Abstract: A client updates a display of a user interface associated with a state-based client-server application in accordance with a client-side cache. The server supplies data for a new state and additional data for one or more subsequent states that possibly follow the new state if appropriate one or more operations are performed. When a client request is generated that indicates an operation that causes the application to transition to the new state, the client updates the display in accordance with the data that corresponds to the new state from the client-side cache, if available from the client-side cache. The new state data is available since the server has previously supplied the new state data.

Abstract: The presently disclosed subject matter provides a formulation for the use of 1-deoxygalactonojirimycin and/or enzyme replacement therapy for the treatment of Fabry disease.

Abstract: A method of securing, by a managing node, communication in a network of member nodes including a first member node. Communication is secured using a (k, n1) secret sharing scheme during a first phase. The managing node announces a phase shift to a subsequent phase relative to the first phase. The managing node secures communication in the network during the subsequent phase using a (k+x, n2) secret sharing scheme. Each of the member nodes is previously in possession of exactly one corresponding unique share for the second key. The first member node is previously in possession of a first unique share for the second key. The managing node deletes the first member node from the subsequent phase by broadcasting the first unique share for the second key.

Abstract: Described are methods of administering therapeutic gases comprising high concentrations of nitric oxide, particularly concentrations above 2,000 ppm. The therapeutic gas may be administered at a certain dosing rate, such as less than 166 micrograms of nitric oxide per second. Also described are methods of administering a therapeutic gas comprising nitric oxide to a patient, wherein a dose of nitric oxide is administered from a portable device that includes a delivery system and a mini-cylinder. Methods of intermittent administration of nitric oxide pulses are also described.

Abstract: The controller that receives at least one sensor signal indicative of a measured profile of a particulate material within a storage tank of an agricultural system. The controller also determines whether a variation between the measured profile and a target profile is greater than a threshold value. The controller outputs a first output signal to a user interface indicative of instructions to inform an operator of a profile variation, outputs a second output signal to an agitator indicative of activation of the agitator, or a combination thereof, in response to determining that the variation between the measured profile and the target profile is greater than the threshold value.

Abstract: Described are methods of administering therapeutic gases comprising high concentrations of nitric oxide, particularly concentrations above 2,000 ppm. The therapeutic gas may be administered at a certain dosing rate, such as less than 166 micrograms of nitric oxide per second. Also described are methods of administering a therapeutic gas comprising nitric oxide to a patient, wherein a dose of nitric oxide is administered from a portable device that includes a delivery system and a mini-cylinder. Methods of intermittent administration of nitric oxide pulses are also described.

Abstract: Response delay associated with a state-based client-server application can be reduced with utilization of an application state server-side cache. A server caches data for a set of one or more possible states of a client-server application that may follow a current state of the application. The server rapidly responds to a client request with data that corresponds to an appropriate new state of the application in accordance with the application state server-side cache. The server determines that the application will transition to the appropriate new state from the current state of the application with the application state server-side cache based, at least in part, on an operation indicated by the client request.

Abstract: The invention comprises an atomic structure kit for enabling students to understand how atoms are made of smaller sub-atomic particles, the architecture of these particles in relation to each other, and the forces acting upon the sub-atomic particles that hold an atom together. The kit comprises a central body representing an atomic nucleus attached to a shaft about which concentric circular or elliptical rings are rotatably attached. A plurality of bodies representing protons and neutrons is magnetically attachable to the atomic nucleus, and a plurality of bodies representing electrons is magnetically attachable to the rotatable rings. The properties and geometry of the magnetic materials mimic the strong localised force relationships between sub-atomic particles, specifically the electron-electron, proton-proton repulsion, the electron-nucleus attraction and the very strong attraction between the nucleons that bind the nucleus.

Abstract: Described are apparatus and methods for low power frequency clock generation and distribution. A device includes a low power generation and distribution circuit configured to generate and distribute a differential 1/N sampling frequency (FS)(FS/N) clock, wherein N is larger or equal to 2, and a differential frequency doubler configured to generate a single-ended multiplied frequency clock from the differential FS/N frequency clock, and convert the single-ended multiplied frequency clock to a differential multiplied frequency clock for use by one or more data processing channels.

Abstract: An agricultural implement wear monitoring system that monitors a first component of an agricultural implement. A sensor detects and emits a signal indicative of a first geometric dimension of the first component and/or a second geometric dimension of the first component relative to a second component. A controller couples to the sensor. The controller monitors the first geometric dimension and/or the second geometric dimension, and in response to a detected change in the first geometric dimension and/or the second geometric dimension determines a remaining service life of the first component.

