Abstract: A method of targeted advertising includes generating a targeted advertising and/or promotional campaign material corresponding to a client's selections, fulfilling the targeted advertising and/or promotional campaign material, and providing a response tracking analysis to the client. The targeted advertising and/or promotional campaign material includes a response tracking capability. Access for the client to contact a central facility having public and/or private client databases with list management capabilities can be provided on-line via a client web site. The client can choose from a selection of templates to design of the targeted advertising and/or promotional campaign material. Also, the client can choose from a selection of intended recipients by using and/or modifying a new or pre-existing customer list. The targeted advertising and/or promotional campaign material can be manufactured and distributed to the intended recipients.