Patents by Inventor Douglas J. M. Allan

Douglas J. M. Allan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for making steroidal peracyl glycosides
    Patent number: 5530107
    Abstract: Processes for the synthesis of tigogenin beta-O-cellobioside heptaalkanoate which is an intermediate for the known hypocholesterolemic agent tigogenin beta-cellobioside. The process comprises reacting .alpha.-cellobiosyl bromide heptaalkanoate and .beta.-tigogenin in the presence of zinc fluoride or zinc cyanide under conditions capable of forming said tigogenyl .beta.-O-cellobioside heptaalkanoate. The analogous preparations of hecogenin .beta.-O-cellobioside heptaalkanoate, 11-ketotigogenin .beta.-O-cellobioside heptaalkanoate, and diosgenin .beta.-O-cellobioside heptaalkanoate are also disclosed. The process provides both high .beta.-anomeric selectivity and high yields.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: June 25, 1996
    Assignee: Pfizer Inc.
    Inventors: Douglas J. M. Allan, Frank R. Busch, John F. Lambert, Russell J. Shine, Stanley W. Walinsky