Abstract: Photobiomedulation therapy (PBMT) can be applied to the eye to treat optical neuritis, a sign of multiple sclerosis (MS). The light of PBMT can be directed into the eye, regardless of the position of the eye, by a device that includes an array of light delivery devices and a heat sink lens. The device can be placed proximal to the eye to direct the light into the eye. The light can have one or more wavelengths from 400-1100 nm and can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the skeletal muscle. The light signal is applied for a time sufficient to stimulate a phototherapeutic response in the retina and/or the optic nerve. PBMT applied in this manner provides a noninvasive, safe and effective treatment for optic neuritis.

Abstract: A secure handrail may include an angled mounting bracket that is sized and shaped to fit onto a door. The angled mounting bracket may have a first plate that is sized and shape to fit against an inner face of door jamb when a door is closed in the door jamb. The angle mounting bracket further have a second plate that is sized and shaped to fit against a front face of the door jamb or against a casing mounted over a door jamb, and a handrail connected to the mounting bracket.

Abstract: Photobiomodulation therapy (PBMT) can be used to improve functional mobility of stroke survivors. A light source device can be contacted to a subject's skin proximal to an area of hemiplegia within a subject due to the stroke. A light signal (with wavelengths from the red to infrared part of the spectrum) can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the area of hemiplegia. The light signal is applied for a time sufficient to stimulate a phototherapeutic response in the area of hemiplegia to improve the functional mobility of the subject.

Abstract: Photobiomodulation therapy (PBMT) provides an effective, non-invasive treatment for urinary incontinence that can be used discretely. A light source device can be contacted to a subject's skin proximal to a subject's bladder. A light signal can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the subject's skin proximal to the subject's bladder. The light signal can be applied for a time sufficient to stimulate a phototherapeutic response in one or more muscles and/or nerves proximal to the bladder to treat urinary incontinence.

Abstract: A flexible pail having a container that is adapted to stand upright. The container may have a flexible sheet, a cover, a base, a flap and an odor barrier. The cover may be attached to a first upper end of the flexible sheet, while the base may be attached to a second lower end of the flexible sheet. The cover may have a flap pivotably attached thereto, such that the flap is adapted to pivot between an open position and a closed position. The cover may further have an opening and an odor barrier disposed in the opening.

Abstract: Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.

Abstract: Photobiomedulation therapy (PBMT) can be applied to the eye to treat optical neuritis, a sign of multiple sclerosis (MS). The light of PBMT can be directed into the eye, regardless of the position of the eye, by a device that includes an array of light delivery devices and a heat sink lens. The device can be placed proximal to the eye to direct the light into the eye. The light can have one or more wavelengths from 400-1100 nm and can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the skeletal muscle. The light signal is applied for a time sufficient to stimulate a phototherapeutic response in the retina and/or the optic nerve. PBMT applied in this manner provides a noninvasive, safe and effective treatment for optic neuritis.

Abstract: A gas turbine engine includes: a compressor, a combustor, and a turbine arranged in sequential flow relationship along a primary flowpath, the turbine being connected in mechanical driving relationship to the compressor, so as to define at least one engine rotor that is rotatable about a centerline axis of the engine; a secondary flowpath connected in flow communication with the primary flowpath; and an air cycle machine including an air cycle rotor carrying an at least one air cycle compressor and at least one air cycle expander, wherein: the air cycle rotor is coupled in mechanical driving relationship with the at least one engine rotor; the air cycle rotor is coupled in fluid flow communication with the secondary flowpath; and the air cycle rotor is coupled in fluid flow communication with at least one heat exchanger.

Abstract: A cassette for use in dispensing a pleated tubing. The cassette includes an annular body having an annular channel housing with a central cylindrical core. At least one wall has an upper end with a downturn lip disposed thereon. An annular cover extends radially outward from the central cylindrical core over the annular body defining a gap. The cover has a socket into which the upper end with the downturn lip is secured. A tubing is disposed within the annular channel housing and withdrawn from the gap.

Abstract: A multi-stage lid ultraviolet sterilizing waste container is disclosed which contains a housing, base, lid assembly, support structure for receiving flexible bag assemblies and at least one UV light source for sterilizing the inside of the container. The waste container further includes sensors and motors to automate certain steps.

Abstract: A method of sterilizing a waste container with ultraviolet (UV) light is disclosed which includes, inserting an article of waste into the waste container, sealing the container from an external environment to prevent UV light from shining out, activating a UV sanitizing routine stored in a UV light module having at least one UV light source and irradiating an interior surface of the diaper pail with the UV light.

