Abstract: Embodiments disclosed herein include playback devices configured to operate in one or more playback configurations including configurations individual playback devices play back one or more corresponding channels of multichannel audio content. An audio parameter can be determined based on a distance between playback devices. In some examples, the audio parameter comprises a filter such as a low frequency filter that varies based on at least the distance between the playback devices. After the audio parameter is determined, the playback devices can play back audio content according to the determined audio parameter.

Abstract: Provided herein are methods of treating cancer, an infectious disease, or an infection, which comprise administering to a human patient in need thereof: (a) a TIGIT antagonist; (b) a PD-1 antagonist; and (c) lenvatinib represented by Formula (I), or a pharmaceutically acceptable salt thereof. Also provided are kits containing such agents and uses of therapeutic combinations of such agents for the treatment of cancer, an infectious disease, or an infection.

Abstract: Embodiments disclosed herein include playback devices configured to operate in one or more playback configurations including configurations individual playback devices play back one or more corresponding channels of multichannel audio content. An audio parameter can be determined based on a distance between playback devices. In some examples, the audio parameter comprises a filter such as a low frequency filter that varies based on at least the distance between the playback devices. After the audio parameter is determined, the playback devices can play back audio content according to the determined audio parameter.

Abstract: Compositions comprising donor cells, acceptor cells, and methods involving the same are described herein. In some embodiments, the donor cell is deficient in at least one endogenous function, for instance cytotoxic activity. In some embodiments, the donor cell comprises a T cell receptor (TCR) and a cargo, and the acceptor cell comprises an MHC. In some embodiments, the TCR facilitates transfer of the cargo to the acceptor cell. In some embodiments, the donor cell comprises a chimeric antigen receptor (CAR) and a cargo, and the acceptor cell comprises an antigen bound by the CAR. In some embodiments, the CAR facilitates transfer of the cargo to the acceptor cell.

Abstract: A glass manufacturing apparatus includes a forming apparatus defining a travel path extending in a travel direction. The forming apparatus conveys a ribbon of glass-forming material along the travel path in the travel direction of the forming apparatus. The glass manufacturing apparatus includes a cooling tube extending substantially parallel to the travel path and extending across the travel direction. The cooling tube includes a plurality of orifices spaced apart along the cooling tube and facing the travel path. Methods of manufacturing glass can comprise flowing a coolant from an outlet of a conduit in a direction toward a target location of a flowing ribbon of molten material. Methods can also include changing a phase of the coolant while the coolant is flowing towards the target location. The change in phase can cool the target location.

Abstract: A multi-point sliding door lock includes a lock assembly and a cartridge assembly, the lock assembly is configured to receive the cartridge assembly in a plurality of different positions spaced along a longitudinal axis. The lock assembly includes a lock housing supporting a pair of latch elements configured to move between an extended position and a retracted position. A slide plate is disposed within the lock housing and engaged with the pair of latch elements such that sliding movement of the slide plate pivots each of the pair of latch elements. The cartridge assembly includes a cartridge housing insertable at least partially into the lock housing. A hub is rotatably mounted at least partially within the cartridge housing. The hub engages with the slide plate when the cartridge assembly is received by the lock assembly such that rotation of the hub drives the sliding movement of the slide plate.

Abstract: A particulate filter having a honeycomb structure of a matrix of interconnected porous walls including inlet cells and outlet cells defining a plurality of inlet channels and outlet channels, respectively, wherein at least a portion of the outlet cells are larger than any of the inlet cells, and a cross-sectional shape of at least some of the outlet channels is rectangular. Honeycomb extrusion dies, honeycomb bodies, honeycomb structures, and methods of manufacture are described, as are other aspects.

Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: A data intake and query system can manage the search of data stored at an external location relative to the data intake and query system using one or more indexers. The data intake and query system can receive data stored at the external location. The data intake and query system can process the data and generate an index using the one or more indexers. The data intake and query system can discard the data and store the index and a location identifier of the external location in one or more buckets. In response to a query, the data intake and query system can identify that at least a subset of the data is responsive to the query using the index and can obtain the at least the subset of the data from the external location using the location identifier.

Abstract: One example of an IP KVM device includes a USB port, a display port, a communication port, a network port, and a processor communicatively coupled to the USB port, display port, communication port, and network port. The USB port may be communicatively coupled to a host device to receive first USB signals from the host device. The display port may be communicatively coupled to the host device to receive first display signals from the host device. The communication port may be communicatively coupled to a secondary IP KVM device to receive second USB signals from the host device and second display signals from the host device. The network port may be communicatively coupled to a network. The processor is to aggregate the first and second USB signals and the first and second display signals and output the aggregated USB signals and display signals via the network port.

