Abstract: A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, or rodents, that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus within a magnetic field produced by the magnetic resonance imaging apparatus such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.

Abstract: Embodiments relate to an imaging system that includes a collimator assembly having two or more pinhole apertures therein. In one embodiment, the imaging system is configured so that two or more of the pinhole apertures have different focal lengths. The imaging system further includes a detector assembly configured to generate one or more signals in response to gamma photons that pass through the two or more pinhole apertures. Additional embodiments also relate to methods of changing collimator performance and methods of imaging a volume.

Abstract: A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, or rodents, that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus within a magnetic field produced by the magnetic resonance imaging apparatus such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.

Abstract: A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, rodents (especially mice and rats), that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus in close proximity such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.

Abstract: An multi-modality imaging system for imaging of an object under study that includes a magnetic resonance imaging (MRI) apparatus and an MRI-compatible single-photon nuclear imaging apparatus imbedded within the RF coil of the MRI system such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study during the imaging session.

Abstract: Methods and systems for improving image quality of single photon nuclear imaging systems, such as single photon emission computed tomography (SPECT) systems for imaging of an object under study, such as small objects including small animals of different sizes using synthetic apertures. The methods and systems include processes and instrumentations for high-resolution, high detection efficiency leading to lower image noise and artifact-free synthetic aperture single photon nuclear images, such as SPECT images. Also, the method and systems provide design parameters, hardware settings, and data acquisition processes for optimal imaging of objects having different sizes.

Abstract: A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, rodents (especially mice and rats), that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus in close proximity such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.

Abstract: A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, rodents (especially mice and rats), that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus in close proximity such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.

Abstract: Methods and systems for improving image quality of single photon nuclear imaging systems, such as single photon emission computed tomography (SPECT) systems for imaging of an object under study, such as small objects including small animals of different sizes using synthetic apertures. The methods and systems include processes and instrumentations for high-resolution, high detection efficiency leading to lower image noise and artifact-free synthetic aperture single photon nuclear images, such as SPECT images. Also, the method and systems provide design parameters, hardware settings, and data acquisition processes for optimal imaging of objects having different sizes.

Abstract: An adaptive opto-emission imaging device includes a detector having a detector face and a back surface. The detector detects radiation emanating from an object positioned in the direction of the detector face, and produces a radiopharmaceutical distribution profile of the detected radiation. An image capturing device such as a video camera provided at the detector face of the detector produces a live visual image of the object. A display device provided at the back surface of the detector displays the radiopharmaceutical distribution profile and/or the live visual image of the object. The adaptive opto-emission imaging device greatly reduces the amount of computation and time to provide real time image guidance, for example to physicians using the device to perform an image-guided surgical procedure.

Abstract: A radionuclide scanner in which multiple detectors are equipped with collimators such that a circular rotation of the detector around a target provides the movement needed for collimator sampling. This collimator sampling is accomplished through strategic placement of the detector heads relative to each other such that for any given projection, a complete imaging of the projection is acquired by summing the complementary contributions of the multiple detector heads at the projection under consideration.

Abstract: An adaptive opto-emission imaging device includes a detector having a detector face and a back surface. The detector detects radiation emanating from an object positioned in the direction of the detector face, and produces a radiopharmaceutical distribution profile of the detected radiation. An image capturing device such as a video camera provided at the detector face of the detector produces a live visual image of the object. A display device provided at the back surface of the detector displays the radiopharmaceutical distribution profile and/or the live visual image of the object. The adaptive opto-emission imaging device greatly reduces the amount of computation and time to provide real time image guidance, for example to physicians using the device to perform an image-guided surgical procedure.

Abstract: A radionuclide scanner in which multiple detectors are equipped with collimators such that a circular rotation of the detector around a target provides the movement needed for collimator sampling. This collimator sampling is accomplished through strategic placement of the detector heads relative to each other such that for any given projection, a complete imaging of the projection is acquired by summing the complementary contributions of the multiple detector heads at the projection under consideration.