Patents by Inventor Dorrit Aaslyng
Dorrit Aaslyng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7189553Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.Type: GrantFiled: December 6, 2002Date of Patent: March 13, 2007Assignee: Novozymes A/SInventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Norskov-Lauritsen, Ole Hvilsted Olsen, Merete Simonsen, Eric Castelijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
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Patent number: 6908991Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: GrantFiled: December 6, 2002Date of Patent: June 21, 2005Assignee: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjorn Petersen, Leif Norskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Publication number: 20050003986Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: ApplicationFiled: July 21, 2004Publication date: January 6, 2005Applicant: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Petersen, Leif Norskov-Lauridsen, Villy Jensen, Dorrit Aaslyng
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Patent number: 6835821Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: GrantFiled: December 5, 2002Date of Patent: December 28, 2004Assignee: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjorn Petersen, Leif Nørskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Patent number: 6808913Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: GrantFiled: November 27, 2002Date of Patent: October 26, 2004Assignee: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjørn Petersen, Leif Nørskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Patent number: 6632646Abstract: Enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.Type: GrantFiled: October 2, 2000Date of Patent: October 14, 2003Assignees: Novozymes A/S, Unilever PLC.Inventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Nørskov-Lauritsen, Ole Hvilsted Olsen, Merete Simonsen, Eric Casteleijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
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Publication number: 20030191039Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.Type: ApplicationFiled: December 6, 2002Publication date: October 9, 2003Applicant: Novozymes A/SInventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Norskov-Lauritsen, Ole Hvilsted, Merete Simonsen, Eric Casteleijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
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Publication number: 20030186378Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: ApplicationFiled: December 5, 2002Publication date: October 2, 2003Applicant: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjorn Petersen, Leif Norskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Publication number: 20030175933Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: ApplicationFiled: December 6, 2002Publication date: September 18, 2003Applicant: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjorn Petersen, Leif Norskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Publication number: 20030148495Abstract: The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.Type: ApplicationFiled: November 27, 2002Publication date: August 7, 2003Applicant: Novozymes A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjorn Petersen, Leif Norskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Patent number: 6506589Abstract: The present invention relates to mutations of the subtilisin gene, some of which result in changes in the chemical characteristics of subtilisin enzyme. Mutations are created at specific nucleic acids of the subtilisin gene and, in various specific embodiments, the mutant enzymes possess altered chemical properties including, but not limited to, increased stability to oxidation, augmented proteolytic activity, and improved washability. The present invention also relates, but is not limited to, the amino acid and DNA sequences for two proteases derived from Bacillus lentus variants, subtilisin 147 and subtilisin 309, as well as mutations of these genes and the corresponding mutant enzymes.Type: GrantFiled: June 7, 1995Date of Patent: January 14, 2003Assignee: Novozymes, A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bjørn Petersen, Leif Nørskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng
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Patent number: 6379653Abstract: The present invention provides safe products for bleaching teeth. Oral compositions comprising at least one oxidoreductase fulfil criteria without the presence of peroxide or with only very little peroxide present. The invention also relates to an oral care product comprising the oral composition of the invention, a method of bleaching teeth, a method for using said oral care products and the use of oxidoreductases for oxidation of teeth stains.Type: GrantFiled: August 27, 1999Date of Patent: April 30, 2002Assignee: Novozymes A/SInventors: Dorrit Aaslyng, Rie Tsuchiya, Abdul Gaffar, Sahar F. Smith
