Patents by Inventor Douglas Cyr

Douglas Cyr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for treatment of cystic fibrosis
    Patent number: 10130622
    Abstract: A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of cystic fibrosis.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: November 20, 2018
    Assignees: AbbVie S.á.r.l., Galapagos NV
    Inventors: Rhalid Akkari, Luke Jonathan Alvey, Xavier Marie Bock, Brian S. Brown, Pieter Isabelle Roger Claes, Marlon D. Cowart, Katja E. Conrath, Douglas Cyr, Elsa De Lemos, Gert Jules Hector De Wilde, Nicolas Desroy, Béranger Duthion, Gregory A. Gfesser, Romain Luc Marie Gosmini, Christopher Gaëtan Housseman, Koen Karel Jansen, Jianguo Ji, Philip R. Kym, Jean-Michel Lefrancois, Oscar Mammoliti, Christel Jeanne Marie Menet, Nuria Merayo Merayo, Gregory John Robert Newsome, Adeline Marie Elise Palisse, Sachin V. Patel, Mathieu Rafaël Pizzonero, Anurupa Shrestha, Elizabeth C. Swift, Chris Tse, Steven Emiel Van der Plas, Xueqing Wang
  • NOVEL COMPOUNDS FOR TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20170100386
    Abstract: A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of cystic fibrosis.
    Type: Application
    Filed: October 7, 2016
    Publication date: April 13, 2017
    Inventors: Rhalid Akkari, Luke Jonathan Alvey, Xavier Marie Bock, Brian S. Brown, Pieter Isabelle Roger Claes, Marlon D. Cowart, Katja E. Conrath, Douglas Cyr, Elsa De Lemos, Gert Jules Hector De Wilde, Nicolas Desroy, Béranger Duthion, Gregory A. Gfesser, Romain Luc Marie Gosmini, Christopher Gaëtan Housseman, Koen Karel Jansen, Jianguo Ji, Philip R. Kym, Jean-Michel Lefrancois, Oscar Mammoliti, Christel Jeanne Marie Menet, Nuria Merayo Merayo, Gregory John Robert Newsome, Adeline Marie Elise Palisse, Sachin V. Patel, Mathieu Rafaël Pizzonero, Anurupa Shrestha, Elizabeth C. Swift, Chris Tse, Steven Emiel Van der Plas, Xueqing Wang
  • CORRECTORS ACTING THROUGH MSD1 OF CFTR PROTEIN
    Publication number: 20160074374
    Abstract: The present disclosure provides methods for treating Cystic Fibrosis in a subject by administering to the subject a corrector agent capable of acting through MSD1 during the biosynthesis of CFTR protein. The disclosure also provides methods of screening for new corrector agents capable of acting through MSD1 during the biosynthesis of a CFTR protein.
    Type: Application
    Filed: April 25, 2014
    Publication date: March 17, 2016
    Inventors: Fredrick F. Van Goor, Beth Jennifer Hoffman, Oxana Adolfovna de la Rosa, Douglas Cyr
  • CORRECTORS ACTING THROUGH MSD1 OF CFTR PROTEIN
    Publication number: 20160030406
    Abstract: The present disclosure provides methods for treating Cystic Fibrosis in a subject by administering to the subject a corrector agent capable of acting through MSD1 during the biosynthesis of CFTR protein. The disclosure also provides methods of screening for new corrector agents capable of acting through MSD1 during the biosynthesis of a CFTR protein.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Fredrick F. Van Goor, Beth Jennifer Hoffman, Oxana Adolfovna de la Rosa, Douglas Cyr
  • Composite Polymer Microfluidic Control Device
    Publication number: 20080038674
    Abstract: A device for microfluidic control comprising a regulator that is moveable in a conduit where the regulator is a composite polymer formed from a composite mixture comprising a polymerizable precursor and a particulate filler.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 14, 2008
    Inventors: Jason Rehm, Phillip Paul, Douglas Cyr
  • Composite Polymer Microfludic Control Device
    Publication number: 20070272309
    Abstract: A device for microfluidic control comprising a regulator that is moveable in a conduit where the regulator is a composite polymer formed from a composite mixture comprising a polymerizable precursor and a particulate filler.
    Type: Application
    Filed: September 15, 2004
    Publication date: November 29, 2007
    Inventors: Jason Rehm, Phillip Paul, Douglas Cyr, Sammy Datwani, Klaus Dahl
  • MICROFLUIDIC DETECTION DEVICE HAVING REDUCED DISPERSION AND METHOD FOR MAKING SAME
    Publication number: 20070104408
    Abstract: A microfluidic detection device provides reduced dispersion of axial concentration gradients in a flowing sample. The microfluidic detection device includes a cell body and a flow path through the cell body. The flow path has an inlet segment, an outlet segment, and a central segment, which forms a detection cell. The central segment is located between and at an angle with both the inlet segment and the outlet segment. The central segment has a first junction with the inlet segment and a second junction with the outlet segment. The cell body contains two arms that can transmit light to and from the detection cell. At least a portion of a first arm is located in the first junction and at least a portion of a second arm is located in the second junction. The portions of the arms located in the junctions are situated so that fluid entering or exiting the central segment of the flow path flows around the outer surface of one of the portions.
    Type: Application
    Filed: April 19, 2006
    Publication date: May 10, 2007
    Inventors: Douglas Cyr, Roger Farrow, Don Arnold
  • Composite polymer microfluidic control device
    Publication number: 20050056321
    Abstract: A device for microfluidic control comprising a regulator that is moveable in a conduit where the regulator is a composite polymer formed from a composite mixture comprising a polymerizable precursor and a particulate filler.
    Type: Application
    Filed: September 16, 2003
    Publication date: March 17, 2005
    Inventors: Jason Rehm, Phillip Paul, Douglas Cyr