Patents by Inventor Doru Petrisor

Doru Petrisor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12521102
    Abstract: An embodiment in accordance with the present invention provides a new biopsy needle that may address several problems identified with currently available biopsy needles. In short, the new needle has a straighter insertion path, no forward fire, lower noise, and is pneumatic power-assisted so that it can be operated with one hand. These features improve biopsy targeting, provide safer operation for the patient and personnel, reduce patient discomfort, and respectively make optional the help of an assistant at biopsy.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: January 13, 2026
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Changhan Jun, Doru Petrisor, Misop Han
  • Patent number: 12465336
    Abstract: An embodiment in accordance with the present invention provides a remote center of motion robot. The RCM here is a parallelogram bar type RCM mechanism with a novel joint arrangement. The novel joint arrangement facilitates the mounting of the medical instrument and offers improved clearance relative to the patient. Moreover, the robot was built to guide a bone biopsy cannula, needle, or drill. Even though exact interventional values are unknown, it is expected that the forces exerted laterally on the needle-guide are higher than those encountered for slender needle insertion into soft tissue. For this, the RCM has been built with novel structure to enhance stiffness.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: November 11, 2025
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor, Changhan Jun, Sunghwan Lim
  • Patent number: 12414800
    Abstract: An embodiment in accordance with the present invention provides a robot structure that includes an MM-Safe pneumatic stepper motor and optical encoding technologies. The present invention includes a needle guide and a needle depth limiter. The needle for biopsy is inserted through the needle guide and the depth of inserting is limited by the needle depth limiter. The robot is configured to control this procedure. The robot structure is adapted for biopsy, a novel way of setting the depth of needle insertion, image-to-robot registration. The system includes control for the robot.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: September 16, 2025
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor
  • Publication number: 20250195049
    Abstract: An embodiment in accordance with the present invention provides a new biopsy needle that may address several problems identified with currently available biopsy needles. In short, the new needle has a straighter insertion path, no forward fire, lower noise, and is pneumatic power-assisted so that it can be operated with one hand. These features improve biopsy targeting, provide safer operation for the patient and personnel, reduce patient discomfort, and respectively make optional the help of an assistant at biopsy.
    Type: Application
    Filed: March 6, 2025
    Publication date: June 19, 2025
    Inventors: Dan Stoianovici, Changhan Jun, Doru Petrisor, Misop Han
  • Patent number: 12007009
    Abstract: A novel way of mounting a harmonic drive gearhead to a cylindrically shaped motor reduces the overall size of the actuator assembly. Specifically, the motor is mounted within the harmonic drive and its bearings, a space that is typically occupied by a harmonic drive component. This is made possible by redesigning the harmonic drive such that it is able to surround the motor and provide for a compact footprint for the actuator assembly.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: June 11, 2024
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor
  • Publication number: 20230415344
    Abstract: Robot watchdog software is responsible for monitoring the state of the system and resulting motion and reformulating commands due to task changes and dynamic conditions. However, if the robot watchdog software slows down or stalls, the motion control board remains unsupervised and robotic motion may become hazardous. The addition of a hardware watchdog mitigates the likelihood of this hazard occurring. A hybrid software-hardware robot watchdog is described herein. A fail-safe robotic system is implemented with a two tier software-hardware check system: the software checks the robotic hardware and in turn a hardware watchdog checks the activity of the software.
    Type: Application
    Filed: October 12, 2021
    Publication date: December 28, 2023
    Inventors: Dan Stoianovici, Doru Petrisor
  • Publication number: 20230356001
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including Mill. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Application
    Filed: July 18, 2023
    Publication date: November 9, 2023
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 11745027
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: September 5, 2023
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Publication number: 20220373073
    Abstract: A novel way of mounting a harmonic drive gearhead to a cylindrically shaped motor reduces the overall size of the actuator assembly. Specifically, the motor is mounted within the harmonic drive and its bearings, a space that is typically occupied by a harmonic drive component. This is made possible by redesigning the harmonic drive such that it is able to surround the motor and provide for a compact footprint for the actuator assembly.
    Type: Application
    Filed: November 2, 2020
    Publication date: November 24, 2022
    Inventors: Dan Stoianovici, Doru Petrisor
  • Publication number: 20220330982
    Abstract: An embodiment in accordance with the present invention provides a robot structure that includes an MM-Safe pneumatic stepper motor and optical encoding technologies. The present invention includes a needle guide and a needle depth limiter. The needle for biopsy is inserted through the needle guide and the depth of inserting is limited by the needle depth limiter. The robot is configured to control this procedure. The robot structure is adapted for biopsy, a novel way of setting the depth of needle insertion, image-to-robot registration. The system includes control for the robot.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 20, 2022
    Inventors: Dan Stoianovici, Doru Petrisor
  • Patent number: 11439434
    Abstract: An embodiment in accordance with the present invention provides a robot structure that includes an MRI-Safe pneumatic stepper motor and optical encoding technologies. The present invention includes a needle guide and a needle depth limiter. The needle for biopsy is inserted through the needle guide and the depth of inserting is limited by the needle depth limiter. The robot is configured to control this procedure. The robot structure is adapted for biopsy, a novel way of setting the depth of needle insertion, image-to-robot registration. The system includes control for the robot.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: September 13, 2022
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor
  • Publication number: 20210369253
    Abstract: An embodiment in accordance with the present invention provides a remote center of motion robot. The RCM here is a parallelogram bar type RCM mechanism with a novel joint arrangement. The novel joint arrangement facilitates the mounting of the medical instrument and offers improved clearance relative to the patient. Moreover, the robot was built to guide a bone biopsy cannula, needle, or drill. Even though exact interventional values are unknown, it is expected that the forces exerted laterally on the needle-guide are higher than those encountered for slender needle insertion into soft tissue. For this, the RCM has been built with novel structure to enhance stiffness.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 2, 2021
    Inventors: Dan Stoianovici, Doru Petrisor, Changhan Jun, Sunghwan Lim
  • Publication number: 20210128122
    Abstract: An embodiment in accordance with the present invention provides a new biopsy needle that may address several problems identified with currently available biopsy needles. In short, the new needle has a straighter insertion path, no forward fire, lower noise, and is pneumatic power-assisted so that it can be operated with one hand. These features improve biopsy targeting, provide safer operation for the patient and personnel, reduce patient discomfort, and respectively make optional the help of an assistant at biopsy.
