Patents by Inventor Douglas E. Bell

Douglas E. Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8529741
    Abstract: Methods and devices for determining the concentration of a constituent in a physiological sample are provided. The blood sample is introduced into a test strip with portions of the blood sample being directed to both a first capillary and a second capillary. The first capillary configured to electrochemically determine a concentration of a first analyte in a blood sample by measuring a signal across a set of electrodes. The second capillary is configured to determine a hematocrit value of the blood sample by measuring a signal across a second set of electrodes.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: September 10, 2013
    Assignee: Nipro Diagnostics, Inc.
    Inventors: Gary T. Neel, Douglas E. Bell, Dennis Slomski, David Z. Deng
  • Publication number: 20120241318
    Abstract: Methods and devices for determining the concentration of a constituent in a physiological sample are provided. The blood sample is introduced into a test strip with portions of the blood sample being directed to both a first capillary and a second capillary. The first capillary configured to electrochemically determine a concentration of a first analyte in a blood sample by measuring a signal across a set of electrodes. The second capillary is configured to determine a hematocrit value of the blood sample by measuring a signal across a second set of electrodes.
    Type: Application
    Filed: February 23, 2012
    Publication date: September 27, 2012
    Inventors: Gary T. Neel, Douglas E. Bell, Dennis Slomski, David Z. Deng
  • Patent number: 8062490
    Abstract: Biological reagent compositions with improved sensitivity to the concentration of blood glucose in patient samples for use in measuring systems and methods. The reagent compositions comprise a glucose oxidoreductase enzyme, a flavin nucleoside coenzyme and a mediator formulation. The mediator formulation comprises at least one electroactive organic molecule and at least one coordination complex.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: November 22, 2011
    Assignee: Nipro Diagnostics, Inc.
    Inventors: Douglas E. Bell, Michele Albino
  • Patent number: 7819161
    Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: October 26, 2010
    Assignee: Nipro Diagnostics, Inc.
    Inventors: Gary T. Neel, Douglas E. Bell, T. Philip Wong, Houston F. Voss, Allan Javier Caban, David K. Boehm
  • Publication number: 20100227355
    Abstract: Biological reagent compositions with improved sensitivity to the concentration of blood glucose in patient samples for use in measuring systems and methods. The reagent compositions comprise a glucose oxidoreductase enzyme, a flavin nucleoside coenzyme and a mediator formulation. The mediator formulation comprises at least one electroactive organic molecule and at least one coordination complex.
    Type: Application
    Filed: March 15, 2010
    Publication date: September 9, 2010
    Applicant: Home Diagnostics, Inc.
    Inventors: Douglas E. Bell, Michele Albino
  • Patent number: 7678250
    Abstract: Biological reagent compositions with improved sensitivity to the concentration of blood glucose in patient samples for use in measuring systems and methods. The reagent compositions comprise a glucose oxidoreductase enzyme, a flavin nucleoside coenzyme and a mediator formulation. The mediator formulation comprises at least one electroactive organic molecule and at least one coordination complex.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: March 16, 2010
    Assignee: Home Diagnostics, Inc.
    Inventors: Douglas E. Bell, Michele Albino
  • Publication number: 20090186372
    Abstract: Biological reagent compositions with improved sensitivity to the concentration of blood glucose in patient samples for use in measuring systems and methods. The reagent compositions comprise a glucose oxidoreductase enzyme, a flavin nucleoside coenzyme and a mediator formulation. The mediator formulation comprises at least one electroactive organic molecule and at least one coordination complex.
    Type: Application
    Filed: January 22, 2008
    Publication date: July 23, 2009
    Inventors: Douglas E. Bell, Michele Albino
  • Patent number: 7560288
    Abstract: An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test strip includes fluid volume control dams to prevent spillage of the fluid from the strip and a chemical reagent solution that facilitates end-point testing.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: July 14, 2009
    Assignee: Home Diagnostics, Inc.
    Inventors: Patrick Carroll, Jon Schneider, Douglas E. Bell
  • Publication number: 20090170188
    Abstract: An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test strip includes fluid volume control dams to prevent spillage of the fluid from the strip and a chemical reagent solution that facilitates end-point testing.
