Patents by Inventor Dorothea H. Scandella

Dorothea H. Scandella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid gene regulatory region operable in E. coli
    Patent number: 5162216
    Abstract: This invention is directed to a novel hybrid regulatory region for directing and regulating transcription and translation of a gene sequence positioned downstream from the hybrid regulatory region. This hybrid regulatory region includes the promoter sequence of the phage lambda P.sub.R promoter-operator region fused to the operator sequence of the phage lambda P.sub.L promoter-operator region.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: November 10, 1992
    Assignee: Enzon Labs Inc.
    Inventors: Dorothea H. Scandella, Keith H. McKenney
  • Recombinant Factor VIIIC fragments
    Patent number: 5149637
    Abstract: New fragments of the Factor VIII procoagulant protein (Factor VIIIC) are disclosed. These fragments have an Mr value of 88,000 d or 49,000 d or extend from amino acid residues 1974 to 2332 or 2052 to 2332. These fragments have use in the treatment of patients who have developed antibodies which inhibit Factor VIII.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: September 22, 1992
    Assignees: Scripps Clinic & Research Foundation, Rorer Biotechnology Inc.
    Inventors: Dorothea H. Scandella, William N. Drohan, Theodore S. Zimmerman, Carol A. Fulcher
  • Recombinant factor VIIIC derived fragments
    Patent number: 4980456
    Abstract: New fragments of the Factor VIII procoagulant protein (Factor VIIIC) are disclosed. These fragments have an Mr value of 88,000 d or 49,000 d or extend from amino acid residues 1974 to 2332 or 2052 to 2332. These fragments have use in the treatment of patients who have developed antibodies which inhibit Factor VIII.
    Type: Grant
    Filed: April 6, 1987
    Date of Patent: December 25, 1990
    Assignees: Scripps Clinic and Research Foundation, Rorer Biotechnology Inc.
    Inventors: Dorothea H. Scandella, William N. Drohan, Theodore S. Zimmerman, Carol A. Fulcher