Patents by Inventor Douglas E. Bigler

Douglas E. Bigler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified factor IX preparation
    Publication number: 20040106779
    Abstract: The present invention relates to a modification of the anion exchange chromatography step in a Factor IX purification process. By the modification the presence of the protease, plasma hyaluronan binding protease, is decreased which minimizes the cleavage of Factor IX and enhances the yield of Factor IX in the purification process.
    Type: Application
    Filed: December 3, 2002
    Publication date: June 3, 2004
    Inventors: Douglas E. Bigler, Sourav K. Kundu, Holger Lind, Stefan Schulte