Abstract: An ultraviolet sterilizing waste container is disclosed which contains a housing, base, lid assembly, support structure for receiving flexible bag assemblies and at least one UV light source for sterilizing the inside of the container.

Abstract: Photobiomodulation therapy (PBMT) provides an effective, non-invasive treatment for urinary incontinence that can be used discretely. A light source device can be contacted to a subject's skin proximal to a subject's bladder. A light signal can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the subject's skin proximal to the subject's bladder. The light signal can be applied for a time sufficient to stimulate a phototherapeutic response in one or more muscles and/or nerves proximal to the bladder to treat urinary incontinence.

Abstract: Respiratory function can be preserved in patients requiring mechanical ventilation (MV), such as patients with severe COVID-19, using a photoceutical applied by a photoceutical medical device (including at least one super pulsed laser to provide superpulsed light of a first wavelength, at least two non-coherent light sources to provide light of a second wavelength, and at least two other non-coherent light sources to provide light of a third wavelength) to at least one inspiratory muscle. The photoceutical includes a combination of superpulsed light of the first wavelength, light of the second wavelength, and light of the third wavelength. At least two sites on the body of the patient can be selected and the photoceutical can be delivered: at one of the sites for a first time period; and at another of the sites for a second time period.

Abstract: A gas turbine engine includes: a compressor, a combustor, and a turbine arranged in sequential flow relationship along a primary flowpath, the turbine being connected in mechanical driving relationship to the compressor, so as to define at least one engine rotor that is rotatable about a centerline axis of the engine; a secondary flowpath connected in flow communication with the primary flowpath; and an air cycle machine including an air cycle rotor carrying an at least one air cycle compressor and at least one air cycle expander, wherein: the air cycle rotor is coupled in mechanical driving relationship with the at least one engine rotor; the air cycle rotor is coupled in fluid flow communication with the secondary flowpath; and the air cycle rotor is coupled in fluid flow communication with at least one heat exchanger.

Abstract: The invention relates to novel genetically modified plants and methods or materials, such as polynucleotides, expression cassettes, or vectors for producing the same. Moreover, the invention relates to altering the content of cannabinoids in plants and to medical compositions derived from such plants. In particular embodiments, the present invention relates to cannabis plants having modified expression of tetrahydrocannabinolic acid (THCA) synthase and methods of modifying the amount of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in cannabis by modifying expression of THCA synthase.

Abstract: An annular fluid flow control or metering device comprises: first and second annular plates disposed in an annular flow path, the first annular plate and second annular plates being made of different first and second materials, the first annular plate having a lower first coefficient of thermal expansion than a second coefficient of thermal expansion of the second annular plate, the first annular plate abutting or in contact with the second annular plate, the first annular plate including at least one first metering aperture, and the second annular plate being more thermally responsive than the first annular plate wherein the second annular plate being configured to radially grow and shrink to at least partly obstruct the at least one first metering aperture for metering or controlling a flow of fluid through the at least one first metering aperture.

Abstract: A seal assembly of a rotary includes a radially oriented plate that axially opposes a front and rear support plates of a stator interface. The seal assembly also includes a film-riding shoe coupled with the radially oriented plate. The shoe forms a shoe fluid bearing between the shoe and a rotating component responsive to rotation of the rotating component and pressurization of fluid in the rotary machine upstream of the stator interface. One or more of the stator interface or the film-riding shoe includes one or more ports or pathways through which higher-pressure fluid upstream of the stator housing in the rotary machine flows to form an aft axial fluid bearing between the radially oriented plate and the rear support plate of the stator interface.

Abstract: An expandable container system including a container, an expandable nipple and a one-way valve. The expandable nipple is attached to the first end of the container and the valve is attached to a second end of the container. A counteracting bias force is generated within the container and a first fluid is drawn in through the valve by extending the expandable nipple. When the expandable nipple is released, the expandable nipple is biased back to an unextended state, and an increase in pressure created by the counteracting bias force induces a second fluid to flow out of an outlet in the expandable nipple.

Abstract: Conformance testing of a rebuilt motor includes disposing a motor under test in a motor test stand, coupling a plurality of sensors to the motor under test including a first vibrational sensor to the motor under test; a first temperature sensor to the motor under test; a first rotational speed sensor to the motor under test. A set of test parameters are received comprising parameters for a conformance test, the test parameters including a vibrational sensor parameter, a temperature sensor parameter, and a rotational speed parameter. A motor under test is placed in an on-state and a processing device receives sensor data simultaneously from the sensors, determines that the rotational speed satisfies the rotational speed parameter, and stores time sampled sensor data received from the plurality of sensors relative to a time zero corresponding to a time when the rotational speed satisfies the rotational speed.