Patents by Inventor Doruk Tayli
Doruk Tayli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11614509Abstract: During operation, a computer system may acquire magnetic resonance (MR) signals associated with a sample from a measurement device or memory. Then, the computer system may access a predetermined set of coil magnetic field basis vectors associated with a surface surrounding the sample, where coil sensitivities of coils in the measurement device are represented by weighted superpositions of the predetermined set of coil magnetic field basis vectors using coefficients, and where the predetermined coil magnetic field basis vectors are solutions to Maxwell's equations. Next, the computer system may solve, on a voxel-by-voxel basis for voxels associated with the sample, a nonlinear optimization problem for MR information associated with the sample and the coefficients using: a forward model that uses the MR information as inputs and simulates response physics of the sample, the MR signals and the predetermined set of coil magnetic field basis vectors.Type: GrantFiled: June 21, 2021Date of Patent: March 28, 2023Assignee: Q Bio, Inc.Inventors: Matteo Alessandro Francavilla, Jorge Fernandez Villena, Stamatios Lefkimmiatis, Athanasios Polymeridis, Doruk Tayli
-
Publication number: 20220308136Abstract: A system may measure a response associated with a sample to an excitation. The system may compute, using the measured response and the excitation as inputs to an inverse model or a predetermined predictive model, model parameters on a voxel-by-voxel basis in a forward model with multiple voxels that represent the sample. The predetermined predictive model was trained using training data for different excitation strengths, different measurement conditions, or both. The forward model may simulate response physics occurring within the sample to a given excitation, and the model parameters may include magnetic susceptibilities of the multiple voxels. Moreover, the system may determine an accuracy of the model parameters by comparing at least the measured response and a calculated predicted value of the response using the forward model, the model parameters and the excitation. When the accuracy exceeds a predefined value, the system may provide the model parameters as an output.Type: ApplicationFiled: June 3, 2022Publication date: September 29, 2022Inventors: Doruk Tayli, Stamatis Lefkimmiatis, Athanasios Polymeridis
-
Patent number: 11360166Abstract: A system may measure, using a measurement device, a response associated with a sample to an excitation. Then, the system may compute, using the measured response and the excitation as inputs to one of an inverse model and a predetermined predictive model, model parameters on a voxel-by-voxel basis in a forward model with multiple voxels that represent the sample. The forward model may simulate response physics occurring within the sample to a given excitation, and the model parameters may include magnetic susceptibilities of the multiple voxels. Moreover, the system may determine an accuracy of the model parameters by comparing at least the measured response and a calculated predicted value of the response using the forward model, the model parameters and the excitation. When the accuracy exceeds a predefined value, the system may provide the model parameters as an output to: a user, another electronic device, a display, and/or a memory.Type: GrantFiled: June 20, 2019Date of Patent: June 14, 2022Assignee: Q Bio, IncInventors: Doruk Tayli, Stamatios Lefkimmiatis, Athanasios Polymeridis
-
Publication number: 20210311151Abstract: During operation, a computer system may acquire magnetic resonance (MR) signals associated with a sample from a measurement device or memory. Then, the computer system may access a predetermined set of coil magnetic field basis vectors associated with a surface surrounding the sample, where coil sensitivities of coils in the measurement device are represented by weighted superpositions of the predetermined set of coil magnetic field basis vectors using coefficients, and where the predetermined coil magnetic field basis vectors are solutions to Maxwell's equations. Next, the computer system may solve, on a voxel-by-voxel basis for voxels associated with the sample, a nonlinear optimization problem for MR information associated with the sample and the coefficients using: a forward model that uses the MR information as inputs and simulates response physics of the sample, the MR signals and the predetermined set of coil magnetic field basis vectors.Type: ApplicationFiled: June 21, 2021Publication date: October 7, 2021Inventors: Matteo Alessandro Francavilla, Jorge Fernandez Villena, Stamatios Lefkimmiatis, Athanasios Polymeridis, Doruk Tayli
-
Patent number: 11131735Abstract: A computer that determines coefficients in a representation of coil sensitivities and MR information associated with a sample is described. During operation, the computer may acquire MR signals associated with a sample from the measurement device. Then, the computer may access a predetermined set of coil magnetic field basis vectors, where weighted superpositions of the predetermined set of coil magnetic field basis vectors using the coefficients represent coil sensitivities of coils in the measurement device, and where the predetermined coil magnetic field basis vectors are solutions to Maxwell's equations. Next, the computer may solve a nonlinear optimization problem for the MR information associated with the sample and the coefficients using the MR signals and the predetermined set of coil magnetic field basis vectors.Type: GrantFiled: September 25, 2020Date of Patent: September 28, 2021Assignee: Q Bio, Inc.Inventors: Jorge Fernandez Villena, Stamatios Lefkimmiatis, Athanasios Polymeridis, Doruk Tayli
-
Publication number: 20210096203Abstract: A computer that determines coefficients in a representation of coil sensitivities and MR information associated with a sample is described. During operation, the computer may acquire MR signals associated with a sample from the measurement device. Then, the computer may access a predetermined set of coil magnetic field basis vectors, where weighted superpositions of the predetermined set of coil magnetic field basis vectors using the coefficients represent coil sensitivities of coils in the measurement device, and where the predetermined coil magnetic field basis vectors are solutions to Maxwell's equations. Next, the computer may solve a nonlinear optimization problem for the MR information associated with the sample and the coefficients using the MR signals and the predetermined set of coil magnetic field basis vectors.Type: ApplicationFiled: September 25, 2020Publication date: April 1, 2021Inventors: Jorge Fernandez Villena, Stamatios Lefkimmiatis, Athanasios Polymeridis, Doruk Tayli
-
Publication number: 20200264249Abstract: A system may measure, using a measurement device, a response associated with a sample to an excitation. Then, the system may compute, using the measured response and the excitation as inputs to one of an inverse model and a predetermined predictive model, model parameters on a voxel-by-voxel basis in a forward model with multiple voxels that represent the sample. The forward model may simulate response physics occurring within the sample to a given excitation, and the model parameters may include magnetic susceptibilities of the multiple voxels. Moreover, the system may determine an accuracy of the model parameters by comparing at least the measured response and a calculated predicted value of the response using the forward model, the model parameters and the excitation. When the accuracy exceeds a predefined value, the system may provide the model parameters as an output to: a user, another electronic device, a display, and/or a memory.Type: ApplicationFiled: June 20, 2019Publication date: August 20, 2020Applicant: Q Bio, IncInventors: Doruk Tayli, Stamatis Lefkimmiatis, Athanasios Polymeridis