    Type: Application
    Filed: February 22, 2018
    Publication date: May 6, 2021
    Inventors: Dan Stoianovici, Changhan Jun, Doru Petrisor, Misop Han
  • Publication number: 20210116447
    Abstract: An embodiment in accordance with the present invention provides a method and device that leverages a controlled scanning process for CTC-antibody binding, rather than classic random mixing. Magnetophoretic direct extraction is used to extract the CTCs onto a standard microscope slide. A device according to the present invention includes a vial into which a CTC bearing solution is combined with antibody-bound-PMP beads. An electromagnet is used to apply a magnetic field to engage the beads along the magnetic lines across the vial. The magnetic field and in turn the beads are moved on a fine pitch helical trajectory. The entire volume of the vial is scanned in this manner, allowing beads to come into close proximity to any CTCs present, and to collect all of the CTCs in the vial.
    Type: Application
    Filed: November 29, 2018
    Publication date: April 22, 2021
    Inventors: Dan Stoianovici, Doru Petrisor, Changhan Jun, Kenneth J. Pienta
  • Publication number: 20200315658
    Abstract: An embodiment in accordance with the present invention provides a robot structure that includes an MRI-Safe pneumatic stepper motor and optical encoding technologies. The present invention includes a needle guide and a needle depth limiter. The needle for biopsy is inserted through the needle guide and the depth of inserting is limited by the needle depth limiter. The robot is configured to control this procedure. The robot structure is adapted for biopsy, a novel way of setting the depth of needle insertion, image-to-robot registration. The system includes control for the robot.
    Type: Application
    Filed: May 23, 2017
    Publication date: October 8, 2020
    Inventors: Dan Stoianovici, Doru Petrisor
  • Patent number: 10646295
    Abstract: Featured is a medical instrument driver, a robotic apparatus embodying such a medical instrument driver and methods related thereto for inserting a medical instrument into tissue of a mammal (e.g., human). Such medical instruments include medical needles, biopsy needles, trocars, cutters and introducers. Such a medical instrument driver according to the present invention is configured and arranged so that medical instrument is rotated as it is being moved longitudinally for insertion into the tissue such that the medical instrument is spiraling as it pierces and traverses the tissue to the target area.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: May 12, 2020
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Doru Petrisor, Dumitru Mazilu, Alexandru Patriciu, Lucian Gruionu
  • Publication number: 20200086140
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Application
    Filed: May 2, 2019
    Publication date: March 19, 2020
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Patent number: 10315046
    Abstract: Featured is a robot and a needle delivery apparatus. Such a robot comprises a plurality of actuators coupled to control locating any of number of intervention specific medical devices such as intervention specific needle injectors. Such a robot is usable with image guided interventions using any of a number of types of medical imaging devices or apparatuses including MRI. The end-effector can include an automated low needle delivery apparatus that is configured for dose radiation seed brachytherapy injection. Also featured is an automated seed magazine for delivering seeds to such an needle delivery apparatus adapted for brachytherapy seed injection.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: June 11, 2019
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Alexandru Patriciu, Dumitru Mazilu, Doru Petrisor, Louis R. Kavoussi
  • Publication number: 20190142396
    Abstract: An embodiment in accordance with the present invention provides a remote center of motion robot. The RCM here is a parallelogram bar type RCM mechanism with a novel joint arrangement. The novel joint arrangement facilitates the mounting of the medical instrument and offers improved clearance relative to the patient. Moreover, the robot was built to guide a bone biopsy cannula, needle, or drill. Even though exact interventional values are unknown, it is expected that the forces exerted laterally on the needle-guide are higher than those encountered for slender needle insertion into soft tissue. For this, the RCM has been built with novel structure to enhance stiffness.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 16, 2019
    Inventors: Dan Stoianovici, Doru Petrisor, Changhan Jun, Sunghwan Lim
  • Patent number: 10159469
    Abstract: An embodiment in accordance with the present invention provides a device and method for a transrectal ultrasound (TRUS) guided prostate biopsy. The device includes an ultrasound wand equipped with a lateral fire ultrasound sensor. The ultrasound wand also defines a channel having an oblique path though the wand. The channel accommodates a biopsy needle, which can be pivoted as well inserted through the channel to different depths in order to perform a biopsy of the prostate. The device therefore uses only three degrees-of-freedom of movement in order to obtain the biopsy samples. Additionally, the ultrasound wand can be used to generate a three-dimensional image of the prostate.
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: December 25, 2018
    Assignee: The Johns Hopkins University
    Inventors: Dan Stoianovici, Misop Han, Doru Petrisor, Chunwoo Kim