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Publication number: 20020028754Abstract: The invention provides an antimicrobial composition comprising an enzymatic component and one or more non-enzymatic biocides; a method for killing or inhibiting microbial cells comprising a treatment with the antimicrobial composition; and a detergent composition comprising the antimicrobial composition. The invention provides an improved antimicrobial effect.Type: ApplicationFiled: July 5, 2001Publication date: March 7, 2002Applicant: Novozymes A/SInventors: Charlotte Johansen, Dorrit Aaslyng
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Patent number: 6197567Abstract: Enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzyme exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.Type: GrantFiled: March 12, 1997Date of Patent: March 6, 2001Assignees: Novo Nordisk A/S, Unilever PLCInventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Nørskov-Lauritsen, Ole Hvilsted Olsen, Merete Simonsen, Eric Casteleijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
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Patent number: 5989526Abstract: The present invention provides safe products for bleaching teeth. Oral compositions comprising at least one oxidoreductase fulfil said criteria without the presence of peroxide or with only very little peroxide present. The invention also relates to an oral care product comprising the oral composition of the invention, a method of bleaching teeth, a method for using said oral care products and the use of oxidoreductases for oxidation of teeth stains.Type: GrantFiled: February 5, 1998Date of Patent: November 23, 1999Assignees: Novo Nordisk A/S, Colgate-Palmolive CompanyInventors: Dorrit Aaslyng, Rie Tsuchiya, Abdul Gaffar, Sahar F. Smith
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Patent number: 5985629Abstract: Contact lens are cleaned and disinfected by contacting with an enzyme that functions as a cleaning agent by degrading deposits on the lens, and with an enzyme inhibitor that inhibits remaining enzyme activity and a mild disinfecting agent. If rinsing of the lens is not carried out after cleaning and disinfecting, this procedure prevents eye damage by inhibiting remaining enzyme activity and using a mild disinfectant. Preferred enzymes are proteases such as an acidic aspartic protease, a cysteine protease, a serine protease or a metalloprotease, and preferred enzyme inhibitors function both as an inhibitor and as a mild disinfectant such as chloramine-T, chloramine-B, bacitracin or aryl boronic acids. In a preferred method, the enzyme is subtilisin A and the enzyme inhibitor and disinfectant is chloramine-T.Type: GrantFiled: February 12, 1997Date of Patent: November 16, 1999Assignee: Novo Nordisk A/SInventors: Dorrit Aaslyng, Jack Bech Nielsen, Lone Kierstein Nielsen
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Patent number: 5981243Abstract: The present invention relates to isolated nucleic acid constructs containing a sequence encoding a Myceliophthora laccase, and the laccase proteins encoded thereby.Type: GrantFiled: September 29, 1997Date of Patent: November 9, 1999Inventors: Randy Michael Berka, Stephen H. Brown, Feng Xu, Palle Schneider, Karen M. Oxenb.o slashed.ll, Dorrit A. Aaslyng
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Patent number: 5948121Abstract: The present invention relates to a permanent dyeing composition comprising a) above 0 to 1 mg enzyme protein per ml dyeing composition of microbial laccase, b) one or more dye precursor, and c) optionally one or more dye modifiers, the use of the dyeing composition for dyeing keratinous fibers, such as hair, fur, hide, and wool, and a method for permanent dyeing of keratinous fibers.Type: GrantFiled: May 22, 1998Date of Patent: September 7, 1999Assignee: Novo Nordisk A/SInventors: Dorrit Aaslyng, Niels Henrik S.o slashed.rensen, Karen R.o slashed.rb.ae butted.k
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Patent number: 5795760Abstract: The present invention relates to isolated nucleic acid constructs containing a sequence encoding a Myceliophthora laccase, and the laccase proteins encoded thereby.Type: GrantFiled: September 29, 1997Date of Patent: August 18, 1998Assignees: Novo Nordisk A/S, Novo Nordisk Biotech, Inc.Inventors: Randy Michael Berka, Stephen H. Brown, Feng Xu, Palle Schneider, Karen M. Oxenb.o slashed.ll, Dorrit A. Aaslyng
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Patent number: 5741694Abstract: The present invention relates to mutations of the subtilisin gene, some of which result in changes in the chemical characteristics of subtilisin enzyme. Mutations are created at specific nucleic acids of the subtilisin gene and, in various specific embodiments, the mutant enzymes possess altered chemical properties including, but not limited to, increased stability to oxidation, augmented proteolytic activity, and improved washability. The present invention also relates, but is not limited to, the amino acid and DNA sequences for two proteases derived from Bacillus lentus variants, subtilisin 147 and subtilisin 309, as well as mutations of these genes and the corresponding mutant enzymes.Type: GrantFiled: June 7, 1995Date of Patent: April 21, 1998Assignee: Novo Nordisk A/SInventors: Sven Hastrup, Sven Branner, Fanny Norris, Steffen Bj.o slashed.rn Petersen, Leif N.o slashed.rskov-Lauridsen, Villy Johannes Jensen, Dorrit Aaslyng