Patents by Inventor Dorte Strobaek

Dorte Strobaek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL POTASSIUM CHANNEL INHIBITORS
    Publication number: 20240034717
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising such compounds and their use for treating, alleviating or preventing diseases or disorders relating to the activity of potassium channels.
    Type: Application
    Filed: September 21, 2021
    Publication date: February 1, 2024
    Inventors: David Tristram BROWN, Palle CHRISTOPHERSEN, Thomas Amos JACOBSEN, Janus S. LARSEN, Pernille Hartveit POULSEN, Dorte STRØBAEK
  • NOVEL POTASSIUM CHANNEL INHIBITORS
    Publication number: 20220169602
    Abstract: The present invention relates to novel compounds, pharmaceutical compositions comprising such compounds and their use for treating, alleviating or preventing diseases or disorders relating to the activity of potassium channels.
    Type: Application
    Filed: March 20, 2020
    Publication date: June 2, 2022
    Inventors: David Tristram BROWN, Palle CHRISTOPHERSEN, Thomas Amos JACOBSEN, Janus S. LARSEN, Pernille Hartveit Poulsen, Dorte STRØBAEK
  • SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20120088780
    Abstract: This invention relates to novel substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as modulators of potassium channels. In other aspects the invention relates to the use of these compounds, in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: March 30, 2010
    Publication date: April 12, 2012
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Charlotte Hougaard, Dorte Strøbaek, Palle Christophersen
  • NOVEL 2-MORPHOLINO-3-AMIDO-PYRIDINE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20110312962
    Abstract: The present application discloses novel 2-morpholino-3-amido-pyhcline derivatives and their use as modulators of the voltage gated Kv7 (KCNQ) potassium ion channels in the treatment of pain, neurodegenerative disorders, urinary incontinence, etc. . . . . In other aspects the application discloses the use of these compounds, in a method for therapy and to pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: November 26, 2009
    Publication date: December 22, 2011
    Applicant: NEUROSEARCH A/S
    Inventors: William Dalby Brown, Carsten Jessen, Dorte Strøbaek
  • NOVEL 2,3-DIAMINO-QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20110269783
    Abstract: The present invention relates to novel 2,3-diamino-quinazolinone derivatives having medical utility, to use of the derivatives for the manufacture of a medicament, to pharmaceutical compositions comprising the derivatives, and to methods of treating a disorder, disease or a condition responsive to activation of Kv7 channels.
    Type: Application
    Filed: November 6, 2009
    Publication date: November 3, 2011
    Applicant: NEUROSEARCH A/S
    Inventors: Carsten Jessen, William Dalby Brown, Dorte Strøbaek
  • NOVEL 2-ETHYL-METHYL-AMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS
    Publication number: 20110003867
    Abstract: This invention relates to novel 2-ethyl-methyl-amino-3-amido-6-amino-pyridine derivatives having medical utility, to use of the 2-ethyl-methyl-amino-3-amido-6-amino-pyridine derivatives of the invention for the manufacture of a medicament, to pharmaceutical compositions comprising the 2-ethyl-methyl-amino-3-amido-6-amino-pyridine derivatives of the invention, and to methods of treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
    Type: Application
    Filed: December 10, 2008
    Publication date: January 6, 2011
    Applicant: NeuroSearch A/S
    Inventors: Carsten Jessen, William Dalby Brown, Dorte Strøbaek
  • NOVEL 2, 3-DIAMINO-QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20100160315
    Abstract: This invention relates to novel 2,3-diamino-quinazolinone derivatives having medical utility, to use of the 2,3-diamino-quinazolinone derivatives of the invention for the manufacture of a medicament, to pharmaceutical compositions comprising the 2,3-diamino-quinazolinone derivatives of the invention, and to methods of treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
    Type: Application
    Filed: May 22, 2008
    Publication date: June 24, 2010
    Applicant: Neuro Search A/S
    Inventors: Carsten Jessen, William Dalby Brown, Joachim Demnitz, Dorte Strobaek, Mads P.G. Korsgaard, Palle Christophersen
  • MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100099732
    Abstract: This invention relates to pharmaceutical compositions comprising phenylcarbamoyl-methyl-indole derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.
