Patents by Inventor Douglas Howell
Douglas Howell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170066580Abstract: A packaging assembly can include a plurality of containers and a film. The packaging assembly can further include one or more tear lines disposed between adjacent containers, or between adjacent rows of containers. The tear lines can include scored tear lines or perforated tear lines. The scores or perforations can be formed by a laser, blade, or other implement. One or more containers can be removed from the packaging assembly by tearing the film along the tear line.Type: ApplicationFiled: February 20, 2015Publication date: March 9, 2017Inventors: Scott Douglas HOWELLS, Thomas R. LEE
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Patent number: 8501918Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors such as soluble TNF receptor from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) such as TNF? muteins capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as a TNF? mutein, capable of specifically binding to a targeted immune system inhibitor such as soluble TNF receptor.Type: GrantFiled: February 11, 2009Date of Patent: August 6, 2013Assignee: Cytologic, Inc.Inventor: Mark Douglas Howell
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Publication number: 20110201986Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as an antibody, capable of specifically binding to the targeted immune system inhibitor.Type: ApplicationFiled: October 29, 2010Publication date: August 18, 2011Applicant: CYTOLOGIC, INC.Inventors: Mark Douglas Howell, Cheryl Lynn Selinsky, Leland Charles Leber
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Patent number: 7993329Abstract: An ERCP catheter having a removable handle for a lithotriptor compatible basket is disclosed. The removable handle allows the catheter and handle assembly to be removed, leaving the basket in place within the duct and facilitates the use of a lithotriptor for mechanically crushing stone captured in the basket.Type: GrantFiled: August 13, 2003Date of Patent: August 9, 2011Assignee: Cook Medical Technologies LLCInventors: Douglas A. Howell, Matthew P. Carter, Jason D. Foushee, David M. Hardin
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Publication number: 20110184345Abstract: An ERCP catheter having a removable handle for a lithotriptor compatible basket is disclosed. The removable handle allows the catheter and handle assembly to be removed, leaving the basket in place within the duct and facilitates the use of a lithotriptor for mechanically crushing stone captured in the basket.Type: ApplicationFiled: January 27, 2011Publication date: July 28, 2011Applicant: Wilson-Cook Medical Inc.Inventors: Douglas A. Howell, Matthew P. Carter, Jason D. Foushee, David M. Hardin
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Publication number: 20100247822Abstract: A multilayer film includes at least an abuse layer that is laser scored, and a sealant layer that has discrete weakened portions, due to the laser scoring. The multilayer film may have a tensile strength of between about 0.40 and 2.5 pounds per 10 millimeters at the location of the one or more weakened portions. In certain aspects, the tensile strength of the multilayer film is between about 7 and 14 pounds per inch at the location of the laser scoring on the abuse layer. Also, a package is provided that is formed from one or more multilayer films having a scored abuse layer and a sealant layer with weakened portions that allow steam and/or pressure to be vented from the package during heating. Optionally, the abuse layer includes a shallow scoring portion to provide an easy-open feature. For instance, the package may be used to cook frozen foods contained in the package, such as in a microwave oven.Type: ApplicationFiled: February 2, 2010Publication date: September 30, 2010Inventors: Evan Michael Ziolkowski, Scott Douglas Howells, Gregory William Kokke, Brian Douglas
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Publication number: 20090227750Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors such as soluble TNF receptor from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) such as TNF? muteins capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as a TNF? mutein, capable of specifically binding to a targeted immune system inhibitor such as soluble TNF receptor.Type: ApplicationFiled: February 11, 2009Publication date: September 10, 2009Inventor: Mark Douglas Howell
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Publication number: 20080275376Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as an antibody, capable of specifically binding to the targeted immune system inhibitor.Type: ApplicationFiled: July 16, 2008Publication date: November 6, 2008Inventors: Mark Douglas Howell, Cheryl Lynn Selinsky, Leland Charles Leber
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Patent number: 7370904Abstract: A cover assembly for a vehicle carried open top container wherein a cover is connected at one end to a vertically adjustable tower and an opposite end to a cross member connected to a pair of pivot arms that are mounted at their lower ends to be pivoted by at least one hydraulic actuator that is mounted to the vehicle intermediate opposite ends of the container and adjacent the bottom thereof. An effective length of each pivot arm may be adjusted and locked in adjusted position.Type: GrantFiled: March 21, 2006Date of Patent: May 13, 2008Assignee: McNeilus Truck and Manufacturing, Inc.Inventors: Robert A. Wood, Jr., Douglas Howell
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Publication number: 20080075690Abstract: Provided is a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors such as soluble TNF receptor from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partners such as TNF? muteins capable of binding to and, thus, depleting the targeted immune system inhibitors from the biological fluids. Particularly useful is an adsorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as a TNF? mutein, capable of specifically binding to a targeted immune system inhibitor such as soluble TNF receptor.Type: ApplicationFiled: September 22, 2006Publication date: March 27, 2008Inventor: Mark Douglas Howell
