Patents by Inventor Dorte Kirstein

Dorte Kirstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinoline derivatives containing a diol as leukotriene antagonists
    Patent number: 5945433
    Abstract: The present invention relates to hitherto unknown compounds of formula (I) in which R.sub.1 is hydrogen or halogen, preferably fluorine or chlorine, and m is 0, 1 or 2. The present compounds are of value in the human and veterinary practice as leukotriene antagonists.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: August 31, 1999
    Assignee: Leo Pharmaceutical Products, Ltd. A/S
    Inventors: Dorte Kirstein, Schneur Rachlin
  • Isoserine derivatives and their use as leukotriene antagonists
    Patent number: 5576438
    Abstract: The present invention relates to hitherto unknown compounds of formula; Y stands for --CH.dbd.CH--; R.sub.1 is hydrogen or halogen, preferably fluorine, chlorine or bromine; R.sub.2 is halogen, preferably fluorine, chlorine or bromine, CH.sub.3, OCH.sub.3, NO.sub.2 or CF.sub.3, and n=0-3, preferably 0, 1 or 2; A stands for an acidic group, e.g. carboxy, 1-H-tetrazolyl or a hydroxamic acid group. The present compounds are of value in the human and veterinary practice as lipoxygenase inhibitors and/or leukotriene antagonists.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: November 19, 1996
    Assignee: Leo Pharmaceutical Products Ltd. A/S (L.o slashed.vens Kemiske Fabrik Produktionsaktiesel Skab)
    Inventors: Dorte Kirstein, Schneur Rachlin
  • Substituted quinolines and medicinal use thereof
    Patent number: 5110819
    Abstract: The present invention relates to hitherto unknown compounds of formula, in which formula R.sub.1 stands for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C.sub.1 --C.sub.8 --alkyl, aryl or for ar--C.sub.1 --C.sub.4 --alkyl, aryl or an being unsubstituted or substituted phenyl, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are the same or different and stand for hydrogen, halogen, pseudo halogen, cyano, nitro, amino, carboxy, carbalkoxy, carbamyl, hydroxy, alkyl, alkoxy; n and m are the same or different and stand for an integer from 0-6; provided that n cannot be zero when A stands for carboxy and X and Q both stand for a bond; X stands for a bond or for O, S, S(O), S(O).sub.2 or for NR.sub.8 where R.sub.8 is defined as R.sub.1 above; Q stands for a bond of for straight or branched, C.sub.1 --C.sub.6 --alkylene; A stands for an acidic group, e.g.
    Type: Grant
    Filed: June 1, 1990
    Date of Patent: May 5, 1992
    Assignee: Leo Pharmaceutical Products Ltd.
    Inventors: Ian Ahnfelt-Ronne, Erik T. Hansen, Dorte Kirstein, Ole Bent I. Nielsen, Schneur Rachlin