Patents by Inventor Douglas Dority
Douglas Dority has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240068030Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having a well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.Type: ApplicationFiled: October 4, 2023Publication date: February 29, 2024Inventors: Yuh-Min Chiang, Douglas Dority, Dustin Dickens, Jennifer Glass, Reuel Van Atta
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Patent number: 11795506Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.Type: GrantFiled: November 24, 2020Date of Patent: October 24, 2023Assignee: CepheidInventors: Yuh-Min Chiang, Douglas Dority, Dustin Dickens, Jennifer Glass, Reuel Van Atta
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Publication number: 20210147933Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.Type: ApplicationFiled: November 24, 2020Publication date: May 20, 2021Inventors: Yuh-Min Chiang, Douglas Dority, Dustin Dickens, Jennifer Glass, Reuel Van Atta
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Patent number: 9316590Abstract: The present invention provides a reaction vessel and apparatus for performing heat-exchanging reactions. The vessel has a chamber for holding a sample, the chamber being defined by a plurality of walls, at least two of the walls being light transmissive to provide optical windows to the chamber. The apparatus comprises at least one heating surface for contacting at least one of the plurality of walls, at least one heat source for heating the surface, and optics positioned to optically interrogate the chamber while the heating surface is in contact with at least one of the plurality of walls.Type: GrantFiled: October 1, 2012Date of Patent: April 19, 2016Assignee: CepheidInventors: Ronald Chang, Douglas Dority
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Patent number: 9212980Abstract: A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers.Type: GrantFiled: January 31, 2014Date of Patent: December 15, 2015Assignee: CepheidInventors: Douglas Dority, Ronald Chang
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Publication number: 20140295479Abstract: A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers.Type: ApplicationFiled: January 31, 2014Publication date: October 2, 2014Applicant: CepheidInventors: Douglas DORITY, Ronald CHANG
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Patent number: 8728765Abstract: The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers.Type: GrantFiled: February 15, 2012Date of Patent: May 20, 2014Assignee: CepheidInventors: Jesus Ching, Ronald Chang, Douglas Dority, Jian Ping Zhang, James Jian Quan Wang, Wendy Wong, Kendra Lara Paul, Reuel Van Atta
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Patent number: 8709363Abstract: A cartridge for conducting a chemical reaction includes a body having at least one flow path formed therein. The cartridge also includes a reaction vessel extending from the body for holding a reaction mixture for chemical reaction and optical detection. The vessel comprises a rigid frame defining the side walls of a reaction chamber. The frame includes at least one channel connecting the flow path to the chamber. The vessel also includes flexible films or sheets attached to opposite sides of the rigid frame to form opposing major walls of the chamber. In addition, at least two of the side walls are optically transmissive and angularly offset from each to permit real-time optical detection of analyte in the reaction chamber.Type: GrantFiled: March 30, 2012Date of Patent: April 29, 2014Assignee: CepheidInventors: Kurt Petersen, William McMillan, Farzad Pourahmadi, Ronald Chang, Douglas Dority
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Patent number: 8673238Abstract: A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers.Type: GrantFiled: April 1, 2013Date of Patent: March 18, 2014Assignee: CepheidInventors: Douglas Dority, Ronald Chang
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Publication number: 20140004621Abstract: A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers.Type: ApplicationFiled: April 1, 2013Publication date: January 2, 2014Applicant: CepheidInventors: DOUGLAS DORITY, Ronald Chang
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Publication number: 20120244534Abstract: The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers.Type: ApplicationFiled: February 15, 2012Publication date: September 27, 2012Applicant: CephiedInventors: Jesus Ching, Ronald Chang, Douglas Dority, Jian Ping Zhang, James Jian Quan Wang, Wendy Wingkei Wong, Kendra Lara Paul, Reuel Van Atta
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Publication number: 20080057572Abstract: The present invention provides a cartridge for analyzing a fluid sample. The cartridge provides for the efficient separation of cells or viruses in the sample from the remaining sample fluid, lysis of the cells or viruses to release the analyte (e.g., nucleic acid) therefrom, and optionally chemical reaction and/or detection of the analyte. The cartridge is useful in a variety of diagnostic, life science research, environmental, or forensic applications for determining the presence or absence of one or more analytes in a sample.Type: ApplicationFiled: October 24, 2007Publication date: March 6, 2008Applicant: CepheidInventors: Kurt Petersen, Michael Taylor, Farzad Pourahmadi, William McMillan, Ronald Chang, Stanley Sakai, Jesus Ching, Douglas Dority, Phillip Belgrader, M. Northrup
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Publication number: 20060275178Abstract: Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In one embodiment, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge.Type: ApplicationFiled: June 6, 2005Publication date: December 7, 2006Applicant: CEPHEIDInventors: Ronald Chang, Douglas Dority, Steven Montgomery
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Publication number: 20060177844Abstract: The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers.Type: ApplicationFiled: October 27, 2005Publication date: August 10, 2006Applicant: CepheidInventors: Jesus Ching, Ronald Chang, Douglas Dority, Jian Ping Zhang, James Wang, Wendy Wong, Kendra Paul, Reuel Van Atta
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Publication number: 20050042137Abstract: A cartridge for conducting a chemical reaction includes a body having at least one flow path formed therein. The cartridge also includes a reaction vessel extending from the body for holding a reaction mixture for chemical reaction and optical detection. The vessel comprises a rigid frame defining the side walls of a reaction chamber. The frame includes at least one channel connecting the flow path to the chamber. The vessel also includes flexible films or sheets attached to opposite sides of the rigid frame to form opposing major walls of the chamber. In addition, at least two of the side walls are optically transmissive and angularly offset from each to permit real-time optical detection of analyte in the reaction chamber.Type: ApplicationFiled: September 29, 2004Publication date: February 24, 2005Applicant: CEPHEIDInventors: Kurt Petersen, William McMillan, Farzad Pourahmadi, Ronald Chang, Douglas Dority