Abstract: A vehicle battery terminal clamp assembly features a clasping mechanism and a securement assembly. The clasping mechanism includes a top wall with an upper battery post aperture and an upper slit, a bottom wall with a lower battery post aperture and a lower slit, and a front wall integrally extending between the top and bottom walls and including a front slit, and wherein the upper slit, the lower slit, and the front slit are arranged to form a continuous slit that extends from the upper battery post aperture, across the front wall and to the lower battery post aperture. The upper and lower battery post apertures are configured to receive an extent of a post extending from the vehicle battery. The securement assembly applies less than a nominal compressive force on the clasping mechanism, wherein the top wall of the clasping mechanism is substantially parallel with the bottom wall of the clasping mechanism.

Abstract: A CVD single crystal diamond having a smallest linear dimension of no less than 3.5 mm, a concentration of single substitutional nitrogen atoms in their neutral charge state (Ns0), as measured by EPR, of between 20 and 250 ppb, a hue angle, hab, between 75 and 135°.

Abstract: In one example, a system includes a semiconductor package having a metal contact. The system includes a metal submount. The metal submount includes a plurality of spring pin connectors embedded in the metal submount, the plurality of spring pin connectors being thermally and electrically connected to one another through the metal submount. The metal contact of the semiconductor package is thermally and electrically coupled to the metal submount through the plurality of spring pin connectors.

Abstract: A single photon avalanche diode (SPAD) device is presented. The SPAD device comprising: a Si-based avalanche layer formed over an n-type semiconductor contact layer; a p-type charge sheet layer formed in or on the avalanche layer, the p-type charge sheet layer having an in-plane width; a Ge-based absorber layer, formed over the charge sheet layer and/or the avalanche layer, and overlapping the charge sheet layer, the Ge-based absorber layer having an in-plane width; wherein, at least in one in-plane direction, the in-plane width of the Ge-based absorber layer is greater than the in-plane width of the p-type charge sheet layer.

Abstract: End launch termination devices are shown and disclosed. In one embodiment, the device includes a housing, a first clamp fixedly attached to the housing, and a second clamp opposed to the first clamp and movably attached to at least one of the first clamp or the housing, the first and second clamps defining a gap therebetween to receive a test substrate. The device additionally includes a conductor received in the cavity and fixedly attached to the housing, a center pin attached to the conductor and extending into the gap, and a rod resistor received in the cavity, attached to the conductor, and extending out of the housing.

Abstract: The invention is directed to a hydratable concentrated surfactant composition. The composition is pourable, easy to dilute, substantially free of sulfate and oil, comprises a C6-C14 acid, alcohol, amide or mixture thereof, anionic surfactant and an amphoteric surfactant, zwitterionic surfactant or both. The composition is in lamellar phase and thickens and transforms to an isotropic phase upon dilution. The composition comprises a mono-, di and/or tri-ester, can be used as a concentrate in small volumes and diluted as used and needed or can be diluted with water in refill packaging to ensure a reduction in plastic waste.

Abstract: A smoking cartridge configured to removably engage with the bowl of a smoking apparatus comprises a receptacle, a sealing member, and an opening that comprises inwardly projecting flaps. The receptacle is configured to contain a smoking material. The sealing member is disposed along the periphery of the receptacle proximal to a lower portion of the receptacle. The sealing member is configured to removably engage and seal with the bowl of the smoking apparatus. The opening is disposed at a bottom of the receptacle, which is defined by inwardly projecting adjustable flaps. The flaps are configured to be adjustably bent to vary the size of the opening.

Abstract: The invention is directed to a hydratable concentrated surfactant composition. The composition is pourable, easy to dilute, substantially free of sulfate and oil, comprises a C6-C14 acid, alcohol, amide or mixture thereof, anionic surfactant and an amphoteric surfactant, zwitterionic surfactant or both. The composition is in lamellar phase and thickens and transforms to an isotropic phase upon dilution. The composition comprises a hydroxyfunctionalized compound, can be used as a concentrate in small volumes and diluted as used and needed or can be diluted with water in refill packaging to ensure a reduction in plastic waste.

Abstract: A thermal control system is provided for monitoring and maintaining the temperature of a fluid sample within a cartridge having a plurality of wells. The thermal control system includes a heater block assembly having a cartridge slot sized and shaped to receive the cartridge within the heater block assembly. The heater block assembly is comprised of thermally conductive material. The thermal control system also includes a printed circuit board assembly coupled to the heater block assembly. The printed circuit board assembly is configured to generate heat and deliver the heat to the heater block assembly. The heater block assembly is configured to distribute the heat to the fluid sample located within the wells of the cartridge.

Abstract: A method transfers facial expressions from a performance input to a 3D CG character. The method comprises: providing an inference engine trained for receiving, as input, images exhibiting facial expressions and outputting, for each input image, a 3D CG representation of a CG character having a character facial expression corresponding to that of the input image; receiving performance input, the performance input comprising, or convertible to, one or more performance input images, each of the one or more performance input images exhibiting a performance facial expression; and inputting the performance input images to the inference engine to thereby infer, for each of performance input image, a corresponding 3D CG representation of an output CG character having an inferred character facial expression corresponding to the performance facial expression of the performance input image.