Patents by Inventor Douglas I. Hepler

Douglas I. Hepler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PIMOBENDAN FORMULATION AND METHOD OF USE THEREOF
    Publication number: 20240382478
    Abstract: Provided herein are chewable oral formulations including pimobendan for use in mammals to treat cardiac disorders.
    Type: Application
    Filed: July 26, 2024
    Publication date: November 21, 2024
    Inventors: Douglas I. Hepler, Michael S. Daniel, Neil E. Paulsen, Gail L. Dempsey
  • OTIC FORMULATIONS, METHODS AND DEVICES
    Publication number: 20240285651
    Abstract: The present invention relates to a formulation and method for treating an ear infection, especially otomycosis and otitis externa, by administering a one-time only treatment comprising an antibiotic, antifungal, and an anti-inflammatory in a thick, otic carrier. In one embodiment, the formulation comprises a therapeutically effective amount of active ingredients including a marbofloxacin, terbinafine and/or clotrimazole and dexamethasone.
    Type: Application
    Filed: April 17, 2024
    Publication date: August 29, 2024
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea A. Erxleben, Neil E. Paulsen
  • INJECTABLE ANTIBIOTIC FORMULATIONS AND USE THEREOF
    Publication number: 20240285662
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions containing azithromycin with low toxicity, especially for administration to felines, are provided herein.
    Type: Application
    Filed: May 1, 2024
    Publication date: August 29, 2024
    Inventors: Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson, Douglas I. Hepler, Raymond Petzold
  • LONG-ACTING INJECTABLE FORMULATIONS AND USE THEREOF
    Publication number: 20240245713
    Abstract: Provided herein are long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection.
    Type: Application
    Filed: April 3, 2024
    Publication date: July 25, 2024
    Inventors: Gail L. Dempsey, Douglas I. Hepler, Dorothea Erxleben, Michael S. Daniel, Neil E. Paulsen
  • Injectable antibiotic formulations and use thereof
    Patent number: 12005071
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions containing azithromycin with low toxicity, especially for administration to felines, are provided herein.
    Type: Grant
    Filed: March 20, 2023
    Date of Patent: June 11, 2024
    Assignee: Dechra Veterinary Products, LLC
    Inventors: Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson, Douglas I. Hepler, Raymond Petzold
  • Otic formulations, methods and devices
    Patent number: 11986483
    Abstract: The present invention relates to a formulation and method for treating an ear infection, especially otomycosis and otitis externa, by administering a one-time only treatment comprising an antibiotic, antifungal, and an anti-inflammatory in a thick, otic carrier. In one embodiment, the formulation comprises a therapeutically effective amount of active ingredients including a marbofloxacin, terbinafine and/or clotrimazole and dexamethasone.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: May 21, 2024
    Assignee: Dechra Veterinary Products, LLC
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea A. Erxleben, Neil E. Paulsen
  • THERAPEUTIC FORMULATIONS AND USES THEREOF
    Publication number: 20230285354
    Abstract: Provided herein are pharmaceutically acceptable compositions containing a selective cyclooxygenase-2 (COX-2) inhibitor (coxib) and optionally buprenorphine. In particular, compositions containing a coxib formulated for oral, topical or subcutaneous administration to treat pain or inflammation are described.
    Type: Application
    Filed: May 12, 2023
    Publication date: September 14, 2023
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Roland Johnson, Michael Kelly, Michael Daniel, Neil Paulsen, Bert Clayton
  • INJECTABLE ANTIBIOTIC FORMULATIONS AND USE THEREOF
    Publication number: 20230226091
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions containing azithromycin with low toxicity, especially for administration to felines, are provided herein.
    Type: Application
    Filed: March 20, 2023
    Publication date: July 20, 2023
    Inventors: Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson, Douglas I. Hepler, Raymond Petzold
  • Injectable antibiotic formulations and use thereof
    Patent number: 11628180
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions containing azithromycin with low toxicity, especially for administration to felines, are provided herein.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: April 18, 2023
    Assignee: Dechra Veterinary Products, LLC
    Inventors: Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson, Douglas I. Hepler, Raymond Petzold
  • INJECTABLE ANTIBIOTIC FORMULATIONS AND USE THEREOF
    Publication number: 20220031724
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions containing azithromycin with low toxicity, especially for administration to felines, are provided herein.
