Patents by Inventor Douglas Bost

Douglas Bost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF SELECTIVE NUCLEIC ACID ISOLATION
    Publication number: 20150086988
    Abstract: The invention relates to methods for isolating and/or identifying nucleic acids. The invention also provides kits for isolating and/or identifying nucleic acids.
    Type: Application
    Filed: October 2, 2014
    Publication date: March 26, 2015
    Inventors: Douglas BOST, Lawrence GREENFIELD
  • Compositions and methods of selective nucleic acid isolation
    Patent number: 8865405
    Abstract: The invention relates to methods for isolating and/or identifying nucleic acids. The invention also provides kits for isolating and/or identifying nucleic acids.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: October 21, 2014
    Assignee: Applied BioSystems LLC
    Inventors: Douglas Bost, Lawrence Greenfield
  • Compositions and methods of selective nucleic acid isolation
    Publication number: 20070224630
    Abstract: The invention relates to methods for isolating and/or identifying nucleic acids. The invention also provides kits for isolating and/or identifying nucleic acids.
    Type: Application
    Filed: April 23, 2007
    Publication date: September 27, 2007
    Inventors: Douglas Bost, Lawrence Greenfield
  • Integrated method for PCR cleanup and oligonucleotide removal
    Publication number: 20060141523
    Abstract: A method is provided for purifying a desired polynucleotide product by removing unincorporated oligonucleotides from a polymerase or ligase reaction mixture.
    Type: Application
    Filed: February 17, 2006
    Publication date: June 29, 2006
    Applicant: Applera Corporation
    Inventors: Lawrence Greenfield, Douglas Bost
  • Multiplex protease profiling
    Publication number: 20050176076
    Abstract: In certain embodiments, provided are methods and compositions useful for the detection and quantitation of catalytically active enzymes, particularly catalytically active proteases. The compositions comprise one or more multifunctional tags, wherein each different multifunctional tag comprises a different mobility modifier, a partitioner, a reporter, and a peptide substrate that is specifically or substantially specifically hydrolyzed by a target protease or target protease family. Hydrolysis of each different multifunctional tag by a target protease provides a different labeled hydrolytic product comprising a reporter and a mobility modifier but not a partitioner, where the mobility modifier confers a distinctive mobility on the labeled hydrolytic product in a mobility-dependent analysis technique.
    Type: Application
    Filed: December 28, 2004
    Publication date: August 11, 2005
    Inventors: Hongye Sun, Lawrence Greenfield, Douglas Bost