Abstract: Methods for identifying premature infants at risk for developing bronchopulmonary dysplasia and/or most likely to benefit from administration of inhaled nitric oxide for prevention of bronchopulmonary dysplasia (BPD). Methods for treating premature infants identified as at risk and/or likely to benefit are provided. also provided are methods for identifying premature infants that are not at risk for developing bronchopulmonary dysplasia and/or unlikely to benefit from administration of inhaled nitric oxide for prevention of bronchopulmonary dysplasia, and methods for avoiding risks of toxicity and undesirable side effects associated with inhaled nitric oxide therapy comprising administering only non-iNO treatment modalities to these infants.

Abstract: A row unit closing wheel assembly includes a closing wheel, a closing wheel arm, and a closing wheel shaft having a first end and a second end. The closing wheel is coupled to the first end and the closing wheel arm is coupled to the second end via a pivot joint. The row unit closing wheel assembly also includes an adjustable wedge assembly including a wedge coupled to the pivot joint. The adjustable wedge assembly is configured to adjust an angle of the closing wheel shaft relative to the closing wheel arm along a horizontal plane via movement of the closing wheel shaft about the pivot joint. The horizontal plane is orthogonal to a rotational axis of the pivot joint.

Abstract: A row unit closing wheel assembly includes a closing wheel, a closing wheel arm, and a closing wheel shaft having a first end and a second end. The closing wheel is coupled to the first end and the closing wheel arm is coupled to the second end via a pivot joint. The row unit closing wheel assembly includes an adjustable mechanical linkage assembly coupled both to the closing wheel shaft and to the closing wheel arm. The adjustable mechanical linkage is configured to adjust an angle of the closing wheel shaft relative to the closing wheel arm along a horizontal plane via movement of the closing wheel shaft about the pivot joint. The horizontal plane is orthogonal to a rotational axis of the pivot joint.

Abstract: A row unit closing wheel assembly includes a closing wheel, a closing wheel arm, and a closing wheel shaft having a first end and a second end. The closing wheel is coupled to the first end and the closing wheel arm is coupled to the second end via a pivot joint. The row unit closing wheel assembly includes an adjustable mechanical assembly disposed at the pivot joint. The adjustable mechanical assembly is configured to adjust an angle of the closing wheel shaft relative to the closing wheel arm along a horizontal plane via movement of the closing wheel shaft about the pivot joint, the horizontal plane being orthogonal to a rotational axis of the pivot joint. The adjustable mechanical assembly includes interlocking teeth and is configured to utilize the interlocking teeth to adjust the angle.

Abstract: The present disclosure is directed to an agitating system having a sub-hopper configured to receive particulate material, an agitator disposed within the sub-hopper and configured to promote movement of the particulate material through the sub-hopper, and a deflector configured to block a portion of the particulate material from exerting a force onto the agitator as the particulate material flows through the sub-hopper. The deflector is positioned such that the agitator extends beyond a first distal edge and a second distal edge of the deflector along a lateral axis.

Abstract: Described are apparatus and methods to calibrate and align multiple high-speed clock domains. A system includes at least two clock domains, a launch circuit connected to each of the at least two domains, and a calibration circuit. Each clock domain including a resettable device having a local reset retime clock. The launch circuit aligns a reset pulse with the local reset retime clock by using a launch clock from one of the domains, where the reset pulse is incoherent with respect to the domains, adjusts a delay of the launch clock to control a launch time of the reset pulse, and sends the reset pulse based on the delayed launch clock. The calibration circuit samples a local reset retime delayed clock to generate a readback signal. The launch circuit and the calibration circuit iterate through selected delays until safe arrival timing is indicated from each readout.

Abstract: Methods for identifying premature infants at risk for developing bronchopulmonary dysplasia and/or most likely to benefit from administration of inhaled nitric oxide for prevention of bronchopulmonary dysplasia (BPD). Methods for treating premature infants identified as at risk and/or likely to benefit are provided. also provided are methods for identifying premature infants that are not at risk for developing bronchopulmonary dysplasia and/or unlikely to benefit from administration of inhaled nitric oxide for prevention of bronchopulmonary dysplasia, and methods for avoiding risks of toxicity and undesirable side effects associated with inhaled nitric oxide therapy comprising administering only non-iNO treatment modalities to these infants.

Abstract: An agricultural system includes a controller comprising a memory and a processor. The controller is configured to receive a sensor signal, determine a current flow based on the sensor signal, determine whether the current flow exceeds a current threshold for a time threshold, and operate a drive system of the agricultural system in an alternative operation instead of a normal operation in response to determining the current flow exceeds the current threshold for the time threshold.

Abstract: A meter roller for an agricultural metering system includes multiple flutes and corresponding recesses. The flutes and the corresponding recesses are configured to meter flowable particulate material from a storage tank to a material distribution system via rotation of the meter roller. The meter roller also includes multiple air passages formed within a body of the meter roller. Each air passage is fluidly coupled to a central cavity of the meter roller and extends to a base of a respective recess, and the air passage is configured to flow air from the central cavity into the respective recess.