    Type: Application
    Filed: March 14, 2008
    Publication date: April 22, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Morten Grunnet, Palle Christophersen, David Spencer Jones, Elsebet Østergaard Nielsen, Dorte Strøbaek, Lars Siim Madsen
  • NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS
    Publication number: 20100087496
    Abstract: This invention relates to novel cinnamic amide derivatives that are found to be potent modulators of ion channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation of ion channels.
    Type: Application
    Filed: December 17, 2007
    Publication date: April 8, 2010
    Applicant: NeuroSearch A/S
    Inventors: Antonio Nardi, Morten Grunnet, Joachim Demnitz, Thomas Diness Jensen, Palle Christophersen, David Spencer Jones, Elsebet Ostergaard Nielsen, Dorte Strobaek, Lars Siim Madsen
  • NOVEL 2-AMINIO-PYRIDINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
    Publication number: 20100056584
    Abstract: This invention relates to novel 2-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: November 12, 2007
    Publication date: March 4, 2010
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm, Palle Christophersen
  • 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
    Publication number: 20100035951
    Abstract: This invention relates to 2-amino benzimidazole derivatives of Formula 1a or 1b: which are useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: July 5, 2007
    Publication date: February 11, 2010
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbaek, Tina Holm Johansen, Palle Christophersen
  • COMBINATIONS OF MONOAMINE REUPTAKE INHIBITORS AND POTASSIUM CHANNEL ACTIVATORS
    Publication number: 20090239880
    Abstract: This invention provides pharmaceutical compositions comprising therapeutically effective amounts of a monoamine reuptake inhibitor and an SK inhibitor. In another aspect the invention provides novel benzoimidazole derivatives for use according to the invention.
    Type: Application
    Filed: July 2, 2007
    Publication date: September 24, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen, John Paul Redrobe
  • Novel Pyrimidine-2,4-Diamine Derivatives and their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090124645
    Abstract: This invention relates to novel pyrimidine-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: October 13, 2006
    Publication date: May 14, 2009
    Applicant: NeuroSearch A/S
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL GUANIDINE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20090099208
    Abstract: This invention relates to novel guanidine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: March 22, 2007
    Publication date: April 16, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • 2-(Phenylamino) Benzimidazole Derivatives and Their Use as Modulators of Small- Conductance Calcuim-Activated Potassium Channels
    Publication number: 20090076106
    Abstract: This invention relates to novel 2-(phenylamino)benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 21, 2006
    Publication date: March 19, 2009
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Svane Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • Novel Quinazoline-2,4-Diamine Derivatives and Their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20090048278
    Abstract: This invention relates to novel quinazoline-2,4-diamine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 6, 2006
    Publication date: February 19, 2009
    Inventors: Ulrik Svane Sorensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Palle Christophersen
  • NOVEL QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20090036473
    Abstract: This invention relates to novel quinazolinone derivatives having medical utility, to use of the quinazolinone derivatives of the invention for the manufacture of a medicament, to pharmaceutical compositions comprising the quinazolinone derivatives of the invention, and to methods of treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
    Type: Application
    Filed: March 9, 2007
    Publication date: February 5, 2009
    Inventors: William Dalby Brown, Carsten Jessen, Joachim Demnitz, Tino Dyhring, Dorte Strobaek
  • Novel 2-Amino Benzimidazole Derivatives and Their Use As Modulators Of Small-Conductance Calcium-Activated Potassium Channels
    Publication number: 20080200529
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: January 10, 2006
    Publication date: August 21, 2008
    Applicant: NEURO SEARCH A/S
    Inventors: Ulrik Svane Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • Novel 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
    Publication number: 20070197618
    Abstract: This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: August 3, 2005
    Publication date: August 23, 2007
    Applicant: NEUROSEARCH A/S
    Inventors: Ulrik Sorensen, Lene Teuber, Dan Peters, Dorte Strobaek, Tina Johansen, Karin Nielsen, Palle Christophersen
  • Erg channel openers for the treatment of cardiac arrhythmias
    Publication number: 20060281794
    Abstract: This invention relates to the use of ERG channel openers for the treatment of cardiac arrhythmias, and to the use of specific compounds for such treatment. In a separate aspect the invention provides novel compounds useful as ERG channel openers.
    Type: Application
    Filed: September 6, 2004
    Publication date: December 14, 2006
    Inventors: Soren Olesen, Morten Grunnet, Palle Christophersen, Dorte Strobaek, Joachim Demnitz, Rie Hansen