Patents by Inventor Douglas B Marks

Douglas B Marks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOPORE SENSOR FOR ENZYME-MEDIATED PROTEIN TRANSLOCATION
    Publication number: 20220396758
    Abstract: Described herein is a device and method for translocating a protein through a nanopore and monitoring electronic changes caused by different amino acids in the protein. The device comprises a nanopore in a membrane, an amplifier for providing a voltage between the cis side and trans side of the membrane, and an NTP driven unfoldase which processed the protein to be trans-located. The exemplified unfoldase is the ClpX unfoldase from E. coli.
    Type: Application
    Filed: May 16, 2022
    Publication date: December 15, 2022
    Inventors: Jeffrey M. NIVALA, Douglas B. MARKS, Mark A. AKESON
  • NANOPORE SENSOR FOR ENZYME-MEDIATED PROTEIN TRANSLOCATION
    Publication number: 20160032236
    Abstract: Described herein is a device and method for translocating a protein through a nanopore and monitoring electronic changes caused by different amino acids in the protein. The device comprises a nanopore in a membrane, an amplifier for providing a voltage between the cis side and trans side of the membrane, and an NTP driven unfoldase which processed the protein to be translocated. The exemplified unfoldase is the ClpX unfoldase from E. coli.
    Type: Application
    Filed: February 15, 2013
    Publication date: February 4, 2016
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jeffrey M Nivala, Douglas B Marks, Mark A Akeson