Patents by Inventor Douglas E. Berning

Douglas E. Berning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7556863
    Abstract: A process of preparing gold-coated magnetic nanoparticles is disclosed and includes forming a suspension of magnetic nanoparticles within a suitable liquid, adding an amount of a reducible gold compound and a reducing agent to the suspension, and, maintaining the suspension for time sufficient to form gold-coated magnetic nanoparticles.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: July 7, 2009
    Assignee: Los Alamos National Security, LLC
    Inventors: Douglas E. Berning, Robert H. Kraus, Jr., Robert W. Atcher, Jurgen G. Schmidt
  • Publication number: 20080305337
    Abstract: A process of preparing gold-coated magnetic nanoparticles is disclosed and includes forming a suspension of magnetic nanoparticles within a suitable liquid, adding an amount of a reducible gold compound and a reducing agent to the suspension, and, maintaining the suspension for time sufficient to form gold-coated magnetic nanoparticles.
    Type: Application
    Filed: June 5, 2007
    Publication date: December 11, 2008
    Inventors: Douglas E. Berning, Robert H. Kraus, JR., Robert W. Atcher, Jurgen G. Schmidt
  • Patent number: 7226636
    Abstract: A process of preparing gold-coated magnetic nanoparticles is disclosed and includes forming a suspension of magnetic nanoparticles within a suitable liquid, adding an amount of a reducible gold compound and a reducing agent to the suspension, and, maintaining the suspension for time sufficient to form gold-coated magnetic nanoparticles.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: June 5, 2007
    Assignee: Los Alamos National Security, LLC
    Inventors: Douglas E. Berning, Robert H. Kraus, Jr., Robert W. Atcher, Jurgen G. Schmidt
  • Patent number: 6054115
    Abstract: A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises at least one functionalized hydroxyalkyl phosphine donor group and one or more sulfur or nitrogen donor and a metal combined with the ligand.
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: April 25, 2000
    Assignee: The Curators of the University of Missouri
    Inventors: Kattesh V. Katti, Srinivasa Rao Karra, Douglas E. Berning, C. Jeffrey Smith, Wynn A. Volkert, Alan R. Ketring
  • Patent number: 5948386
    Abstract: A method of forming phosphine-amine conjugates includes reacting a hydroxymethyl phosphine group of an amine-free first molecule with at least one free amine group of a second molecule to covalently bond the first molecule with the second molecule through an aminomethyl phosphorus linkage and the conjugates formed thereby.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: September 7, 1999
    Assignee: The Curators of the University of Missouri
    Inventors: Kattesh V. Katti, Douglas E. Berning, Wynn A. Volkert, Alan R. Ketring, Robert Churchill
  • Patent number: 5855867
    Abstract: A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises at least one functionalized hydroxyalkyl phosphine donor group and one or more sulfur or nitrogen donor and a metal combined with the ligand.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: January 5, 1999
    Assignee: The Curators of the University of Missouri
    Inventors: Kattesh V. Katti, Srinivasa Rao Karra, Douglas E. Berning, C. Jeffrey Smith, Wynn A. Volkert, Alan R. Ketring
  • Patent number: 5843993
    Abstract: A complex and method for making same for use as a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: December 1, 1998
    Assignee: The Curators of the University of Missouri
    Inventors: Kattesh V. Katti, Douglas E. Berning, Wynn A. Volkert, Alan R. Ketring