Abstract: Pumping mechanisms for performing peritoneal dialysis and the like employ a pumping mechanism comprising a diaphragm that operate in response to applied fluid pressure. Flexible tubing is attached to the pumping mechanism for carrying liquid to and from the patient's peritoneal cavity. An actuating station for pumping mechanism receives the pumping mechanism and attached tubing. A pressure transfer element conveys fluid pressure to the diaphragm for moving liquid through the cassette. An occluder element contacts and crimps closed the tubing attached to the cassette. A first reservoir inflates with positive fluid pressure for contacting the pressure transfer element to hold it in operative contact against the diaphragm. A second reservoir inflates with positive fluid pressure for contacting the occluding element to hold it away from crimping contact with the tubing. At least one of the first and second reservoirs also transports fluid pressure to the pressure transfer element for conveyance to the diaphragm.

Abstract: Systems and methods for peritoneal dialysis establish flow communication between a patient's peritoneal cavity and a drain through a pump chamber having generally vertically spaced upper and lower regions andt a diaphragm. The systems and methods operate the pump chamber, with the upper and lower regions oriented generally vertically, by applying fluid pressure to the diaphragm. The systems and methods direct liquid to the patient's peritoneal cavity only from the lower region of the pump chamber. In this way, the improved systems and methods collect air in the upper region of the vertically oriented pump chamber, while isolating the patient's peritoneal cavity from air in the pump chamber.

Abstract: A process is provided for ultrasonically welding a rigid thermoplastic, such as acrylic, and a flexible thermoplastic, such a polyvinyl chloride (PVC) doped with plasticizers. The rigid piece includes an energy director where the joint is to be located. The energy director includes first and second ridges running the length of the joint and a groove running between the first and second ridges. The energy director is placed against one side of the flexible piece, and an ultrasonic horn against the other side opposite the energy director. The two pieces are then welded together using standard ultrasonic technology. The shape of the energy director promotes the melting and flow of both pieces as they are being welded together.

Abstract: Peritoneal dialysis systems and methods move liquid using a pump chamber that is operated in response to pneumatic pressure variations applied by a pump actuator. The systems and methods periodically measure air pressures in the actuator and an associated reference air chamber and derive from these a measurement of liquid volume moved through the pump chamber. The systems and methods minimize derivation errors by compensating for temperature differences among the pump chamber; the pump actuator; and the reference chamber.

Abstract: Pumping mechanisms for performing peritoneal dialysis and the like employ a pumping mechanism comprising a diaphragm that operate in response to applied fluid pressure. Flexible tubing is attached to the pumping mechanism for carrying liquid to and from the patient's peritoneal cavity. An actuating station for pumping mechanism receives the pumping mechanism and attached tubing. A pressure transfer element conveys fluid pressure to the diaphragm for moving liquid through the cassette. An occluder element contacts and crimps closed the tubing attached to the cassette. A first reservoir inflates with positive fluid pressure for contacting the pressure transfer element to hold it in operative contact against the diaphragm. A second reservoir inflates with positive fluid pressure for contacting the occluding element to hold it away from crimping contact with the tubing. At least one of the first and second reservoirs also transports fluid pressure to the pressure transfer element for conveyance to the diaphragm.

Abstract: A process is provided for ultrasonically welding a rigid thermoplastic, such as acrylic, and a flexible thermoplastic, such a polyvinyl chloride (PVC) doped with plasticizers. The rigid piece includes an energy director where the joint is to be located. The energy director includes first and second ridges running the length of the joint and a groove running between the first and second ridges. The energy director is placed against one side of the flexible piece, and an ultrasonic horn against the other side opposite the energy director. The two pieces are then welded together using standard ultrasonic technology. The shape of the energy director promotes the melting and flow of both pieces as they are being welded together.

Abstract: Peritoneal dialysis systems apply fluid pressure to move liquid. The systems can emulate either a fixed head height condition or different head height conditions, independent of the actual head height differential between the patient's peritoneal cavity and the external liquid source or destination. The systems can also switch between low-relative pressure flow mode when considerations of patient comfort and safety predominate and a high-relative pressure flow mode when considerations of processing speed predominate.