Abstract: The present invention relates to a composite hydrogel comprising a blend of an aqueous solution of an anionic polysaccharide or a derivative thereof, such as hyaluronan (also commonly referred to as hyaluronic acid) or a derivative thereof and an aqueous solution of methylcellulose or another water soluble cellulose derivative thereof, having dispersed polymeric particles, such as polymeric hydrophobic particles therein selected from micro particles and nanoparticles, and wherein the stability of the hydrogel is enhanced relative to the stability of the hydrogel alone. The polymeric particles may contain at least one therapeutic agent, in which case each therapeutic agent exhibits a linear sustained release rate that can be tuned or altered by selecting the appropriate polymer formulation of the micro particles and/or nanoparticles.

Abstract: The present invention relates to a composite hydrogel comprising a blend of an aqueous solution of an anionic polysaccharide or a derivative thereof, such as hyaluronan (also commonly referred to as hyaluronic acid) or a derivative thereof and an aqueous solution of methylcellulose or another water soluble cellulose derivative thereof, having dispersed polymeric particles, such as polymeric hydrophobic particles therein selected from micro particles and nanoparticles, and wherein the stability of the hydrogel is enhanced relative to the stability of the hydrogel alone. The polymeric particles may contain at least one therapeutic agent, in which case each therapeutic agent exhibits a linear sustained release rate that can be tuned or altered by selecting the appropriate polymer formulation of the micro particles and/or nanoparticles.

Abstract: Novel phosphonium and imidazolium salts and methods for preparing them are disclosed. The novel phosphonium and imidazolium compounds are useful as polar solvents and have the general formula (I): Q+X? wherein Q+ is formula (a) or formula (b); and X? is formula (c), formula (d) or formula (e); and wherein: each of R1, R2, R3, R4, R5, R9, R10, R11, R12, and R13 is independently a hydrocarbyl group; each of R6, R7, and R8 is independently a hydrogen or hydrocarbyl group.

Abstract: Novel phosphonium and imidazolium salts and methods for preparing them are disclosed. The novel phosphonium and imidazolium compounds are useful as polar solvents and have the general formula (I): Q+X? wherein Q+ is formula (a) or formula (b); and X? is formula (c), formula (d) or formula (e); and wherein: each of R1, R2, R3, R4, R5, R9, R10, R11, R12, and R13 is independently a hydrocarbyl group; each of R6, R7, and R8 is independently a hydrogen or hydrocarbyl group.

Abstract: A method is described for creating an inductor in the package for an integrated circuit. The inductor is formed by utilizing one or more of the bond leads as the core of the inductor and by winding a series of coils about the core in connection either with the bond pads of the integrated circuit itself or to other bond leads for connection outside the integrated circuit chip.

Abstract: A metastableproof flip-flop receives an input value on a flip-flop input. The flip-flop holds an output value on a flip-flop output. In response to a transition of a clock signal, a transition in the output value occurs. The new output value is the input value formerly received by the flip-flop. In order to make the flip-flop metastableproof, the transition in the output value is delayed when the input value is in a metastable state. When the input value is no longer in the metastable state, then the transition in the output value is allowed to complete.