Patents by Inventor Doug Taylor
Doug Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9827117Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.Type: GrantFiled: April 25, 2014Date of Patent: November 28, 2017Assignee: Micell Technologies, Inc.Inventors: Doug Taylor, Jim McClain, Clint Smoke, Mike Cole, James DeYoung
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Patent number: 9539593Abstract: A stent holder for mounting and electrically charging a stent during coating of the stent using dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. An assembly for supporting and electrically charging a stent during the coating of the stent using dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. A chamber for creating an electrical field around a stent and for supporting, electrically charging, and exposing the stent to dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. A method for creating an electrical field around a stent and for supporting, electrically charging, and exposing the stent to dry particles comprising inert polymers, pharmaceutical or biological agents is provided.Type: GrantFiled: October 23, 2007Date of Patent: January 10, 2017Assignee: Micell Technologies, Inc.Inventors: James B. McClain, Doug Taylor, Ed Dickinson, Steve Worm
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Publication number: 20150112424Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.Type: ApplicationFiled: August 29, 2014Publication date: April 23, 2015Inventors: James DeYoung, Doug Taylor, Jim McClain, Clint Smoke, Mike Cole
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Publication number: 20150025620Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.Type: ApplicationFiled: April 25, 2014Publication date: January 22, 2015Applicant: Micell Technologies, Inc.Inventors: Doug Taylor, Jim McClain, Clint Smoke, Mike Cole, James DeYoung
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Patent number: 8852625Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.Type: GrantFiled: April 26, 2007Date of Patent: October 7, 2014Assignee: Micell Technologies, Inc.Inventors: James DeYoung, Doug Taylor, Jim McClain, Clint Smoke, Mike Cole
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Patent number: 8842040Abstract: A phased array antenna includes a plurality of subarrays, and each subarray includes a panel, a plurality of primary antenna elements positioned on the panel, and at least one pair of sensor antenna elements positioned along a perimeter of the panel. One of the sensor antenna elements is a transmitting sensor antenna element and the other sensor antenna element is a receiving sensor antenna element. Changes in the mutual coupling between the two high frequency sensor antenna elements as a function of deformation of the subarrays provides a calibration signal outside of the operational band of the array while the array is operated and without requiring external calibration sources.Type: GrantFiled: May 16, 2011Date of Patent: September 23, 2014Assignee: The United States of America, as represented by the Secretary of the NavyInventors: W Mark Dorsey, Rashmi Mital, Mark G Parent, Doug Taylor
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Patent number: 8834913Abstract: A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane derivative coating. An implantable stent device including a stent core having an oxidized surface with a layer of silane derivative covalently bonded thereto. A spacer layer comprising polyethylene glycol (PEG) is covalently bonded to the layer of silane derivative and a protein is covalently bonded to the PEG. A method of making a medical implant device including providing a substrate having a surface, oxidizing the surface and reacting with derivitized silane to form a silane coating covalently bonded to the surface. A bioactive agent is then covalently bonded to the silane coating. In particular instances, an additional coating of bio-absorbable polymer and/or pharmaceutical agent is deposited over the bioactive agent.Type: GrantFiled: December 28, 2009Date of Patent: September 16, 2014Assignee: Battelle Memorial InstituteInventors: Wendy J. Shaw, Clement R. Yonker, John L. Fulton, Barbara J. Tarasevich, James B. McClain, Doug Taylor
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Patent number: 8758429Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.Type: GrantFiled: September 6, 2012Date of Patent: June 24, 2014Assignee: Micell Technologies, Inc.Inventors: Doug Taylor, Jim McClain, Clint Smoke, Mike Cole, James DeYoung
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Publication number: 20130109270Abstract: An expander has a collapsed configuration and a deployed configuration. The expander has at least one expander component that is movably coupled to another expander component. The expander may be used with a toy figure. In one implementation, each of the expander components is pivotally coupled to another expander component. The expander includes a biasing member that biases adjacent expander components away from each other.Type: ApplicationFiled: January 10, 2012Publication date: May 2, 2013Inventors: Ruben Martinez, Steed Sun, Doug Taylor
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Publication number: 20130006351Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.Type: ApplicationFiled: September 6, 2012Publication date: January 3, 2013Applicant: MICELL TECHNOLOGIES, INC.Inventors: Doug Taylor, Jim McClain, Clint Smoke, Mike Cole, James DeYoung
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Patent number: 8298565Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto the substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming the coating; and sintering the coating under conditions that do not substantially modify the morphology of the pharmaceutical agent.Type: GrantFiled: July 14, 2006Date of Patent: October 30, 2012Assignee: Micell Technologies, Inc.Inventors: Doug Taylor, Jim McClain, Clint Smoke, Mike Cole, James DeYoung
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Patent number: 8106169Abstract: This invention provides for the plant production of immunoglobulins, wherein at least a portion of the glycans attached to the immunoglobulins lack fucose. The invention also provides the constructs; plasmids; vectors; transformed plant cells, transformed plant calli; transformed plant tissues (e.g., leaves, seeds, tubers, etc.); transformed whole plants used to produce such immunoglobulins; methods of producing the immunoglobulins; the immunoglobulins produced by the disclosed methods; and the use of such immunoglobulins.Type: GrantFiled: November 28, 2003Date of Patent: January 31, 2012Assignee: Phyton Holdings, LLCInventors: Kristen Briggs, Todd Glancy, Mich B. Hein, Andrew C. Hiatt, Anton S. Karnoup, W. H. Kerr Anderson, Dayakar Pareddy, Joseph Petolino, Beth Rubin-Wilson, Doug Taylor, Jean L. Roberts
