Patents by Inventor DOROTHEA ROBEV

DOROTHEA ROBEV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADAM17 binding molecules and uses thereof
    Patent number: 12378321
    Abstract: The present invention provides various ADAM17 binding molecules (including antibodies and fragments thereof), compositions comprising such ADAM17 binding molecules, and methods of using such ADAM17 binding molecules and compositions, for example in inhibiting binding of ADAM17 to ADAM17 substrates (such as ErbB ligands), in inhibiting the proliferation of cancer cells, and in treating cancer.
    Type: Grant
    Filed: March 7, 2020
    Date of Patent: August 5, 2025
    Inventors: Dimitar Nikolov, Nayanendu Saha, Zhongyu Zhu, Dimiter Stanchev Dimitrov, Dorothea Robev, Thomas Edgeworth White
  • ADAM17 BINDING MOLECULES AND USES THEREOF
    Publication number: 20230159653
    Abstract: The present invention provides various ADAM17 binding molecules (including antibodies and fragments thereof), compositions comprising such ADAM17 binding molecules, and methods of using such ADAM17 binding molecules and compositions, for example in inhibiting binding of ADAM17 to ADAM17 substrates (such as ErbB ligands), in inhibiting the proliferation of cancer cells, and in treating cancer.
    Type: Application
    Filed: March 7, 2020
    Publication date: May 25, 2023
    Inventors: DIMITAR NIKOLOV, NAYANENDU SAHA, ZHONGYU ZHU, DIMITER STANCHEV DIMITROV, DOROTHEA ROBEV, THOMAS EDGEWORTH WHITE