Patents by Inventor Douglas Bruce Kell

Douglas Bruce Kell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230167469
    Abstract: The present invention relates to KatG enzymes and enzyme compositions and their uses in enzymatic degradation of plastics.
    Type: Application
    Filed: April 6, 2021
    Publication date: June 1, 2023
    Inventors: Jacob Leon Nathan, Douglas Bruce Kell
  • Publication number: 20220220520
    Abstract: The present invention relates to microbial factories, in particular yeast factories, for production of ergothioneine. Also provided are methods for producing ergothioneine in a yeast cell, as well as useful nucleic acids, polypeptides, vectors and host cells.
    Type: Application
    Filed: April 29, 2020
    Publication date: July 14, 2022
    Inventors: Irina BORODINA, Douglas Bruce KELL, Steven van der HOEK, Behrooz Darbani SHIRVANEHDEH
  • Patent number: 11357822
    Abstract: A method for treating a subject suffering from Alzheimer's disease is provided. The method includes administering to the subject a therapeutically effective amount of lipopolysaccharide-binding protein (LBP). A composition including a therapeutically effective amount of LBP is also provided.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: June 14, 2022
    Assignee: Stellenbosch University
    Inventors: Etheresia Pretorius, Douglas Bruce Kell
  • Publication number: 20220145340
    Abstract: Integral membrane proteins capable of transporting melatonin and other indole-derivatives across biological membranes, and uses thereof.
    Type: Application
    Filed: March 13, 2020
    Publication date: May 12, 2022
    Inventors: Douglas Bruce Kell, Lei Yang, Sailesh Malla
  • Publication number: 20210187068
    Abstract: A method for treating a subject suffering from Alzheimer's disease is provided. The method includes administering to the subject a therapeutically effective amount of lipopolysaccharide-binding protein (LBP). A composition including a therapeutically effective amount of LBP is also provided.
    Type: Application
    Filed: October 4, 2017
    Publication date: June 24, 2021
    Inventors: Etheresia Pretorius, Douglas Bruce Kell
  • Publication number: 20200363403
    Abstract: A method of detecting inflammation in a subject is provided. The method comprises determining a quantity of amyloid present in fibrin(ogen) protein in a blood sample obtained from the subject, and assigning a level of inflammation in the subject based on the quantity of fibrin(ogen) amyloid determined. A method of determining an effect of a therapeutic treatment on a subject by comparing a pre-treatment level of inflammation with a post-treatment level is further provided.
    Type: Application
    Filed: November 13, 2018
    Publication date: November 19, 2020
    Inventors: Etheresia PRETORIUS, Douglas Bruce KELL, Willem Johan Simon DE VILLIERS
  • Patent number: 6496020
    Abstract: A method for analyzing a dielectric medium comprises the step of measuring, at one or more frequencies, the capacitance between a pair of electrodes immersed in the dielectric medium. The proportion of the or each capacitance measurement due to electrode polarization capacitance and/or to the residual capacitance of the dielectric medium is then determined using capacitance measurements made between the electrodes at a first frequency and at a second frequency, the ratio of the respective polarization capacitances at these two frequencies being predetermined. An apparatus for performing the method is also disclosed.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: December 17, 2002
    Assignee: University of Wales Aberystwyth
    Inventors: Christopher Lyndon Davey, Douglas Bruce Kell
  • Patent number: 5946640
    Abstract: A method and apparatus for analysing a sample, in which a neural network is trained to correct for measurement drift of a given analytical instrument (e.g., a mass spectrometer). The training is carried out using first and second sets of data obtained by the instrument from samples of known compositions at initial and subsequent instants of time, respectively. The trained neural network is used to transform data, obtained by the instrument from a sample of unknown composition at said subsequent instant of time, to an estimate of the data which would have been obtained by the instrument from that sample at the initial instant of time. The transformed dasta is then analysed to analyse the sample of unknown composition.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: August 31, 1999
    Assignee: University of Wales Aberystwyth
    Inventors: Royston Goodacre, Douglas Bruce Kell