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Publication number: 20110159069Abstract: A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane derivative coating. An implantable stent device including a stent core having an oxidized surface with a layer of silane derivative covalently bonded thereto. A spacer layer comprising polyethylene glycol (PEG) is covalently bonded to the layer of silane derivative and a protein is covalently bonded to the PEG. A method of making a medical implant device including providing a substrate having a surface, oxidizing the surface and reacting with derivitized silane to form a silane coating covalently bonded to the surface. A bioactive agent is then covalently bonded to the silane coating. In particular instances, an additional coating of bio-absorbable polymer and/or pharmaceutical agent is deposited over the bioactive agent.Type: ApplicationFiled: December 28, 2009Publication date: June 30, 2011Inventors: Wendy J. Shaw, Clement R. Yonker, John L. Fulton, Barbara J. Tarasevich, James B. McClain, Doug Taylor
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Patent number: 7907690Abstract: An interference cancellation (IC) system and method for use within a 1553 communication system comprising a data bus carrying primary signals having a 1553 component and a non-1553 component are provided. The IC system has an input port, a 1553 data extraction block and an interference cancellation circuit with an interference measurement and a cancellation block. The interference measurement block receives 1553 decoded data from the 1553 data extraction block and a sampled primary signal via the input port, and, within an impulse response block, produces an interference signal based on a 1553 impulse response system model. The cancellation block subtracts the interference signal from the sampled primary signal and produces an output signal with the 1553 component substantially cancelled. Furthermore, an IC system using adaptive filtering techniques within the impulse response block is provided. The Least Mean Squares (LMS) algorithm can be used as an adaptive filter technique.Type: GrantFiled: October 17, 2006Date of Patent: March 15, 2011Assignee: Edgewater Computer Systems, Inc.Inventors: Doug Taylor, John Fanson, George Price, Tooraj Esmailian, Laszlo Hazy
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Publication number: 20100063580Abstract: A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framework to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.Type: ApplicationFiled: January 8, 2008Publication date: March 11, 2010Inventors: James B. McClain, Doug Taylor, Robert Rabiner
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Patent number: 7592035Abstract: A method of coating a substrate comprises the steps of: (a) providing a substrate in an enclosed vessel, the substrate having a surface portion; (b) at least partially filling the enclosed vessel with a first supercritical fluid so that said first supercritical fluid contacts the surface portion, with the first supercritical fluid carrying or containing a coating component; then (c) adding a separate compressed gas atmosphere to the reaction vessel so that a boundary is formed between the first supercritical fluid and the separate compressed gas atmosphere, said separate compressed gas atmosphere having a density less than said first supercritical fluid; and then (d) displacing said first supercritical fluid from said vessel by continuing adding said separate compressed gas atmosphere to said vessel so that said boundary moves across said surface portion and a thin film of coating component is deposited on said microelectronic substrate.Type: GrantFiled: October 28, 2005Date of Patent: September 22, 2009Assignee: Micell Technologies, Inc.Inventors: James P. DeYoung, James B. McClain, Stephen M. Gross, Doug Taylor, Mark I. Wagner, David Brainard
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Publication number: 20090186069Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.Type: ApplicationFiled: April 26, 2007Publication date: July 23, 2009Applicant: MICELL TECHNOLOGIES, INC.Inventors: James DeYoung, Doug Taylor, Jim McClain, Clint Smoke, Mike Cole
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Patent number: 7546368Abstract: Systems and methods are provided for isolating performance variation in website monitoring. A set of geographically diverse monitoring agents are identified and a subset of baseline agents is selected from these monitoring agents. The baseline agents are those agents that are geographically close to the target website or otherwise enjoy reliable communications with the target website and are therefore less affected by network latencies. The frequency at which a target website is monitored is weighted in favor of the baseline agents in order to get an accurate baseline metric for the target website while also obtaining information regarding global accessibility of the website from the geographically disperse monitoring agents. The variations in sample frequency can be optimized for each particular set of baseline agents. The set of baseline agents can be pre-assigned or dynamically identified based on an analysis of the performance variation from each of the monitoring agents.Type: GrantFiled: June 1, 2005Date of Patent: June 9, 2009Assignee: NeuStar, Inc.Inventors: Timothy Drees, Lenny Rachitsky, Doug Taylor
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Publication number: 20090123515Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.Type: ApplicationFiled: July 14, 2006Publication date: May 14, 2009Inventors: Doug Taylor, Jim McClain, Clint Smoke, Mike Cole, James DeYoung
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Publication number: 20090062909Abstract: A coated coronary stent, comprising: a stainless steel sent framework coated with a primer layer of Parylene C; and a rapamycin-polymer coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially uniformly dispersed within the rapamycin-polymer coating.Type: ApplicationFiled: July 14, 2006Publication date: March 5, 2009Applicant: Micell Technologies, Inc.Inventors: Doug Taylor, James Deyoung, Jim McCain