    Type: Application
    Filed: March 5, 2009
    Publication date: July 2, 2009
    Inventors: Patrick Carroll, Jon Schneider, Douglas E. Bell
  • Publication number: 20080149480
    Abstract: Devices for determining the concentration of a constituent in a physiological sample that comprise gel matrices to filter red blood cells are provided. Examples of such devices include a biosensor comprising, on a support substrate, a sample reception region for receiving a blood sample; at least one electrode; and a reaction reagent system that is located in a gel matrix. The gel matrix disclosed herein is sufficient to prevent at least some of the red cells in the blood sample from contacting the electrode, and thus reduce the hematocrit sensitivity in the measurement.
    Type: Application
    Filed: December 17, 2007
    Publication date: June 26, 2008
    Inventor: Douglas E. Bell
  • Publication number: 20080112852
    Abstract: A test strip for measuring an analyte level in a fluid sample includes a sample chamber configured to receive the fluid sample; a plurality of electrodes configured to produce at least one current measurement related to the analyte level in the fluid sample; and at least one information-providing connector having an intrinsic electrical property representative of at least one test strip calibration parameter specific to the test strip. A system for measuring an analyte level in a fluid sample may include such a test strip along with a data acquisition system controlled by a processor and configured to measure an intrinsic electrical property of the information-providing connector and to obtain at least one test strip calibration parameter corresponding to the test strip from at least one predetermined location in a memory based on the intrinsic electrical property.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 15, 2008
    Inventors: Gary T. Neel, Douglas E. Bell
  • Patent number: 7160251
    Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: January 9, 2007
    Assignee: Home Diagnostics, Inc.
    Inventors: Gary T. Neel, Douglas E. Bell, T. Philip Wong
  • Patent number: 7049130
    Abstract: An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test strip includes fluid volume control dams to prevent spillage of the fluid from the strip and a chemical reagent solution that facilitates end-point testing.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: May 23, 2006
    Assignee: Home Diagnostics, Inc.
    Inventors: Patrick Carroll, Jon Schneider, Douglas E. Bell
  • Patent number: 6991940
    Abstract: An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the analyte in the fluid, wherein the test strip includes fluid volume control dams to prevent spillage of the fluid from the strip and a chemical reagent solution that facilitates end-point testing.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: January 31, 2006
    Assignee: Home Diagnostics, Inc.
    Inventors: Patrick Carroll, Jon Schneider, Douglas E. Bell
  • Patent number: 6964871
    Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber or other testing zone, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the testing zone. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: November 15, 2005
    Assignee: Home Diagnostics, Inc.
    Inventors: Douglas E. Bell, Gary T. Neel, T. Philip Wong
  • Patent number: 6959247
    Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: October 25, 2005
    Assignee: Home Diagnostics, Inc.
    Inventors: Gary T. Neel, Douglas E. Bell, T. Philip Wong, Allan Javier Caban, David K. Boehm
  • Patent number: 6953693
    Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: October 11, 2005
    Assignee: Home Diagnostics, Inc.
    Inventors: Gary T. Neel, Douglas E. Bell, T. Philip Wong
  • Patent number: 6946299
    Abstract: A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
    Type: Grant
    Filed: April 21, 2003
    Date of Patent: September 20, 2005
    Assignee: Home Diagnostics, Inc.
    Inventors: Gary T. Neel, Douglas E. Bell, T. Philip Wong, Houston F. Voss, Allan Javier Caban, David K. Boehm
  • Patent number: 6835351
    Abstract: An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a luminescence indicator (I) and a polymer (H) carrying the luminescence indicator (I) is characterized in that the luminescence indicator (I) is a non-lipophile acridine or bisacridine compound and the polymer (H) is a linear-chain hydrophile polymer soluble in an organic solvent, whereby it is possible to excite the sensor by commercially available LEDs, to manufacture very large numbers thereof at a moderate cost and in a reproducible way and, preferably, to use it for the determination of physiological chloride concentrations and the sensor furthermore has a wide dynamic measuring range for the determination of chloride; a high sensitivity, stability and reproducibility; a high selectivity for chloride; and a low pH cross-sensitivity.
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: December 28, 2004
    Assignee: F. Hoffmann-La Roche AG
    Inventors: Christian Huber, Tobias Werner, Otto S. Wolfbeis, Douglas E. Bell, Susannah Young
  • Patent number: D512512
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: December 6, 2005
    Assignee: Wachovia Bank, National Association
    Inventors: Douglas E. Bell, Gary T. Neel, Houston F. Voss