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Publication number: 20070222253Abstract: A cover assembly for a vehicle carried open top container wherein a cover is connected at one end to a vertically adjustable tower and an opposite end to a cross member connected to a pair of pivot arms that are mounted at their lower ends to be pivoted by at least one hydraulic actuator that is mounted to the vehicle intermediate opposite ends of the container and adjacent the bottom thereof. An effective length of each pivot arm may be adjusted and locked in adjusted position.Type: ApplicationFiled: March 21, 2006Publication date: September 27, 2007Inventors: Robert Wood, Douglas Howell
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Publication number: 20050273150Abstract: A stent delivery system for positioning a first and second stent the first and second branch lumens of a bifurcation. The stent delivery system includes stent introducers and a sheath or catheter having a frangible wall. A method of delivering stents to anatomies such as bifurcated ducts or vessels.Type: ApplicationFiled: March 31, 2005Publication date: December 8, 2005Inventors: Douglas Howell, William Gibbons, Matthew Carter, Victor Clark
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Publication number: 20050084831Abstract: A training system uses a mechanical mock-up with electrically conductive probe points connected to electronically readable memories, and a simulated diagnostic tool to interface with a system or machine simulation for the purpose of operation, maintenance or procedure training. When a probe of a simulated diagnostic tool comes into contact with a probe point of the mechanical mock-up, the electronically readable memory supplies a unique identifier code that is communicated by the simulated diagnostic tool to the simulation to indicate the contact of the probe with the corresponding probe point. Complex wiring connections between the mechanical mock-up and a computer that runs the simulation are eliminated and construction of the training system is significantly simplified.Type: ApplicationFiled: October 17, 2003Publication date: April 21, 2005Inventors: Robert Ison, Christopher Conlon, Douglas Howell, David Allen, Mark Reeve-Fowkes, Laurence Norman, Stephen Taylor
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Publication number: 20040111082Abstract: An ERCP catheter having a removable handle for a lithotriptor compatible basket is disclosed. The removable handle allows the catheter and handle assembly to be removed, leaving the basket in place within the duct and facilitates the use of a lithotriptor for mechanically crushing stone captured in the basket.Type: ApplicationFiled: August 13, 2003Publication date: June 10, 2004Inventors: Douglas A. Howell, Matthew P. Carter, Jason D. Foushee, David M. Hardin
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Patent number: 6533782Abstract: A medical apparatus assembly (10) comprises a medical device (11) that includes a side port assembly 13 adapted to combine a first pathway (37) for infusion of fluids with a second pathway (38) for wire guide (12) into a first passageway (26) while the second passageway (27) includes the third pathway (39), which comprises a control member (24), such as an electrical wire. The side port assembly is configured such that the first passageway communicates with both a first port (16), such as a fitting for connecting to a syringe, and a second port (15) which includes a sealing mechanism (32), such as a Tuohy-Borst fitting, thereby allowing the wire guide to be preloaded, instead of requiring it to be removed prior to infusing fluids. Optionally, a third port (43) may be included when external communication with the second passageway, is desired, such as balloons or baskets.Type: GrantFiled: May 9, 2001Date of Patent: March 18, 2003Assignee: Wilson-Cook Medical IncorporatedInventors: Douglas A. Howell, Matthew P. Carter, William S. Gibbons, Jr., Jason D. Foushee
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Publication number: 20020119147Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as an antibody, capable of specifically binding to the targeted immune system inhibitor.Type: ApplicationFiled: February 7, 2002Publication date: August 29, 2002Applicant: CytoLogic, LLCInventors: Mark Douglas Howell, Cheryl Lynn Selinsky, Leland Charles Leber
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Patent number: 6379708Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as an antibody, capable of specifically binding to the targeted immune system inhibitor.Type: GrantFiled: November 20, 1999Date of Patent: April 30, 2002Assignees: Cytologic, LLC, Colorado State University Research FoundationInventors: Mark Douglas Howell, Cheryl Lynn Selinsky, Leland Charles Leber
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Publication number: 20020049423Abstract: Disclosed is a medical apparatus assembly (10) comprising a medical device (11) that includes a side port assembly 13 adapted to combine a first pathway (37) for infusion of fluids with a second pathway (38) for wire guide (12) into a first passageway (26) while the second passageway (27) includes the third pathway (39), which comprises a control member (24), such as an electrical wire. The side port assembly is configured such that the first passageway communicates with both a first port (16), such as a fitting for connecting to a syringe, and a second port (15) which includes a sealing mechanism (32), such as a Tuohy-Borst fitting, thereby allowing the wire guide to be preloaded, instead of requiring it to be removed prior to infusing fluids. Optionally, a third port (43) may be included when external communication with the second passageway, is desired, such as balloons or baskets.Type: ApplicationFiled: May 9, 2001Publication date: April 25, 2002Applicant: Wilson-Cook Medical Inc.Inventors: Douglas A. Howell, Matthew P. Carter, William S. Gibbons, Jason D. Foushee