    Type: Application
    Filed: March 10, 2021
    Publication date: February 3, 2022
    Inventors: Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson, Douglas I. Hepler, Raymond Petzold
  • Long-acting non-aqueous injectable formulations and use thereof
    Patent number: 11058629
    Abstract: Provided herein are long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection, in particular analgesics such as buprenorphine.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: July 13, 2021
    Assignee: Piedmont Animal Health Inc.
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea Erxleben
  • THERAPEUTIC FORMULATIONS AND USES THEREOF
    Publication number: 20210186923
    Abstract: Provided herein are pharmaceutically acceptable compositions containing a selective cyclooxygenase-2 (COX-2) inhibitor (coxib) and optionally buprenorphine. In particular, compositions containing a coxib formulated for oral, topical or subcutaneous administration to treat pain or inflammation are described.
    Type: Application
    Filed: October 29, 2020
    Publication date: June 24, 2021
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Roland Johnson, Michael Kelly, Michael S. Daniel, Neil E. Paulsen, Bert Clayton
  • PIMOBENDAN FORMULATION AND METHOD OF USE THEREOF
    Publication number: 20210177842
    Abstract: Provided herein are chewable oral formulations including pimobendan for use in mammals to treat cardiac disorders.
    Type: Application
    Filed: October 23, 2020
    Publication date: June 17, 2021
    Inventors: Douglas I. Hepler, Michael S. Daniel, Neil E. Paulsen, Gail L. Dempsey
  • OTIC FORMULATIONS, METHODS AND DEVICES
    Publication number: 20210106597
    Abstract: The present invention relates to a formulation and method for treating an ear infection, especially otomycosis and otitis externa, by administering a one-time only treatment comprising an antibiotic, antifungal, and an anti-inflammatory in a thick, otic carrier. In one embodiment, the formulation comprises a therapeutically effective amount of active ingredients including a marbofloxacin, terbinafine and/or clotrimazole and dexamethasone.
    Type: Application
    Filed: October 8, 2020
    Publication date: April 15, 2021
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea A. Erxleben, Neil E. Paulsen
  • INJECTABLE ANTIBIOTIC FORMULATIONS AND USE THEREOF
    Publication number: 20210106602
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin and tulathromycin. In particular, compositions containing azithromycin or tulathromycin with low toxicity, especially for administration to canines, are provided herein.
    Type: Application
    Filed: May 22, 2020
    Publication date: April 15, 2021
    Inventors: Douglas I. Hepler, Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson
  • LONG-ACTING NON-AQUEOUS INJECTABLE FORMULATIONS AND USE THEREOF
    Publication number: 20200237653
    Abstract: Provided herein are long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection, in particular analgesics such as buprenorphine.
    Type: Application
    Filed: January 31, 2020
    Publication date: July 30, 2020
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea Erxleben
  • Long-acting non-aqueous injectable formulations and use thereof
    Patent number: 10555899
    Abstract: Provided herein are long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection, in particular analgesics such as buprenorphine.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: February 11, 2020
    Assignee: Piedmont Animal Health, LLC
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea Erxleben
  • THERAPEUTIC FORMULATIONS AND USES THEREOF
    Publication number: 20190142789
    Abstract: Provided herein are pharmaceutically acceptable compositions containing a selective cyclooxygenase-2 (COX-2) inhibitor (coxib) and optionally buprenorphine. In particular, compositions containing a coxib formulated for oral, topical or subcutaneous administration to treat pain or inflammation are described.
    Type: Application
    Filed: August 9, 2018
    Publication date: May 16, 2019
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Roland Johnson, Michael Kelly, Michael Daniel, Neil Paulsen, Bert Clayton
  • LONG-ACTING NON-AQUEOUS INJECTABLE FORMULATIONS AND USE THEREOF
    Publication number: 20180344629
    Abstract: Provided herein are long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection, in particular analgesics such as buprenorphine.
    Type: Application
    Filed: June 5, 2018
    Publication date: December 6, 2018
    Inventors: Douglas I. Hepler, Gail L. Dempsey, Dorothea Erxleben
  • INJECTABLE ANTIBIOTIC FORMULATIONS AND USE THEREOF
    Publication number: 20180256622
    Abstract: Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin and tulathromycin. In particular, compositions containing azithromycin or tulathromycin with low toxicity, especially for administration to canines, are provided herein.
    Type: Application
    Filed: March 8, 2018
    Publication date: September 13, 2018
    Inventors: Douglas I. Hepler, Neil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson