Patents by Inventor Douglas E. Berg

Douglas E. Berg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Means of controlling infection persistence of
    Patent number: 8992935
    Abstract: The present invention relates to a means of controlling infection persistence of Helicobacter pylori (H. pylori). In particular, the present invention relates to an isolated, genetically modified Helicobacter pylori comprising a functional urease, wherein the contiguous amino acid sequence between amino acid 529 and amino acid 555 of SEQ ID NO:1 is altered to produce said modified Helicobacter pylori which is unable to establish or maintain a persistent infection.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: March 31, 2015
    Assignee: Ondek Pty. Ltd.
    Inventors: Mohammed Benghezal, Tobias Schoep, Alma Fulurija, Douglas E. Berg, Barry J. Marshall
  • MEANS OF CONTROLLING INFECTION PERSISTENCE OF HELICOBACTER PYLORI
    Publication number: 20130259888
    Abstract: The present invention relates to a means of controlling infection persistence of Helicobacter pylori (H. pylori). In particular, the present invention relates to an isolated, genetically modified Helicobacter pylori comprising a functional urease, wherein the contiguous amino acid sequence between amino acid 529 and amino acid 555 of SEQ ID NO:1 is altered to produce said modified Helicobacter pylori which is unable to establish or maintain a persistent infection.
    Type: Application
    Filed: June 24, 2011
    Publication date: October 3, 2013
    Applicant: ONDEK PTY LTD
    Inventors: Mohammed Benghezal, Tobias Schoep, Alma Fulurija, Douglas E. Berg, Barry J. Marshall
  • DNA transposon Tn5seq1
    Patent number: 5869296
    Abstract: A novel transposon useful for sequencing long DNAs is disclosed which comprises a partial sequence of transposon Tn5 with the oligonucleotide primers from phages SP6 and T7 inserted near the opposite ends, respectively, of said transposon Tn5.
    Type: Grant
    Filed: January 14, 1993
    Date of Patent: February 9, 1999
    Assignee: Washington University
    Inventors: Dilip K. Nag, Henry V. Huang, Douglas E. Berg
  • Transposon-containing DNA cloning vector and uses thereof
    Patent number: 5645991
    Abstract: The present invention discloses a rapid method of restriction mapping, sequencing or localizing genetic features in a segment of deoxyribonucleic acid (DNA) that is up to 42 kb in size. The method in part comprises cloning of the DNA segment in a specialized cloning vector and then isolating nested deletions in either direction in vivo by intramolecular transposition into the cloned DNA. A plasmid has been prepared and disclosed.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: July 8, 1997
    Assignees: Univ. of Connecticut, Washington University
    Inventors: Claire M. Berg, Douglas E. Berg, Gan Wang
  • Method of DNA sequencing using DNA transposon Tn5seql
    Patent number: 5212080
    Abstract: A novel transposon useful for sequencing long DNAs is disclosed which comprises a partial sequence of transposon Tn5 with the oligonucleotide primers from phages SP6 and T7 inserted near the opposite ends, respectively, of said transposon Tn5.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: May 18, 1993
    Assignee: Washington University
    Inventors: Dilip K. Nag, Henry V. Huang, Douglas E. Berg
  • DNA transposon TN5SEQ1
    Patent number: 5137829
    Abstract: A novel transposon useful for sequencing long DNAs is disclosed which comprises a partial sequence of transposon Tn5 with the oligonucleotide primers from phages SP6 and T7 inserted near the opposite ends, respectively, of said transposon Tn5.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: August 11, 1992
    Assignee: Washington University
    Inventors: Dilip K. Nag, Henry V. Huang, Douglas E. Berg