Patents by Inventor Douglas F. Burdi

Douglas F. Burdi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl-isochroman compounds and uses thereof
    Patent number: 11491133
    Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: November 8, 2022
    Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Carrie A. Bowen, Douglas F. Burdi, Michele L. R. Heffernan, Lee W. Herman, Linghong Xie
  • COMPOUNDS AND USES THEREOF
    Publication number: 20210093606
    Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
    Type: Application
    Filed: August 12, 2020
    Publication date: April 1, 2021
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Carrie A. Bowen, Douglas F. Burdi, Michele L. R. Heffernan, Lee W. Herman, Linghong Xie
  • Compounds and uses thereof
    Patent number: 10780074
    Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: September 22, 2020
    Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Carrie A. Bowen, Douglas F. Burdi, Michele L. R. Heffernan, Lee W. Herman, Linghong Xie
  • COMPOUNDS AND USES THEREOF
    Publication number: 20190038594
    Abstract: Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
    Type: Application
    Filed: August 1, 2018
    Publication date: February 7, 2019
    Inventors: Carrie A. Bowen, Douglas F. Burdi, Michele L.R. Heffernan, Lee W. Herman, Linghong Xie
  • TRICYCLIC DERIVATIVE
    Publication number: 20170273985
    Abstract: Disclosed are compounds useful as inhibitors of phosphodiesterase 1 (PDE1), compositions thereof, and methods of using the same.
    Type: Application
    Filed: September 17, 2015
    Publication date: September 28, 2017
    Inventors: Douglas F. Burdi, Daisuke Tanaka, Yuki Fujii, Muneo Kawasumi
  • TRICYCLIC GUANIDINE DERIVATIVE
    Publication number: 20160083400
    Abstract: Disclosed are compounds useful as inhibitors of Phosphodiesterase 1 (PDE1), compositions thereof, and methods of using the same.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 24, 2016
    Inventors: Douglas F. Burdi, Daisuke Tanaka, Hiroaki Fujiwara
  • TRICYCLIC PIPERAZINE DERIVATIVE
    Publication number: 20160083391
    Abstract: Disclosed are compounds useful as inhibitors of Phosphodiesterase 1 (PDE1), compositions thereof, and methods of using the same.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 24, 2016
    Inventors: Douglas F. Burdi, Daisuke Tanaka
  • Aryl sulfonamides useful as inhibitors of chemokine receptor activity
    Patent number: 8063222
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, X, Z, R2, X1, Ar, n, R3 and R4 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: November 22, 2011
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Mingshi Dai, Bing Guan, Robert A. Bennett, Douglas F. Burdi, Shomir Ghosh, Gang Li, Charles A. Minor, Tracy J. Jenkins
  • Aryl sulfonamides useful as inhibitors of chemokine receptor activity
    Publication number: 20090275556
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, X, Z, R2, X1, Ar, n, R3 and R4 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.
    Type: Application
    Filed: August 27, 2008
    Publication date: November 5, 2009
    Inventors: Mingshi Dai, Bing Guan, Roert A. Bennett, Douglas F. Burdi, Shomir Ghosh, Gang Li, Charles Minor, Tracy J. Jenkins
  • Aryl sulfonamides useful as inhibitors of chemokine receptor activity
    Patent number: 7491827
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, X, Z, R2, X1, Ar, n, R3 and R4 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: February 17, 2009
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Mingshi Dai, Bing Guan, Robert A. Bennett, Douglas F. Burdi, Shomir Ghosh, Gang Li, Charles Minor, Tracy J. Jenkins
  • CCR8 inhibitors
    Patent number: 7378525
    Abstract: Disclosed are CCR8 inhibitors represented by Structural Formulas (I): The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially asthma, by administering one of the disclosed CCR8 inhibitors to the subject.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: May 27, 2008
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Bing Guan, Charles Minor, Mingshi Dai, Shomir Ghosh, Tracy J. Jenkins, Gang Li, Douglas F. Burdi, Robert A. Bennett
  • CCR8 Inhibitors
    Publication number: 20040209948
    Abstract: Disclosed are CCR8 inhibitors represented by Structural Formulas (I): 1
    Type: Application
    Filed: December 23, 2003
    Publication date: October 21, 2004
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Bing Guan, Charles Minor, Mingshi Dai, Shomir Ghosh, Tracy J. Jenkins, Gang Li, Douglas F. Burdi, Robert A. Bennett