, proteins cross-reactive therewith, or antibodies thereto can be used for detecting in humans the existence of, a tendency to develop, or the initiation of a process leading to insulin dependent diabetes mellitus. Antibodies to hsp65 can be used to detect the hsp65 molecule in blood or urine. The hsp65 molecule of any species, or any other substance immunologically cross-reactive therewith, when administered with a tolerogenic carrier, can be used for the prevention or treatment of IDDM prior to development of clinical symptoms thereof.
    Type: Grant
    Filed: March 29, 1993
    Date of Patent: September 30, 1997
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irun Robert Cohen, Dana Elias, Doron Markovits
  • Diagnosis and treatment of insulin dependent diabetes mellitus
    Patent number: 5578303
    Abstract: A 65 KD heat shock protein, proteins cross-reactive therewith, antibodies thereto or T cells specific thereto can be used for detecting in humans the existence of, a tendency to develop, or the initiation of a process leading to insulin dependent diabetes mellitus. Antibodies to hsp65 can be used to detect the hsp65 molecule in blood or urine. The hsp65 molecule of any species, or any other substance immunologically cross-reactive therewith, when administered with a tolerogenic carrier, can be used for the prevention or treatment of IDDM prior to development of clinical symptoms thereof. T cells, active fragments thereof or the receptor peptide thereof can also be used for prevention or treatment of IDDM.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: November 26, 1996
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irun R. Cohen, Dana Elias, Doron Markovits
  • Diagnosis and treatment of insulin dependent diabetes mellitus
    Patent number: 5114844
    Abstract: A 65 KD heat shock protein, proteins cross-reactive therewith, or antibodies thereto can be used for detecting in humans the existence of, a tendency to develop, or the initiation of a process leading to insulin dependent diabetes mellitus. Antibodies to hsp65 can be used to detect the hsp65 molecule in blood or urine. The hsp65 molecule of any species, or any other substance immunologically cross-reactive therewith, when administered with a tolerogenic carrier, can be used for the prevention or treatment of IDDM prior to development of clinical symptoms thereof.
    Type: Grant
    Filed: June 26, 1989
    Date of Patent: May 19, 1992
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Irun R. Cohen, Dana Elias, Doron Markovits